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Photoacoustic imaging (PAI) is an emerging non-invasive imaging modality combining the advantages of deep ultrasound penetration and high optical contrast. Image reconstruction is an essential topic in PAI, which is unfortunately an…

图像与视频处理 · 电气工程与系统科学 2019-08-06 Hengrong Lan , Daohuai Jiang , Changchun Yang , Fei Gao

Recent advances in photoacoustic (PA) imaging have enabled detailed images of microvascular structure and quantitative measurement of blood oxygenation or perfusion. Standard reconstruction methods for PA imaging are based on solving an…

信号处理 · 电气工程与系统科学 2020-04-17 MinWoo Kim , Geng-Shi Jeng , Ivan Pelivanov , Matthew O'Donnell

Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…

图像与视频处理 · 电气工程与系统科学 2022-04-13 Hengrong Lan , Jiali Gong , Fei Gao

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

Photoacoustic imaging (PAI) is a promising emerging imaging modality that enables spatially resolved imaging of optical tissue properties up to several centimeters deep in tissue, creating the potential for numerous exciting clinical…

医学物理 · 物理学 2021-04-15 Janek Gröhl , Melanie Schellenberg , Kris Dreher , Lena Maier-Hein

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

计算机视觉与模式识别 · 计算机科学 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Multispectral photoacoustic imaging (PAI) is an emerging imaging modality which enables the recovery of functional tissue parameters such as blood oxygenation. However, the underlying inverse problems are potentially ill-posed, meaning that…

Photoacoustic imaging (PAI) can image high-resolution structures of clinical interest such as vascularity in cancerous tumor monitoring. When imaging human subjects, geometric restrictions force limited-view data retrieval causing imaging…

图像与视频处理 · 电气工程与系统科学 2022-04-27 Rafael Orozco , Mathias Louboutin , Felix J. Herrmann

Photoacoustic imaging (PAI) is a powerful imaging modality that relies on the PA effect. PAI works on the principle of electromagnetic energy absorption by the exogenous contrast agents and/or endogenous molecules present in the biological…

光学 · 物理学 2020-12-16 Mohsin Zafar , Qiuyun Xu , Rayyan Manwar

Applying standard algorithms to sparse data problems in photoacoustic tomography (PAT) yields low-quality images containing severe under-sampling artifacts. To some extent, these artifacts can be reduced by iterative image reconstruction…

数值分析 · 数学 2024-12-20 Stephan Antholzer , Johannes Schwab , Robert Nuster , Markus Haltmeier

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct…

图像与视频处理 · 电气工程与系统科学 2020-06-02 Anthony DiSpirito , Daiwei Li , Tri Vu , Maomao Chen , Dong Zhang , Jianwen Luo , Roarke Horstmeyer , Junjie Yao

Photoacoustic imaging combines the high contrast of optical imaging with the deep penetration depth of ultrasonic imaging, showing great potential in cerebrovascular disease detection. However, the ultrasonic wave suffers strong attenuation…

医学物理 · 物理学 2025-09-08 Pengcheng Wan , Fan Zhang , Yuting Shen , Hulin Zhao , Xiran Cai , Xiaohua Feng , Fei Gao

Photoacoustic microscopy (PAM) has been a promising biomedical imaging technology in recent years. However, the point-by-point scanning mechanism results in low-speed imaging, which limits the application of PAM. Reducing sampling density…

图像与视频处理 · 电气工程与系统科学 2020-06-09 Jiasheng Zhou , Da He , Xiaoyu Shang , Zhendong Guo , Sung-liang Chen , Jiajia Luo

Photoacoustic imaging (PAI) represents an innovative biomedical imaging modality that harnesses the advantages of optical resolution and acoustic penetration depth while ensuring enhanced safety. Despite its promising potential across a…

计算机视觉与模式识别 · 计算机科学 2026-02-03 Lei Wang , Weiming Zeng , Kai Long , Hongyu Chen , Rongfeng Lan , Li Liu , Wai Ting Siok , Nizhuan Wang

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

Photoacoustic (PA) imaging is a biomedical imaging modality capable of acquiring high-contrast images of optical absorption at depths much greater than traditional optical imaging techniques. However, practical instrumentation and geometry…

计算机视觉与模式识别 · 计算机科学 2021-06-02 Mengjie Guo , Hengrong Lan , Changchun Yang , Fei Gao

Recent advances in deep learning for tomographic reconstructions have shown great potential to create accurate and high quality images with a considerable speed-up. In this work we present a deep neural network that is specifically designed…

计算机视觉与模式识别 · 计算机科学 2020-09-07 Andreas Hauptmann , Felix Lucka , Marta Betcke , Nam Huynh , Jonas Adler , Ben Cox , Paul Beard , Sebastien Ourselin , Simon Arridge

Deep learning has been used to improve photoacoustic (PA) image reconstruction. One major challenge is that errors cannot be quantified to validate predictions when ground truth is unknown. Validation is key to quantitative applications,…

图像与视频处理 · 电气工程与系统科学 2024-07-04 Ruibo Shang , Geoffrey P. Luke , Matthew O'Donnell

Accurate measurement of optical absorption coefficients from photoacoustic imaging (PAI) data would enable direct mapping of molecular concentrations, providing vital clinical insight. The ill-posed nature of the problem of absorption…

图像与视频处理 · 电气工程与系统科学 2023-06-13 Janek Gröhl , Thomas R. Else , Lina Hacker , Ellie V. Bunce , Paul W. Sweeney , Sarah E. Bohndiek

Significance: Photoacoustic imaging (PAI) promises to measure spatially-resolved blood oxygen saturation, but suffers from a lack of accurate and robust spectral unmixing methods to deliver on this promise. Accurate blood oxygenation…

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