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Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

机器学习 · 计算机科学 2018-06-27 Anirban Mukhopadhyay

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

机器学习 · 统计学 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

Interpretable insights from predictive models remain critical in bio-statistics, particularly when assessing causality, where classical statistical and machine learning methods often provide inherent clarity. While Neural Networks (NNs)…

应用统计 · 统计学 2025-05-02 Jean-Baptiste A. Conan

Clinical decision making is challenging because of pathological complexity, as well as large amounts of heterogeneous data generated as part of routine clinical care. In recent years, machine learning tools have been developed to aid this…

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

With the spread and rapid advancement of black box machine learning models, the field of interpretable machine learning (IML) or explainable artificial intelligence (XAI) has become increasingly important over the last decade. This is…

Recent advancements in AI applications to healthcare have shown incredible promise in surpassing human performance in diagnosis and disease prognosis. With the increasing complexity of AI models, however, concerns regarding their opacity,…

机器学习 · 计算机科学 2023-08-17 Munib Mesinovic , Peter Watkinson , Tingting Zhu

This work proposes a fairness monitoring approach for machine learning models that predict patient mortality in the ICU. We investigate how well models perform for patient groups with different race, sex and medical diagnoses. We…

机器学习 · 计算机科学 2024-11-08 Tempest A. van Schaik , Xinggang Liu , Louis Atallah , Omar Badawi

Hypertension and atrial fibrillation (AF) often coexist in critically ill patients, significantly increasing mortality rates in the ICU. Early identification of high-risk individuals is crucial for targeted interventions. However, limited…

应用统计 · 统计学 2025-06-19 Shuheng Chen , Yong Si , Junyi Fan , Li Sun , Greg Placencia , Elham Pishgar , Kamiar Alaei , Maryam Pishgar

Deep learning methods have become very popular for the processing of natural images, and were then successfully adapted to the neuroimaging field. As these methods are non-transparent, interpretability methods are needed to validate them…

计算机视觉与模式识别 · 计算机科学 2022-04-15 Elina Thibeau-Sutre , Sasha Collin , Ninon Burgos , Olivier Colliot

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

机器学习 · 计算机科学 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Accurate patient mortality prediction enables effective risk stratification, leading to personalized treatment plans and improved patient outcomes. However, predicting mortality in healthcare remains a significant challenge, with existing…

机器学习 · 计算机科学 2025-03-28 HyeYoung Lee , Pavel Tsoi

The deployment of Large Language Models (LLMs) in high-stakes medical settings poses a critical AI alignment challenge, as models can inherit and amplify societal biases, leading to significant disparities. Existing fairness evaluation…

Pulmonary embolism (PE) is a leading cause of preventable in-hospital mortality. Advances in diagnosis, risk stratification, and prevention can improve outcomes. There are few large publicly available datasets that contain PE labels for…

计算与语言 · 计算机科学 2024-11-04 B. D. Lam , S. Ma , I. Kovalenko , P. Wang , O. Jafari , A. Li , S. Horng

Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

Deep neural networks have been well-known for their superb handling of various machine learning and artificial intelligence tasks. However, due to their over-parameterized black-box nature, it is often difficult to understand the prediction…

机器学习 · 计算机科学 2022-07-18 Xuhong Li , Haoyi Xiong , Xingjian Li , Xuanyu Wu , Xiao Zhang , Ji Liu , Jiang Bian , Dejing Dou

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

机器学习 · 计算机科学 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

Background: Hypertensive kidney disease (HKD) patients in intensive care units (ICUs) face high short-term mortality, but tailored risk prediction tools are lacking. Early identification of high-risk individuals is crucial for clinical…

机器学习 · 计算机科学 2025-07-28 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

人工智能 · 计算机科学 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

Background: The predictive Intensive Care Unit (ICU) scoring system plays an important role in ICU management because it predicts important outcomes, especially mortality. Many scoring systems have been developed and used in the ICU. These…

人工智能 · 计算机科学 2023-07-18 Mingquan Lin , Song Wang , Ying Ding , Lihui Zhao , Fei Wang , Yifan Peng