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In cardiac cells, structural organization is an important indicator of cell maturity and healthy function. Healthy cardiomyocytes exhibit well-aligned morphology with densely packed and organized sarcomeres. Immature or diseased…

定量方法 · 定量生物学 2025-02-03 Saeed Mohammadzadeh , Emma Lejeune

Timelapse images of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide rich information on cell structure and contractile function. However, it is challenging to reproducibly generate tissue samples and conduct…

定量方法 · 定量生物学 2025-11-18 Saeed Mohammadzadeh , Yao-Chang Tsan , Aaron Renberg , Hiba Kobeissi , Adam Helms , Emma Lejeune

Quantifying sarcomere structure organization in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is crucial for understanding cardiac disease pathology, improving drug screening, and advancing regenerative medicine.…

计算机视觉与模式识别 · 计算机科学 2024-10-29 Huyen Le , Khiet Dang , Tien Lai , Nhung Nguyen , Mai Tran , Hieu Pham

Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to regenerative tissue engineering. Yet, alongside these potential…

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a powerful tool in advancing cardiovascular research and clinical applications. The maturation of sarcomere organization in hiPSC-CMs is crucial, as it supports the…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Huyen Le , Khiet Dang , Nhung Nguyen , Mai Tran , Hieu Pham

Z-disks are complex structures that delineate repeating sarcomeres in striated muscle. They play significant roles in cardiomyocytes such as providing mechanical stability for the contracting sarcomere, cell signalling and autophagy.…

图像与视频处理 · 电气工程与系统科学 2024-01-25 Mihaela Croitor Ibrahim , Nishant Ravikumar , Alistair Curd , Joanna Leng , Oliver Umney , Michelle Peckham

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are an effective tool for studying cardiac function and disease, and hold promise for screening drug effects on human tissue. Changes to motion patterns in these cells…

组织与器官 · 定量生物学 2024-07-09 Henrik Finsberg , Verena Charwat , Kevin Healy , Samuel Wall

Cardiac segmentation of atriums, ventricles, and myocardium in computed tomography (CT) images is an important first-line task for presymptomatic cardiovascular disease diagnosis. In several recent studies, deep learning models have shown…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Sanguk Park , Minyoung Chung

Automated noninvasive cardiac diagnosis plays a critical role in the early detection of cardiac disorders and cost-effective clinical management. Automated diagnosis involves the automated segmentation and analysis of cardiac images.…

图像与视频处理 · 电气工程与系统科学 2025-04-21 Racheal Mukisa , Arvind K. Bansal

As medical imaging is central to diagnostic processes, automating the generation of radiology reports has become increasingly relevant to assist radiologists with their heavy workloads. Most current methods rely solely on global image…

计算机视觉与模式识别 · 计算机科学 2025-08-08 Hamza Kalisch , Fabian Hörst , Jens Kleesiek , Ken Herrmann , Constantin Seibold

Myocardial pathology segmentation (MyoPS) is critical for the risk stratification and treatment planning of myocardial infarction (MI). Multi-sequence cardiac magnetic resonance (MS-CMR) images can provide valuable information. For…

图像与视频处理 · 电气工程与系统科学 2023-02-08 Wangbin Ding , Lei Li , Junyi Qiu , Sihan Wang , Liqin Huang , Yinyin Chen , Shan Yang , Xiahai Zhuang

Accurate segmentation of cardiac structures in cardiovascular magnetic resonance (CMR) images is essential for reliable diagnosis and treatment of cardiovascular diseases. However, manual segmentation remains time-consuming and suffers from…

计算机视觉与模式识别 · 计算机科学 2026-04-07 Ujjwal Jain

The prevailing deep learning-based methods of predicting cardiac segmentation involve reconstructed magnetic resonance (MR) images. The heavy dependency of segmentation approaches on image quality significantly limits the acceleration rate…

图像与视频处理 · 电气工程与系统科学 2025-07-03 Yundi Zhang , Nil Stolt-Ansó , Jiazhen Pan , Wenqi Huang , Kerstin Hammernik , Daniel Rueckert

The segmentation and classification of cardiac magnetic resonance imaging are critical for diagnosing heart conditions, yet current approaches face challenges in accuracy and generalizability. In this study, we aim to further advance the…

图像与视频处理 · 电气工程与系统科学 2024-12-13 Vitalii Slobodzian , Pavlo Radiuk , Oleksander Barmak , Iurii Krak

Current artificial intelligence (AI) algorithms for short-axis cardiac magnetic resonance (CMR) segmentation achieve human performance for slices situated in the middle of the heart. However, an often-overlooked fact is that segmentation of…

图像与视频处理 · 电气工程与系统科学 2021-09-21 Jorge Mariscal-Harana , Naomi Kifle , Reza Razavi , Andrew P. King , Bram Ruijsink , Esther Puyol-Antón

Cardiac magnetic resonance imaging (MRI) is a pivotal tool for assessing cardiac function. Precise segmentation of cardiac structures is imperative for accurate cardiac functional evaluation. This paper introduces a semi-supervised model…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Hejun Huang , Zuguo Chen , Yi Huang , Guangqiang Luo , Chaoyang Chen , Youzhi Song

Cardiac magnetic resonance imaging improves on diagnosis of cardiovascular diseases by providing images at high spatiotemporal resolution. Manual evaluation of these time-series, however, is expensive and prone to biased and…

计算机视觉与模式识别 · 计算机科学 2018-04-06 Fabian Isensee , Paul Jaeger , Peter M. Full , Ivo Wolf , Sandy Engelhardt , Klaus H. Maier-Hein

One of the challenges in developing deep learning algorithms for medical image segmentation is the scarcity of annotated training data. To overcome this limitation, data augmentation and semi-supervised learning (SSL) methods have been…

图像与视频处理 · 电气工程与系统科学 2020-09-02 Bram Ruijsink , Esther Puyol-Anton , Ye Li , Wenja Bai , Eric Kerfoot , Reza Razavi , Andrew P. King

Precise and effective processing of cardiac imaging data is critical for the identification and management of the cardiovascular diseases. We introduce IntelliCardiac, a comprehensive, web-based medical image processing platform for the…

The amount of fat on the surroundings of the heart is correlated to several health risk factors such as carotid stiffness, coronary artery calcification, atrial fibrillation, atherosclerosis, cancer incidence and others. Furthermore, the…

计算机视觉与模式识别 · 计算机科学 2026-05-29 É. O. Rodrigues , A. Conci , F. F. C. Morais , M. G. Pérez
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