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Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor…

亚细胞过程 · 定量生物学 2017-12-19 Bjorn Becker , M. Reza Shaebani , Domenik Rammo , Tobias Bubel , Ludger Santen , Manfred J. Schmitt

Salient Object Detection (SOD) with deep learning often requires substantial computational resources and large annotated datasets, making it impractical for resource-constrained applications. Lightweight models address computational demands…

计算机视觉与模式识别 · 计算机科学 2025-04-16 Leonardo M. Joao , Jancarlo F. Gomes , Silvio J. F. Guimaraes , Ewa Kijak , Alexandre X. Falcao

We systematically evaluate a Deep Learning (DL) method in a 3D medical image segmentation task. Our segmentation method is integrated into the radiosurgery treatment process and directly impacts the clinical workflow. With our method, we…

Recently, wearable emotion recognition based on peripheral physiological signals has drawn massive attention due to its less invasive nature and its applicability in real-life scenarios. However, how to effectively fuse multimodal data…

人机交互 · 计算机科学 2023-04-03 Yujin Wu , Mohamed Daoudi , Ali Amad

Receptor-ligand binding is a critical first step in signal transduction and the duration of the interaction can impact signal generation. In mammalian cells, clustering of receptors may be facilitated by heterogeneous zones of lipids, known…

亚细胞过程 · 定量生物学 2009-11-10 Manoj Gopalakrishnan , Kimberly Forsten-Williams , Matthew A. Nugent , Uwe C. Tauber

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

组织与器官 · 定量生物学 2019-02-14 Melinda Liu Perkins , Murat Arcak

Transformer-based methods have demonstrated superior performance for monocular 3D object detection recently, which aims at predicting 3D attributes from a single 2D image. Most existing transformer-based methods leverage both visual and…

计算机视觉与模式识别 · 计算机科学 2023-09-04 Xuan He , Fan Yang , Kailun Yang , Jiacheng Lin , Haolong Fu , Meng Wang , Jin Yuan , Zhiyong Li

Multiphoton absorption is of vital importance in many spectroscopic, microscopic or lithographic applications. However, given that it is an inherently weak process, the detection of multiphoton absorption signals typically requires large…

量子物理 · 物理学 2023-05-31 Shahram Panahiyan , Carlos Sánchez Muñoz , Maria V. Chekhova , Frank Schlawin

Joint object detection and semantic segmentation can be applied to many fields, such as self-driving cars and unmanned surface vessels. An initial and important progress towards this goal has been achieved by simply sharing the deep…

计算机视觉与模式识别 · 计算机科学 2018-09-26 Jiale Cao , Yanwei Pang , Xuelong Li

In drug discovery, structure-based virtual high-throughput screening (vHTS) campaigns aim to identify bioactive ligands or "hits" for therapeutic protein targets from docked poses at specific binding sites. However, while generally…

定量方法 · 定量生物学 2021-12-03 Pawel Gniewek , Bradley Worley , Kate Stafford , Henry van den Bedem , Brandon Anderson

Coupling an isolated emitter to a single mode of the electromagnetic field is now routinely achieved and well understood. Current efforts aim to explore the coherent dynamics of emitters coupled to several electromagnetic modes (EM).…

To enable robots to develop human-like fine manipulation, it is essential to understand how mechanical compliance, multi-modal sensing, and purposeful interaction jointly shape tactile perception. In this study, we use a dedicated modular…

机器人学 · 计算机科学 2025-08-14 Anirvan Dutta , Alexis WM Devillard , Zhihuan Zhang , Xiaoxiao Cheng , Etienne Burdet

In recent years, there have been attempts to increase the kernel size of Convolutional Neural Nets (CNNs) to mimic the global receptive field of Vision Transformers' (ViTs) self-attention blocks. That approach, however, quickly hit an upper…

计算机视觉与模式识别 · 计算机科学 2024-07-16 Shahaf E. Finder , Roy Amoyal , Eran Treister , Oren Freifeld

We introduce a model description of femtosecond laser induced desorption at surfaces. The substrate part of the system is taken into account as a (possibly semi-infinite) linear chain. Here, being especially interested in the early stages…

介观与纳米尺度物理 · 物理学 2016-05-25 Emil Boström , Anders Mikkelsen , Claudio Verdozzi

Recently, radical progress in machine learning (ML) has revolutionized computational materials science, enabling unprecedentedly rapid materials discovery and property prediction, but the quantum many-body problem -- which is the key to…

材料科学 · 物理学 2025-07-09 Bowen Hou , Xian Xu , Jinyuan Wu , Diana Y. Qiu

Deep convolutional neural networks (CNNs) have demonstrated impressive performance on many visual tasks. Recently, they became useful models for the visual system in neuroscience. However, it is still not clear what are learned by CNNs in…

神经元与认知 · 定量生物学 2020-02-19 Qi Yan , Yajing Zheng , Shanshan Jia , Yichen Zhang , Zhaofei Yu , Feng Chen , Yonghong Tian , Tiejun Huang , Jian K. Liu

Weak interactions form the core basis of a vast number of biological processes, in particular, those involving intrinsically disordered proteins. Here, we establish a new technique capable of probing these weak interactions between…

生物物理 · 物理学 2019-10-02 Indrani Chakraborty , Gil Rahamim , Ram Avinery , Yael Roichman , Roy Beck

The electronic and magnetic properties of many strongly-correlated systems are controlled by a limited number of states, located near the Fermi level and well isolated from the rest of the spectrum. This opens a formal way for combining the…

强关联电子 · 物理学 2010-07-15 I. V. Solovyev

We investigate the equilibrium properties of a colloidal solution in contact with a soft interface. As a result of symmetry breaking, surface effects are generally prevailing in confined colloidal systems. In this Letter, particular…

统计力学 · 物理学 2015-06-24 Hamid Kaidi , Thomas Bickel , Mabrouk Benhamou

Biological studies on in vitro cell cultures are of fundamental importance to investigate cells response to external stimuli, such as new drugs for treatment of specific pathologies, or to study communication between electrogenic cells.…

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