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In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

机器学习 · 计算机科学 2016-11-17 Chris Roadknight , Uwe Aickelin , Guoping Qiu , John Scholefield , Lindy Durrant

Advance in medical imaging is an important part in deep learning research. One of the goals of computer vision is development of a holistic, comprehensive model which can identify tumors from histology slides obtained via biopsies. A major…

图像与视频处理 · 电气工程与系统科学 2024-12-18 Vidit Gautam

Tissue segmentation is an important pre-requisite for efficient and accurate diagnostics in digital pathology. However, it is well known that whole-slide scanners can fail in detecting all tissue regions, for example due to the tissue type,…

计算机视觉与模式识别 · 计算机科学 2017-04-04 Péter Bándi , Rob van de Loo , Milad Intezar , Daan Geijs , Francesco Ciompi , Bram van Ginneken , Jeroen van der Laak , Geert Litjens

Label-free cell classification is advantageous for supplying pristine cells for further use or examination, yet existing techniques frequently fall short in terms of specificity and speed. In this study, we address these limitations through…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Khayrul Islam , Ratul Paul , Shen Wang , Yuwen Zhao , Partho Adhikary , Qiying Li , Xiaochen Qin , Yaling Liu

With the development of computer technology, various models have emerged in artificial intelligence. The transformer model has been applied to the field of computer vision (CV) after its success in natural language processing (NLP).…

计算机视觉与模式识别 · 计算机科学 2022-07-05 Ruina Sun , Yuexin Pang

Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology may help us to…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Yi Cui , Yao Li , Jayson R. Miedema , Sharon N. Edmiston , Sherif Farag , J. S. Marron , Nancy E. Thomas

With the long-term rapid increase in incidences of colorectal cancer (CRC), there is an urgent clinical need to improve risk stratification. The conventional pathology report is usually limited to only a few histopathological features.…

图像与视频处理 · 电气工程与系统科学 2020-07-08 Christian Abbet , Inti Zlobec , Behzad Bozorgtabar , Jean-Philippe Thiran

Pathology slides of lung malignancies are classified using resource-frugal convolution neural networks (CNNs) that may be deployed on mobile devices. In particular, the challenging task of distinguishing adenocarcinoma (LUAD) and…

图像与视频处理 · 电气工程与系统科学 2021-03-26 Steven J. Frank

This paper addresses the problem of liver cancer segmentation in Whole Slide Image (WSI). We propose a multi-scale image processing method based on automatic end-to-end deep neural network algorithm for segmentation of cancer area. A…

图像与视频处理 · 电气工程与系统科学 2020-07-29 Yanbo Feng , Adel Hafiane , Hélène Laurent

Early tumor detection save lives. Each year, more than 300 million computed tomography (CT) scans are performed worldwide, offering a vast opportunity for effective cancer screening. However, detecting small or early-stage tumors on these…

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Tumor growth is associated with cell invasion and mass-effect, which are traditionally formulated by mathematical models, namely reaction-diffusion equations and biomechanics. Such models can be personalized based on clinical measurements…

计算机视觉与模式识别 · 计算机科学 2018-01-26 Ling Zhang , Le Lu , Ronald M. Summers , Electron Kebebew , Jianhua Yao

Computed tomography (CT) and clinical numeric data are essential modalities for cancer evaluation, but building large-scale multimodal training datasets for developing medical foundation models remains challenging due to the structural…

计算机视觉与模式识别 · 计算机科学 2025-01-24 Daeun Jung , Jaehyeok Jang , Sooyoung Jang , Yu Rang Park

Survival of living tumor cells underlies many influences such as nutrient saturation, oxygen level, drug concentrations or mechanical forces. Data-supported mathematical modeling can be a powerful tool to get a better understanding of cell…

Large variability between cell lines brings a difficult optimization problem of drug selection for cancer therapy. Standard approaches use prediction of value for this purpose, corresponding e.g. to expected value of their distribution.…

定量方法 · 定量生物学 2022-09-15 Jarek Duda

The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…

定量方法 · 定量生物学 2021-09-21 Pingjun Chen , Muhammad Aminu , Siba El Hussein , Joseph D. Khoury , Jia Wu

The use of mathematical models to make predictions about tumor growth and response to treatment has become increasingly more prevalent in the clinical setting. The level of complexity within these models ranges broadly, and the calibration…

定量方法 · 定量生物学 2021-12-28 Allison L. Lewis , Kathleen M. Storey , Heyrim Cho , Anna C. Zittle

Deep Neural Networks have shown promising classification performance when predicting certain biomarkers from Whole Slide Images in digital pathology. However, the calibration of the networks' output probabilities is often not evaluated.…

图像与视频处理 · 电气工程与系统科学 2023-12-18 Alexander Kurz , Hendrik A. Mehrtens , Tabea-Clara Bucher , Titus J. Brinker

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

机器学习 · 计算机科学 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

图像与视频处理 · 电气工程与系统科学 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena
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