相关论文: Adversarial Contrastive Pre-training for Protein S…

Recent work has demonstrated that deep neural networks are vulnerable to adversarial examples---inputs that are almost indistinguishable from natural data and yet classified incorrectly by the network. In fact, some of the latest findings…

The remarkable success of pretrained language models has motivated the study of what kinds of knowledge these models learn during pretraining. Reformulating tasks as fill-in-the-blanks problems (e.g., cloze tests) is a natural approach for…

Antibodies are vital proteins offering robust protection for the human body from pathogens. The development of general protein and antibody-specific pre-trained language models both facilitate antibody prediction tasks. However, there have…

Geometric deep learning has recently achieved great success in non-Euclidean domains, and learning on 3D structures of large biomolecules is emerging as a distinct research area. However, its efficacy is largely constrained due to the…

Protein Language Models (PLMs), pre-trained on extensive evolutionary data from natural proteins, have emerged as indispensable tools for protein design. While powerful, PLMs often struggle to produce proteins with precisely specified…

Large Language Models (LLMs) have transformed the natural language processing landscape and brought to life diverse applications. Pretraining on vast web-scale data has laid the foundation for these models, yet the research community is now…

This paper demonstrates that language models are strong structure-based protein designers. We present LM-Design, a generic approach to reprogramming sequence-based protein language models (pLMs), that have learned massive sequential…

In this paper, we study a new learning paradigm for Neural Machine Translation (NMT). Instead of maximizing the likelihood of the human translation as in previous works, we minimize the distinction between human translation and the…

Masked language modeling (MLM) has been widely used for pre-training effective bidirectional representations, but incurs substantial training costs. In this paper, we propose a novel concept-based curriculum masking (CCM) method to…

In this work, we provide a survey of active learning (AL) for its applications in natural language processing (NLP). In addition to a fine-grained categorization of query strategies, we also investigate several other important aspects of…

Distributed representations of words which map each word to a continuous vector have proven useful in capturing important linguistic information not only in a single language but also across different languages. Current unsupervised…

Natural language processing (NLP) enables the understanding and generation of meaningful human language, typically using a pre-trained complex architecture on a large dataset to learn the language and next fine-tune its weights to implement…

Understanding biological processes, drug development, and biotechnological advancements requires a detailed analysis of protein structures and functions, a task that is inherently complex and time-consuming in traditional protein research.…

The field of chemistry and Artificial Intelligence (AI) intersection is an area of active research that aims to accelerate scientific discovery. The integration of large language models (LLMs) with scientific modalities has shown…

The surge of state-of-the-art Transformer-based models has undoubtedly pushed the limits of NLP model performance, excelling in a variety of tasks. We cast the spotlight on the underexplored task of Natural Language Inference (NLI), since…

Deep learning-based Natural Language Processing methods, especially transformers, have achieved impressive performance in the last few years. Applying those state-of-the-art NLP methods to legal activities to automate or simplify some…

Computational protein-protein interaction (PPI) prediction techniques can contribute greatly in reducing time, cost and false-positive interactions compared to experimental approaches. Sequence is one of the key and primary information of…

Pre-trained language models learn informative word representations on a large-scale text corpus through self-supervised learning, which has achieved promising performance in fields of natural language processing (NLP) after fine-tuning.…

Natural Language Processing (NLP) is widely used in fields like machine translation and sentiment analysis. However, traditional NLP models struggle with accuracy and efficiency. This paper introduces Deep Convolutional Neural Networks…

In the past few years, the emergence of pre-training models has brought uni-modal fields such as computer vision (CV) and natural language processing (NLP) to a new era. Substantial works have shown they are beneficial for downstream…