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In post-operative radiotherapy for prostate cancer, the cancerous prostate gland has been surgically removed, so the clinical target volume (CTV) to be irradiated encompasses the microscopic spread of tumor cells, which cannot be visualized…

Inter-observer variation is a significant problem in clinical target volume(CTV) segmentation in postoperative settings, where there is no gross tumor present. In this scenario, the CTV is not an anatomically established structure, but one…

When a pre-trained general auto-segmentation model is deployed at a new institution, a support framework in the proposed Prior-guided DDL network will learn the systematic difference between the model predictions and the final contours…

计算机视觉与模式识别 · 计算机科学 2022-11-22 Anjali Balagopal , Dan Nguyen , Ti Bai , Michael Dohopolski , Mu-Han Lin , Steve Jiang

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

计算机视觉与模式识别 · 计算机科学 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Prostate cancer (PCa) is the most prevalent cancer among men in the United States, accounting for nearly 300,000 cases, 29\% of all diagnoses and 35,000 total deaths in 2024. Traditional screening methods such as prostate-specific antigen…

图像与视频处理 · 电气工程与系统科学 2025-05-27 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Segmentation of Prostate Cancer (PCa) tissues from Gleason graded histopathology images is vital for accurate diagnosis. Although deep learning (DL) based segmentation methods achieve state-of-the-art accuracy, they rely on large datasets…

图像与视频处理 · 电气工程与系统科学 2021-10-04 Dwarikanath Mahapatra

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

图像与视频处理 · 电气工程与系统科学 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

Accurate medical image segmentation is of utmost importance for enabling automated clinical decision procedures. However, prevailing supervised deep learning approaches for medical image segmentation encounter significant challenges due to…

计算机视觉与模式识别 · 计算机科学 2023-09-04 Sanaz Karimijafarbigloo , Reza Azad , Amirhossein Kazerouni , Yury Velichko , Ulas Bagci , Dorit Merhof

Deep learning based semi-supervised learning (SSL) methods have achieved strong performance in medical image segmentation, which can alleviate doctors' expensive annotation by utilizing a large amount of unlabeled data. Unlike most existing…

图像与视频处理 · 电气工程与系统科学 2022-07-26 Zihang Xu , Zhenghua Xu , Shuo Zhang , Thomas Lukasiewicz

Current deep learning approaches for prostate cancer lesion segmentation achieve limited performance, with Dice scores of 0.32 or lower in large patient cohorts. To address this limitation, we investigate synthetic correlated diffusion…

计算机视觉与模式识别 · 计算机科学 2025-11-12 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Achieving accurate and automated tumor segmentation plays an important role in both clinical practice and radiomics research. Segmentation in medicine is now often performed manually by experts, which is a laborious, expensive and…

图像与视频处理 · 电气工程与系统科学 2022-11-07 Zhengyong Huang , Sijuan Zou , Guoshuai Wang , Zixiang Chen , Hao Shen , Haiyan Wang , Na Zhang , Lu Zhang , Fan Yang , Haining Wangg , Dong Liang , Tianye Niu , Xiaohua Zhuc , Zhanli Hua

Background and purpose: Radiation-induced erectile dysfunction (RiED) is commonly seen in prostate cancer patients. Clinical trials have been developed in multiple institutions to investigate whether dose-sparing to the…

图像与视频处理 · 电气工程与系统科学 2023-02-06 Anjali Balagopal , Michael Dohopolski , Young Suk Kwon , Steven Montalvo , Howard Morgan , Ti Bai , Dan Nguyen , Xiao Liang , Xinran Zhong , Mu-Han Lin , Neil Desai , Steve Jiang

In medical images, various types of lesions often manifest significant differences in their shape and texture. Accurate medical image segmentation demands deep learning models with robust capabilities in multi-scale and boundary feature…

图像与视频处理 · 电气工程与系统科学 2024-08-20 Zhenhuan Zhou , Along He , Yanlin Wu , Rui Yao , Xueshuo Xie , Tao Li

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

图像与视频处理 · 电气工程与系统科学 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

Image segmentation is pivotal in medical image analysis, facilitating clinical diagnosis, treatment planning, and disease evaluation. Deep learning has significantly advanced automatic segmentation methodologies by providing superior…

图像与视频处理 · 电气工程与系统科学 2026-01-22 Zhengyong Huang , Ning Jiang , Xingwen Sun , Lihua Zhang , Peng Chen , Jens Domke , Yao Sui

Accurate delineation of the intraprostatic gross tumour volume (GTV) is a prerequisite for treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific membrane antigen positron emission tomography (PSMA-PET) may…

Variability in staining protocols, such as different slide preparation techniques, chemicals, and scanner configurations, can result in a diverse set of whole slide images (WSIs). This distribution shift can negatively impact the…

图像与视频处理 · 电气工程与系统科学 2023-04-25 Kudaibergen Abutalip , Numan Saeed , Mustaqeem Khan , Abdulmotaleb El Saddik

Deep learning has become the de facto method for medical image segmentation, with 3D segmentation models excelling in capturing complex 3D structures and 2D models offering high computational efficiency. However, segmenting 2.5D images,…

图像与视频处理 · 电气工程与系统科学 2024-05-02 Amarjeet Kumar , Hongxu Jiang , Muhammad Imran , Cyndi Valdes , Gabriela Leon , Dahyun Kang , Parvathi Nataraj , Yuyin Zhou , Michael D. Weiss , Wei Shao

Prostate cancer (PCa) is a severe disease among men globally. It is important to identify PCa early and make a precise diagnosis for effective treatment. For PCa diagnosis, Multi-parametric magnetic resonance imaging (mpMRI) emerged as an…

图像与视频处理 · 电气工程与系统科学 2023-10-11 Anil B. Gavade , Neel Kanwal , Priyanka A. Gavade , Rajendra Nerli

Dose escalation radiotherapy allows increased control of prostate cancer (PCa) but requires segmentation of dominant index lesions (DIL), motivating the development of automated methods for fast, accurate, and consistent segmentation of PCa…

图像与视频处理 · 电气工程与系统科学 2023-03-08 Josiah Simeth , Jue Jiang , Anton Nosov , Andreas Wibmer , Michael Zelefsky , Neelam Tyagi , Harini Veeraraghavan
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