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The preponderance of large-scale healthcare databases provide abundant opportunities for comparative effectiveness research. Evidence necessary to making informed treatment decisions often relies on comparing effectiveness of multiple…

统计方法学 · 统计学 2020-10-06 Liangyuan Hu , Chenyang Gu

Understanding and inferencing Heterogeneous Treatment Effects (HTE) and Conditional Average Treatment Effects (CATE) are vital for developing personalized treatment recommendations. Many state-of-the-art approaches achieve inspiring…

机器学习 · 计算机科学 2024-08-28 Chan Hsu , Jun-Ting Wu , Yihuang Kang

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

计算机视觉与模式识别 · 计算机科学 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

As a multitude of capable machine learning (ML) models become widely available in forms such as open-source software and public APIs, central questions remain regarding their use in real-world applications, especially in high-stakes…

机器学习 · 计算机科学 2024-06-03 Dimitris Bertsimas , Matthew Peroni

B2B sales organizations must identify "persuadable" accounts within zero-inflated revenue distributions to optimize expensive human resource allocation. Standard uplift frameworks struggle with treatment signal collapse in high-dimensional…

机器学习 · 计算机科学 2026-04-06 Vamshi Guduguntla , Kavin Soni , Debanshu Das

Curating a large scale medical imaging dataset for machine learning applications is both time consuming and expensive. Balancing the workload between model development, data collection and annotations is difficult for machine learning…

人工智能 · 计算机科学 2022-06-07 Athanasios Vlontzos , Hadrien Reynaud , Bernhard Kainz

Uplift modeling aims to estimate the treatment effect on individuals, widely applied in the e-commerce platform to target persuadable customers and maximize the return of marketing activities. Among the existing uplift modeling methods,…

机器学习 · 计算机科学 2023-03-07 Chang Sun , Qianying Li , Guanxiang Wang , Sihao Xu , Yitong Liu

Most data for evaluating and training recommender systems is subject to selection biases, either through self-selection by the users or through the actions of the recommendation system itself. In this paper, we provide a principled approach…

机器学习 · 计算机科学 2016-05-30 Tobias Schnabel , Adith Swaminathan , Ashudeep Singh , Navin Chandak , Thorsten Joachims

Several studies indicate that deep learning models can learn to detect breast cancer from mammograms (X-ray images of the breasts). However, challenges with overfitting and poor generalisability prevent their routine use in the clinic.…

图像与视频处理 · 电气工程与系统科学 2025-02-05 Emir Ahmed , Spencer A. Thomas , Ciaran Bench

Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

As the use of machine learning (ML) models in product development and data-driven decision-making processes became pervasive in many domains, people's focus on building a well-performing model has increasingly shifted to understanding how…

人机交互 · 计算机科学 2020-06-02 Sungsoo Ray Hong , Jessica Hullman , Enrico Bertini

Interpretability has become an essential topic for artificial intelligence in some high-risk domains such as healthcare, bank and security. For commonly-used tabular data, traditional methods trained end-to-end machine learning models with…

人工智能 · 计算机科学 2022-08-18 Haixiao Chi , Dawei Wang , Gaojie Cui , Feng Mao , Beishui Liao

Optimizing credit limits, interest rates, and loan terms is crucial for managing borrower risk and lifetime value (LTV) in personal loan platform. However, counterfactual estimation of these continuous, multi-dimensional treatments faces…

机器学习 · 计算机科学 2025-08-12 Kexin Zhao , Bo Wang , Cuiying Zhao , Tongyao Wan

Data is crucial for machine learning (ML) applications, yet acquiring large datasets can be costly and time-consuming, especially in complex, resource-intensive fields like biopharmaceuticals. A key process in this industry is upstream…

机器学习 · 计算机科学 2025-06-23 Johnny Peng , Thanh Tung Khuat , Katarzyna Musial , Bogdan Gabrys

Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data. However, these models suffer from scaling issues: they have to learn pairwise interactions between each piece of information in…

The drug discovery stage is a vital aspect of the drug development process and forms part of the initial stages of the development pipeline. In recent times, machine learning-based methods are actively being used to model drug-target…

机器学习 · 计算机科学 2020-09-02 Brighter Agyemang , Wei-Ping Wu , Michael Yelpengne Kpiebaareh , Zhihua Lei , Ebenezer Nanor , Lei Chen

Traditional models grounded in first principles often struggle with accuracy as the system's complexity increases. Conversely, machine learning approaches, while powerful, face challenges in interpretability and in handling physical…

机器学习 · 计算机科学 2024-01-31 Jessica Leoni , Valentina Breschi , Simone Formentin , Mara Tanelli

Deep neural networks have been well-known for their superb handling of various machine learning and artificial intelligence tasks. However, due to their over-parameterized black-box nature, it is often difficult to understand the prediction…

机器学习 · 计算机科学 2022-07-18 Xuhong Li , Haoyi Xiong , Xingjian Li , Xuanyu Wu , Xiao Zhang , Ji Liu , Jiang Bian , Dejing Dou

In the future, competitive advantages will be given to organisations that can extract valuable information from massive data and make better decisions. In most cases, this data comes from multiple sources. Therefore, the challenge is to…

应用统计 · 统计学 2016-05-11 Igor Barahona , Judith Cavazos , Jian-Bo Yang

Multi-agent robotic systems are increasingly operating in real-world environments in close proximity to humans, yet are largely controlled by policy models with inscrutable deep neural network representations. We introduce a method for…

机器学习 · 计算机科学 2023-02-24 Renos Zabounidis , Joseph Campbell , Simon Stepputtis , Dana Hughes , Katia Sycara
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