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相关论文: A Petri Dish for Histopathology Image Analysis

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Single-cell transcriptomics and proteomics have become a great source for data-driven insights into biology, enabling the use of advanced deep learning methods to understand cellular heterogeneity and gene expression at the single-cell…

基因组学 · 定量生物学 2025-12-15 Hiren Madhu , João Felipe Rocha , Tinglin Huang , Siddharth Viswanath , Smita Krishnaswamy , Rex Ying

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Histological staining is a vital step used to diagnose various diseases and has been used for more than a century to provide contrast to tissue sections, rendering the tissue constituents visible for microscopic analysis by medical experts.…

图像与视频处理 · 电气工程与系统科学 2020-05-08 Yijie Zhang , Kevin de Haan , Yair Rivenson , Jingxi Li , Apostolos Delis , Aydogan Ozcan

Multiple instance learning (MIL) has enabled substantial progress in computational histopathology, where a large amount of patches from gigapixel whole slide images are aggregated into slide-level predictions. Heatmaps are widely used to…

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet…

计算机视觉与模式识别 · 计算机科学 2026-01-26 Peixian Liang , Songhao Li , Shunsuke Koga , Yutong Li , Zahra Alipour , Yucheng Tang , Daguang Xu , Zhi Huang

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

计算机视觉与模式识别 · 计算机科学 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

High-resolution and variable-shape images have not yet been properly addressed by the AI community. The approach of down-sampling data often used with convolutional neural networks is sub-optimal for many tasks, and has too many drawbacks…

计算机视觉与模式识别 · 计算机科学 2020-09-30 Ferran Parés , Dario Garcia-Gasulla , Harald Servat , Jesús Labarta , Eduard Ayguadé

Microsatellite instability (MSI) is a tumor phenotype whose diagnosis largely impacts patient care in colorectal cancers (CRC), and is associated with response to immunotherapy in all solid tumors. Deep learning models detecting MSI tumors…

图像与视频处理 · 电气工程与系统科学 2022-03-23 Charlie Saillard , Olivier Dehaene , Tanguy Marchand , Olivier Moindrot , Aurélie Kamoun , Benoit Schmauch , Simon Jegou

Computational analysis of whole slide images (WSIs) has seen significant research progress in recent years, with applications ranging across important diagnostic and prognostic tasks such as survival or cancer subtype prediction. Many…

计算机视觉与模式识别 · 计算机科学 2024-11-28 Zak Buzzard , Konstantin Hemker , Nikola Simidjievski , Mateja Jamnik

Accurate assessment of dietary intake requires improved tools to overcome limitations of current methods including user burden and measurement error. Emerging technologies such as image-based approaches using advanced machine learning…

计算机视觉与模式识别 · 计算机科学 2021-10-06 Zeman Shao , Yue Han , Jiangpeng He , Runyu Mao , Janine Wright , Deborah Kerr , Carol Boushey , Fengqing Zhu

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

Cancer diagnosis has greatly benefited from the integration of whole-slide images (WSIs) with multiple instance learning (MIL), enabling high-resolution analysis of tissue morphology. Graph-based MIL (GNN-MIL) approaches have emerged as…

计算机视觉与模式识别 · 计算机科学 2025-08-27 Jongwoo Kim , Bryan Wong , Huazhu Fu , Willmer Rafell Quiñones , Youngsin Ko , Mun Yong Yi

Recognizing handwritten digits is a challenging task primarily due to the diversity of writing styles and the presence of noisy images. The widely used MNIST dataset, which is commonly employed as a benchmark for this task, includes…

计算机视觉与模式识别 · 计算机科学 2023-07-28 Amarnath R , Vinay Kumar

Digital pathology involves converting physical tissue slides into high-resolution Whole Slide Images (WSIs), which pathologists analyze for disease-affected tissues. However, large histology slides with numerous microscopic fields pose…

图像与视频处理 · 电气工程与系统科学 2024-02-19 Mobina Mansoori , Sajjad Shahabodini , Jamshid Abouei , Arash Mohammadi , Konstantinos N. Plataniotis

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

计算机视觉与模式识别 · 计算机科学 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

计算机视觉与模式识别 · 计算机科学 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Pathology images of histopathology can be acquired from camera-mounted microscopes or whole slide scanners. Utilizing similarity calculations to match patients based on these images holds significant potential in research and clinical…

图像与视频处理 · 电气工程与系统科学 2024-03-25 H. R. Tizhoosh , Liron Pantanowitz

Whole slide pathology image classification presents challenges due to gigapixel image sizes and limited annotation labels, hindering model generalization. This paper introduces a prompt learning method to adapt large vision-language models…

In recent years, deep learning has successfully been applied to automate a wide variety of tasks in diagnostic histopathology. However, fast and reliable localization of small-scale regions-of-interest (ROI) has remained a key challenge, as…

图像与视频处理 · 电气工程与系统科学 2022-01-06 Jon Braatz , Pranav Rajpurkar , Stephanie Zhang , Andrew Y. Ng , Jeanne Shen

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

计算机视觉与模式识别 · 计算机科学 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He