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Diffuse optical tomography (DOT) has been investigated as an alternative imaging modality for breast cancer detection thanks to its excellent contrast to hemoglobin oxidization level. However, due to the complicated non-linear photon…

In optical diffraction tomography (ODT), the three-dimensional scattering potential of a microscopic object rotating around its center is recovered by a series of illuminations with coherent light. Reconstruction algorithms such as the…

数值分析 · 数学 2022-09-02 Robert Beinert , Michael Quellmalz

Intensity diffraction tomography (IDT) refers to a class of optical microscopy techniques for imaging the 3D refractive index (RI) distribution of a sample from a set of 2D intensity-only measurements. The reconstruction of artifact-free RI…

图像与视频处理 · 电气工程与系统科学 2022-08-16 Renhao Liu , Yu Sun , Jiabei Zhu , Lei Tian , Ulugbek Kamilov

Holographic Tomography (HT) or Optical Diffraction Tomography (ODT) provides slice-by-slice information about the refractive index (RI) of three-dimensional (3D) samples and is emerging as an important label-free imaging modality for Life…

图像与视频处理 · 电气工程与系统科学 2025-04-22 N Goyal , K Khare

We present a novel illumination control technique for optical diffraction tomography (ODT). Various spatial frequencies of beam illumination were controlled by displaying time-averaged sinusoidal patterns using a digital micromirror device…

生物物理 · 物理学 2017-04-05 Kyeoreh Lee , Kyoohyun Kim , Geon Kim , Seungwoo Shin , YongKeun Park

Refractive Index Tomography is the inverse problem of reconstructing the continuously-varying 3D refractive index in a scene using 2D projected image measurements. Although a purely refractive field is not directly visible, it bends light…

计算机视觉与模式识别 · 计算机科学 2023-12-06 Brandon Zhao , Aviad Levis , Liam Connor , Pratul P. Srinivasan , Katherine L. Bouman

Label-free tomographic microscopy offers a compelling means to visualize three-dimensional (3D) refractive index (RI) distributions from two-dimensional (2D) intensity measurements. However, limited forward-model accuracy and the ill-posed…

光学 · 物理学 2025-02-27 Delong Yang , Shaohui Zhang , Jiasong Sun , Chao Zuo , Qun Hao

In tomographic reconstruction, the image quality of the reconstructed images can be significantly degraded by defects in the measured two-dimensional (2D) raw image data. Despite the importance of screening defective 2D images for robust…

图像与视频处理 · 电气工程与系统科学 2019-10-29 Donghun Ryu , Youngju Jo , Jihyeong Yoo , Taean Chang , Daewoong Ahn , Young Seo Kim , Geon Kim , Hyun-seok Min , Yongkeun Park

Optical diffraction tomography (ODT) is a three-dimensional (3D) label-free imaging technique. The 3D refractive index distribution of a sample can be reconstructed from multiple two-dimensional optical field images via ODT. Herein, we…

光学 · 物理学 2021-02-03 Chansuk Park , Kyeoreh Lee , Yoonseok Baek , Yongkeun Park

Recent object detectors have achieved impressive accuracy in identifying objects seen during training. However, real-world deployment often introduces novel and unexpected objects, referred to as out-of-distribution (OOD) objects, posing…

We propose and experimentally demonstrate temporally low-coherent optical diffraction tomography (ODT) based on angle-scanning Mach-Zehnder interferometry. Using a digital micromirror device based on diffractive tilting, we successfully…

光学 · 物理学 2018-07-17 KyeoReh Lee , Seungwoo Shin , Zahid Yaqoob , Peter T. C. So , YongKeun Park

Conebeam CT using a circular trajectory is quite often used for various applications due to its relative simple geometry. For conebeam geometry, Feldkamp, Davis and Kress algorithm is regarded as the standard reconstruction method, but this…

图像与视频处理 · 电气工程与系统科学 2020-06-04 Yoseob Han , Junyoung Kim , Jong Chul Ye

Advancements in synthesized speech have created a growing threat of impersonation, making it crucial to develop deepfake algorithm recognition. One significant aspect is out-of-distribution (OOD) detection, which has gained notable…

音频与语音处理 · 电气工程与系统科学 2024-06-05 Renmingyue Du , Jixun Yao , Qiuqiang Kong , Yin Cao

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

图像与视频处理 · 电气工程与系统科学 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic

Eye movements, blinking and other motion during the acquisition of optical coherence tomography (OCT) can lead to artifacts, when processed to OCT angiography (OCTA) images. Affected scans emerge as high intensity (white) or missing (black)…

图像与视频处理 · 电气工程与系统科学 2020-01-09 Julian Hossbach , Lennart Husvogt , Martin F. Kraus , James G. Fujimoto , Andreas K. Maier

Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However,…

光学 · 物理学 2025-02-07 Yan Liu , Jonathan Dong , Thanh-an Pham , François Marelli , Michael Unser

The non-interference three-dimensional refractive index(RI) tomography has attracted extensive attention in the life science field for its simple system implementation and robust imaging performance. However, the complexity inherent in the…

光学 · 物理学 2023-06-13 Delong Yang , Shaohui Zhang , Yao Hu , Qun Hao

Non-contact measurement of the refractive index and thickness of multilayer biological tissues is of great significance for biomedical applications and can greatly improve medical diagnosis and treatment. In this work, we introduce a…

光学 · 物理学 2024-04-19 Yu-Lin Ku , Yao-Gen Shu

Clustering is a fundamental task in the computer vision and machine learning community. Although various methods have been proposed, the performance of existing approaches drops dramatically when handling incomplete high-dimensional data…

计算机视觉与模式识别 · 计算机科学 2021-03-23 Mingjie Luo , Siwei Wang , Xinwang Liu , Wenxuan Tu , Yi Zhang , Xifeng Guo , Sihang Zhou , En Zhu

Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…

光学 · 物理学 2024-08-20 Renzhi He , Yucheng Li , Junjie Chen , Yi Xue