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Given that there are 94 clinics and more than 200,000 patients treated worldwide, proton and carbon are the most used heavily charged particles in heavy ion therapy. However, there is a recent increasing trend in using new ion beams. Each…

医学物理 · 物理学 2021-01-26 Fatih Ekinci , Erkan Bostanci , Ozlem Dagli , Mehmet Serdar Guzel

This comprehensive study delves into the intricate interplay between protons and organic polymers, offering insights into proton therapy in cancer treatment. Focusing on the influence of the spatial electron density distribution on stopping…

Proton therapy offers significant advantages due to its unique physical and biological properties, particularly the Bragg peak, enabling precise dose delivery to tumors while sparing healthy tissues. However, the clinical implementation is…

We used the GEANT4 Monte Carlo MC Toolkit to simulate carbon ion beams incident on water, tissue, and bone, taking into account nuclear fragmentation reactions. Upon increasing the energy of the primary beam, the position of the Bragg-Peak…

医学物理 · 物理学 2021-02-26 M. Kh. Hamad

Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research.…

Proton beam radiotherapy stands at the forefront of precision cancer treatment, leveraging the unique physical interactions of proton beams with human tissue to deliver minimal dose upon entry and deposit the therapeutic dose precisely at…

Photons are exponentially attenuated in matter producing high doses close to the surface. Therefore they are not well suited for the treatment of deep seated tumours. Charged particles, in contrast, exhibit a sharp increase of ionisation…

仪器与探测器 · 物理学 2009-11-06 C. Grupen

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

The energy loss and energy loss straggling widths have been measured in transmission for MeV protons traversing a thin kapton polyimide foil. In a prior step, the thickness and non-uniformity of the target foil were carefully investigated.…

仪器与探测器 · 物理学 2017-09-20 S. Damache , S. Djaroum , S. Ouichaoui , L. Amari , D. Moussa

The carbon beams show more advantages on the biological properties compared with proton beams in radiation therapy. The carbon beam shows high linear energy transfer (LET) to medium and it increases the relative biological effectiveness…

230 MeV proton beam out of a cyclotron was delivered into a Zebra multi layered IC detector (IBA) calibrated in terms of penetration range in water. The analysis of the measured Bragg peak determines penetration range in water which can be…

医学物理 · 物理学 2017-07-27 Vladimir Anferov , Vladimir Derenchuck , Ron Moore , Andreas Schreuder

For the assessment of radiation effects of clinical ion-beams, dosimetry has to be complemented by information on particle-energy distribution or related quantities. Fluorescence nuclear track detectors made from C,Mg-doped alumina single…

医学物理 · 物理学 2017-09-22 Steffen Greilich , Leonie Ulrich , Jasper J. M. Kouwenberg , Shirin Rahmanian

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

This study aims to assess the composition of scattered particles generated in proton therapy for tumours situated proximal to titanium dental implants. The investigation involves decomposing the mixed field and recording Linear Energy…

We have measured the electronic energy-loss straggling of protons, helium, boron and silicon ions in silicon using a transmission time-of-flight approach. Ions with velocities between 0.25 and 1.6 times the Bohr velocity were transmitted…

材料科学 · 物理学 2023-02-08 Svenja Lohmann , Radek Holeňák , Pedro L. Grande , Daniel Primetzhofer

The conventional treatment of the Bethe-Bloch equation for protons accounts for electron capture at the end of the projectile track by the small Barkas correction. This is only a possible way for protons, whereas for light and heavier…

医学物理 · 物理学 2011-09-13 W. Ulmer

Proton therapy can achieve a highly targeted treatment by utilising the advantageous dosimetric characteristics of the Bragg Peak. Protons traversing through a material will deposit their maximum energy at the Bragg Peak through ionisation…

The electronic stopping power ($S_e$) of water vapor (H$_2$O), hydrogen (H$_2$) and oxygen (O$_2$) gases for protons in a broad range of energies, centered in the Bragg peak, was calculated using real-time time-dependent density functional…

Carbon-ion radiotherapy (CIRT) is generally evaluated with the dose weighted by relative biological effectiveness (RBE), while the radiation quality varying in the body of each patient is ignored for lack of such distribution. In this…

医学物理 · 物理学 2018-05-30 Nobuyuki Kanematsu , Naruhiro Matsufuji , Taku Inaniwa

By means of a time-of-flight technique, we measured the longitudinal profile of prompt $\gamma$-rays emitted by 73 MeV/u $^{13}$C ions irradiating a PMMA target. This technique allowed us to minimize the shielding against neutrons and…

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