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Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements.…

This paper focuses on the task of survival time analysis for lung cancer. Although much progress has been made in this problem in recent years, the performance of existing methods is still far from satisfactory. Traditional and some deep…

计算机视觉与模式识别 · 计算机科学 2022-11-08 Yujiao Wu , Yaxiong Wang , Xiaoshui Huang , Fan Yang , Sai Ho Ling , Steven Weidong Su

Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…

计算机视觉与模式识别 · 计算机科学 2026-04-10 Mustafa Yurdakul , Şakir Taşdemir

Neuroblastoma is a strongly heterogeneous cancer with very diverse clinical courses that may vary from spontaneous regression to fatal progression; an accurate patient's risk estimation at diagnosis is essential to design appropriate tumor…

定量方法 · 定量生物学 2018-02-23 Valerio Maggio , Marco Chierici , Giuseppe Jurman , Cesare Furlanello

Risk stratification is a key tool in clinical decision-making, yet current approaches often fail to translate sophisticated survival analysis into actionable clinical criteria. We present a novel method for unsupervised machine learning…

Recent radiomic studies have witnessed promising performance of deep learning techniques in learning radiomic features and fusing multimodal imaging data. Most existing deep learning based radiomic studies build predictive models in a…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Pamela Boimel , James Janopaul-Naylor , Haoyu Zhong , Ying Xiao , Edgar Ben-Josef , Yong Fan

Survival risk stratification is an important step in clinical decision making for breast cancer management. We propose a novel deep learning approach for this purpose by integrating histopathological imaging, genetic and clinical data. It…

计算机视觉与模式识别 · 计算机科学 2024-02-20 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Cancer histology reveals disease progression and associated molecular processes, and contains rich phenotypic information that is predictive of outcome. In this paper, we developed a computational approach based on deep learning to predict…

图像与视频处理 · 电气工程与系统科学 2019-09-20 Saima Rathore , Muhammad Aksam Iftikhar , Zissimos Mourelatos

Cancer survival prediction requires integrating pathological Whole Slide Images (WSIs) and genomic profiles, a challenging task due to the inherent heterogeneity and the complexity of modeling both inter- and intra-modality interactions.…

图像与视频处理 · 电气工程与系统科学 2025-07-08 Mingxin Liu , Chengfei Cai , Jun Li , Pengbo Xu , Jinze Li , Jiquan Ma , Jun Xu

Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Hasaan Maqsood , Saif Ur Rehman Khan

We explore how Deep Learning (DL) can be utilized to predict prognosis of acute myeloid leukemia (AML). Out of TCGA (The Cancer Genome Atlas) database, 94 AML cases are used in this study. Input data include age, 10 common cytogenetic and…

机器学习 · 计算机科学 2018-11-01 Mei Lin , Vanya Jaitly , Iris Wang , Zhihong Hu , Lei Chen , Md. Amer Wahed , Zeyad Kanaan , Adan Rios , Andy N. D. Nguyen

Survival prediction is a major concern for cancer management. Deep survival models based on deep learning have been widely adopted to perform end-to-end survival prediction from medical images. Recent deep survival models achieved promising…

图像与视频处理 · 电气工程与系统科学 2024-10-17 Mingyuan Meng , Bingxin Gu , Michael Fulham , Shaoli Song , Dagan Feng , Lei Bi , Jinman Kim

Cancer claims millions of lives yearly worldwide. While many therapies have been made available in recent years, by in large cancer remains unsolved. Exploiting computational predictive models to study and treat cancer holds great promise…

This paper explores machine learning (ML) models for classifying lung cancer levels to improve diagnostic accuracy and prognosis. Through parameter tuning and rigorous evaluation, we assess various ML algorithms. Techniques like minimum…

人工智能 · 计算机科学 2024-12-05 Mohsen Asghari Ilani , Saba Moftakhar Tehran , Ashkan Kavei , Hamed Alizadegan

Improving patient outcomes depends on the prompt and accurate diagnosis of brain tumors, but manual MRI scan analysis is still time-consuming and unreliable. Although deep learning has shown promise, many of the models that are now in use…

图像与视频处理 · 电气工程与系统科学 2026-05-14 Md Fahimul Kabir Chowdhury , Jannatul Ferdous

Deep neural networks for survival prediction outper-form classical approaches in discrimination, which is the ordering of patients according to their time-of-event. Conversely, classical approaches like the Cox Proportional Hazards model…

机器学习 · 计算机科学 2022-09-01 Patrick Fuhlert , Anne Ernst , Esther Dietrich , Fabian Westhaeusser , Karin Kloiber , Stefan Bonn

Lung and colon cancers are predominant contributors to cancer mortality. Early and accurate diagnosis is crucial for effective treatment. By utilizing imaging technology in different image detection, learning models have shown promise in…

图像与视频处理 · 电气工程与系统科学 2025-01-28 Diponkor Bala , S M Rakib Ul Karim , Rownak Ara Rasul

Cancer remains a leading global health challenge and a major cause of mortality. This study leverages machine learning (ML) to predict the survivability of cancer patients with metastatic patterns using the comprehensive MSK-MET dataset,…

定量方法 · 定量生物学 2025-04-10 Polycarp Nalela , Deepthi Rao , Praveen Rao

Probabilistic survival predictions from models trained with Maximum Likelihood Estimation (MLE) can have high, and sometimes unacceptably high variance. The field of meteorology, where the paradigm of maximizing sharpness subject to…

机器学习 · 计算机科学 2019-06-20 Anand Avati , Tony Duan , Sharon Zhou , Kenneth Jung , Nigam H. Shah , Andrew Ng

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

图像与视频处理 · 电气工程与系统科学 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie