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This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The framework, termed generative discriminative machine (GDM),…

应用统计 · 统计学 2019-06-04 Erdem Varol , Aristeidis Sotiras , Ke Zeng , Christos Davatzikos

The development of diagnostic models is gaining traction in the field of psychiatric disorders. Recently, machine learning classifiers based on resting-state functional magnetic resonance imaging (rs-fMRI) have been developed to identify…

机器学习 · 计算机科学 2025-10-06 Tianzheng Hu , Qiang Li , Shu Liu , Vince D. Calhoun , Guido van Wingen , Shujian Yu

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

The integration of multi-modal Magnetic Resonance Imaging (MRI) and clinical data holds great promise for enhancing the diagnosis of neurological disorders (NDs) in real-world clinical settings. Deep Learning (DL) has recently emerged as a…

图像与视频处理 · 电气工程与系统科学 2025-06-19 Wajih Hassan Raza , Aamir Bader Shah , Yu Wen , Yidan Shen , Juan Diego Martinez Lemus , Mya Caryn Schiess , Timothy Michael Ellmore , Renjie Hu , Xin Fu

Studies on schizophrenia assessments using deep learning typically treat it as a classification task to detect the presence or absence of the disorder, oversimplifying the condition and reducing its clinical applicability. This traditional…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Gowtham Premananth , Philip Resnik , Sonia Bansal , Deanna L. Kelly , Carol Espy-Wilson

Deep learning approaches, together with neuroimaging techniques, play an important role in psychiatric disorders classification. Previous studies on psychiatric disorders diagnosis mainly focus on using functional connectivity matrices of…

图像与视频处理 · 电气工程与系统科学 2023-10-05 Guoxin Wang , Xuyang Cao , Shan An , Fengmei Fan , Chao Zhang , Jinsong Wang , Feng Yu , Zhiren Wang

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Schizophrenia is a severe mental health condition that requires a long and complicated diagnostic process. However, early diagnosis is vital to control symptoms. Deep learning has recently become a popular way to analyse and interpret…

机器学习 · 计算机科学 2022-04-01 Daniel Organisciak , Hubert P. H. Shum , Ephraim Nwoye , Wai Lok Woo

Recent neuroimaging studies that focus on predicting brain disorders via modern machine learning approaches commonly include a single modality and rely on supervised over-parameterized models.However, a single modality provides only a…

Smart systems that can accurately diagnose patients with mental disorders and identify effective treatments based on brain functional imaging data are of great applicability and are gaining much attention. Most previous machine learning…

计算机视觉与模式识别 · 计算机科学 2017-12-05 Jumana Dakka , Pouya Bashivan , Mina Gheiratmand , Irina Rish , Shantenu Jha , Russell Greiner

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

图像与视频处理 · 电气工程与系统科学 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

We present a foundation model for brain MRI that can work with different combinations of imaging sequences. The model uses one encoder with learnable modality embeddings, conditional layer normalization, and a masked autoencoding objective…

计算机视觉与模式识别 · 计算机科学 2025-11-06 Minh Sao Khue Luu , Bair N. Tuchinov

Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…

机器学习 · 计算机科学 2025-08-06 Tatwadarshi P Nagarhalli , Sanket Patil , Vishal Pande , Uday Aswalekar , Prafulla Patil

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li

As shown in computer vision, the power of deep learning lies in automatically learning relevant and powerful features for any perdition task, which is made possible through end-to-end architectures. However, deep learning approaches applied…

计算机视觉与模式识别 · 计算机科学 2018-10-02 Soheil Esmaeilzadeh , Dimitrios Ioannis Belivanis , Kilian M. Pohl , Ehsan Adeli

Both functional and structural magnetic resonance imaging (fMRI and sMRI) are widely used for the diagnosis of mental disorder. However, combining complementary information from these two modalities is challenging due to their…

图像与视频处理 · 电气工程与系统科学 2024-04-02 Ziyu Zhou , Anton Orlichenko , Gang Qu , Zening Fu , Vince D Calhoun , Zhengming Ding , Yu-Ping Wang

Automatic segmentation of brain glioma from multimodal MRI scans plays a key role in clinical trials and practice. Unfortunately, manual segmentation is very challenging, time-consuming, costly, and often inaccurate despite human expertise…

图像与视频处理 · 电气工程与系统科学 2020-12-08 Minh H. Vu , Tufve Nyholm , Tommy Löfstedt

Finding the biomarkers associated with ASD is helpful for understanding the underlying roots of the disorder and can lead to earlier diagnosis and more targeted treatment. A promising approach to identify biomarkers is using Graph Neural…

机器学习 · 计算机科学 2019-07-15 Xiaoxiao Li , Nicha C. Dvornek , Yuan Zhou , Juntang Zhuang , Pamela Ventola , James S. Duncan
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