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For many complex diseases, prognosis is of essential importance. It has been shown that, beyond the main effects of genetic (G) and environmental (E) risk factors, the gene-environment (G$\times$E) interactions also play a critical role. In…

应用统计 · 统计学 2015-05-15 Hao Chai , Qingzhao Zhang , Yu Jiang , Guohua Wang , Sanguo Zhang , Shuangge Ma

Several modern applications require the integration of multiple large data matrices that have shared rows and/or columns. For example, cancer studies that integrate multiple omics platforms across multiple types of cancer, pan-omics…

机器学习 · 统计学 2022-04-08 Eric F. Lock , Jun Young Park , Katherine A. Hoadley

Augmenting randomized controlled trials (RCTs) with external real-world data (RWD) has the potential to improve the finite sample efficiency of treatment effect estimators. We describe using adaptive targeted maximum likelihood estimation…

统计方法学 · 统计学 2025-01-30 Sky Qiu , Jens Tarp , Andrew Mertens , Mark van der Laan

Root cause analysis is one of the most crucial operations in software reliability regarding system performance diagnostic. It aims to identify the root causes of system performance anomalies, allowing the resolution or the future prevention…

软件工程 · 计算机科学 2025-01-22 Andrea Tonon , Meng Zhang , Bora Caglayan , Fei Shen , Tong Gui , MingXue Wang , Rong Zhou

Anomaly detection in MRI is of high clinical value in imaging and diagnosis. Unsupervised methods for anomaly detection provide interesting formulations based on reconstruction or latent embedding, offering a way to observe properties…

图像与视频处理 · 电气工程与系统科学 2022-11-29 Ayantika Das , Arun Palla , Keerthi Ram , Mohanasankar Sivaprakasam

Cancer subtype classification is crucial for personalized treatment and prognostic assessment. However, effectively integrating multi-omic data remains challenging due to the heterogeneous nature of genomic, epigenomic, and transcriptomic…

机器学习 · 计算机科学 2025-06-10 Sajib Acharjee Dip , Uddip Acharjee Shuvo , Dipanwita Mallick , Abrar Rahman Abir , Liqing Zhang

The integration of data from multiple sources is increasingly used to achieve larger sample sizes and enhance population diversity. Our previous work established that, under random sampling from the same underlying population, integrating…

统计方法学 · 统计学 2026-01-01 Farimah Shamsi , Andriy Derkach

Deceptive reviews, refer to fabricated feedback designed to artificially manipulate the perceived quality of products. Within modern e-commerce ecosystems, these reviews remain a critical governance challenge. Despite advances in…

信息检索 · 计算机科学 2026-05-08 Nan Lu , Leyang Li , Yurong Hu , Rui Lin , Shaoyi Xu

Matrix decomposition is one of the fundamental tools to discover knowledge from big data generated by modern applications. However, it is still inefficient or infeasible to process very big data using such a method in a single machine.…

机器学习 · 计算机科学 2020-02-11 Chihao Zhang , Yang Yang , Wei Zhang , Shihua Zhang

The singular value decomposition is widely used to approximate data matrices with lower rank matrices. Feng and He [Ann. Appl. Stat. 3 (2009) 1634-1654] developed tests on dimensionality of the mean structure of a data matrix based on the…

统计理论 · 数学 2014-02-28 Xingdong Feng , Xuming He

Inference networks of traditional Variational Autoencoders (VAEs) are typically amortized, resulting in relatively inaccurate posterior approximation compared to instance-wise variational optimization. Recent semi-amortized approaches were…

机器学习 · 计算机科学 2020-11-18 Minyoung Kim , Vladimir Pavlovic

Identifying root causes of anomalies in causal processes is vital across disciplines. Once identified, one can isolate the root causes and implement necessary measures to restore the normal operation. Causal processes are often modelled as…

人工智能 · 计算机科学 2023-12-20 Phuoc Nguyen , Truyen Tran , Sunil Gupta , Thin Nguyen , Svetha Venkatesh

Two key tasks in high-dimensional regularized regression are tuning the regularization strength for accurate predictions and estimating the out-of-sample risk. It is known that the standard approach -- $k$-fold cross-validation -- is…

统计理论 · 数学 2025-10-24 Kevin Luo , Yufan Li , Pragya Sur

Cross-Domain Recommendation (CDR) seeks to enable effective knowledge transfer across domains. Existing works rely on either representation alignment or transformation bridges, but they struggle on identifying domain-shared from…

信息检索 · 计算机科学 2024-04-09 Jing Du , Zesheng Ye , Bin Guo , Zhiwen Yu , Lina Yao

Modern data augmentation using a mixture-based technique can regularize the models from overfitting to the training data in various computer vision applications, but a proper data augmentation technique tailored for the part-based…

计算机视觉与模式识别 · 计算机科学 2023-04-05 Minsu Kim , Seungryong Kim , JungIn Park , Seongheon Park , Kwanghoon Sohn

Jointly extracting entity pairs and their relations is challenging when working on distantly-supervised data with ambiguous or noisy labels. To mitigate such impact, we propose uncertainty-aware bootstrap learning, which is motivated by the…

计算与语言 · 计算机科学 2023-06-12 Yufei Li , Xiao Yu , Yanchi Liu , Haifeng Chen , Cong Liu

Federated or multi-site studies have distinct advantages over single-site studies, including increased generalizability, the ability to study underrepresented populations, and the opportunity to study rare exposures and outcomes. However,…

机器学习 · 统计学 2023-09-25 Larry Han , Zhu Shen , Jose Zubizarreta

Cellwise outliers are likely to occur together with casewise outliers in modern data sets with relatively large dimension. Recent work has shown that traditional robust regression methods may fail for data sets in this paradigm. The…

统计理论 · 数学 2016-12-28 Andy Leung , Hongyang Zhang , Ruben H. Zamar

Nowadays, how to effectively evaluate visual properties has become a popular topic for fine-grained visual comprehension. In this paper we study the problem of how to estimate such visual properties from a ranking perspective with the help…

统计方法学 · 统计学 2021-01-19 Qianqian Xu , Jiechao Xiong , Xiaochun Cao , Qingming Huang , Yuan Yao

The presence of outliers (anomalous values) in synthetic aperture radar (SAR) data and the misspecification in statistical image models may result in inaccurate inferences. To avoid such issues, the Rayleigh regression model based on a…

应用统计 · 统计学 2022-08-02 B. G. Palm , F. M. Bayer , R. Machado , M. I. Pettersson , V. T. Vu , R. J. Cintra