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Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

计算机视觉与模式识别 · 计算机科学 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

A resolution enhancement technique for optical coherence tomography (OCT), based on Generative Adversarial Networks (GANs), was developed and investigated. GANs have been previously used for resolution enhancement of photography and optical…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Kaicheng Liang , Xinyu Liu , Si Chen , Jun Xie , Wei Qing Lee , Linbo Liu , Hwee Kuan Lee

Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As a consequence, OCT is susceptible to coherent noise (speckle…

Optical Coherence Tomography Angiography (OCTA) is a non-invasive and non-contacting imaging technique providing visualization of microvasculature of retina and optic nerve head in human eyes in vivo. The adequate image quality of OCTA is…

图像与视频处理 · 电气工程与系统科学 2021-07-23 Yufei Wang , Yiqing Shen , Meng Yuan , Jing Xu , Bin Yang , Chi Liu , Wenjia Cai , Weijing Cheng , Wei Wang

Acousto-optical coherence tomography (AOCT) consists in using random phase jumps on ultrasound and light to achieve a millimeter resolution when imaging thick scattering media. We combined this technique with heterodyne off-axis digital…

光学 · 物理学 2012-10-12 Michel Gross , François Ramaz , Emilie Benoit , Emmanuel Bossy , Salma Farahi

Optical coherence tomography angiography (OCTA) has been established as a powerful tool for investigating vascular diseases and is expected to become a standard of care technology. However, its widespread clinical usage is hindered by…

医学物理 · 物理学 2021-09-10 Si Chen , Kan Lin , Linbo Liu

Purpose: This study explores the feasibility of using generative machine learning (ML) to translate Optical Coherence Tomography (OCT) images into Optical Coherence Tomography Angiography (OCTA) images, potentially bypassing the need for…

计算机视觉与模式识别 · 计算机科学 2024-04-26 Rashadul Hasan Badhon , Atalie Carina Thompson , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam

Quantum optical coherence tomography (QOCT) offers a simple way to cancel dispersion broadening in a sample while also providing twice the resolution compared to classical OCT. However, to achieve these advantages, a bright and broadband…

量子物理 · 物理学 2025-12-15 Anna Romanova , Vadim Rodimin , Konstantin Katamadze

Optical coherence tomography (OCT) is capable of non-destructively obtaining cross-sectional information of samples with micrometer spatial resolution, which plays an important role in ophthalmology and endovascular medicine. Measuring OCT…

医学物理 · 物理学 2023-11-30 Yang Jianlong , Zhang Haoran , Liu Chang , Gu Chengfu

We present a general theory of optical coherence tomography (OCT), which synthesizes the fundamental concepts and implementations of OCT under a common 3D k-space framework. At the heart of this analysis is the Fourier diffraction theorem,…

光学 · 物理学 2021-06-28 Kevin C. Zhou , Ruobing Qian , Al-Hafeez Dhalla , Sina Farsiu , Joseph A. Izatt

This work compares two tomographic imaging technologies, time-domain full-field optical coherence tomography (FFOCT) working in reflection and optical transmission tomography (OTT), using a new optical setup that combines both. We show…

Mid-infrared light scatters much less than shorter wavelengths, allowing greatly enhanced penetration depths for optical imaging techniques such as optical coherence tomography (OCT). However, both detection and broadband sources in the…

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

数值分析 · 数学 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Spectral domain optical coherence tomography (OCT) offers high resolution multidimensional imaging, but generally suffers from defocussing, intensity falloff and shot noise, causing artifacts and image degradation along the imaging depth.…

图像与视频处理 · 电气工程与系统科学 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

医学物理 · 物理学 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in…

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…

医学物理 · 物理学 2020-05-29 Cerine Lal , Sergey Alexandrov , Sweta Rani , Yi Zhou , Thomas Ritter , Martin Leahy

Conventional Fourier-domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into wavenumber (k) domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing…

光学 · 物理学 2025-09-24 Maryam Viqar , Erdem Sahin , Elena Stoykova , Violeta Madjarova

Speckle is an intrinsic pattern in optical coherence tomography (OCT) that obscures fine image features and degrades effective resolution. In this study, we propose a numerical speckle reduction method based on the dispersed scatterer model…