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Multi-Objective Reinforcement Learning (MORL) presents significant challenges and opportunities for optimizing multiple objectives in Large Language Models (LLMs). We introduce a MORL taxonomy and examine the advantages and limitations of…

计算与语言 · 计算机科学 2025-09-29 Lingxiao Kong , Cong Yang , Oya Deniz Beyan , Zeyd Boukhers

The accurate classification of benign and malignant pulmonary nodules in CT scans is critical for early lung cancer screening, yet remains challenging due to the multi-scale and heterogeneous nature of pulmonary nodules. While deep learning…

计算机视觉与模式识别 · 计算机科学 2026-05-14 Jinyue Li , Yuzhou Yu , Jingjing Yang , Meng Fu , Yani Zhang , Shuyao He , Dianlong Ge , Xin Ning , Yannan Chu , Qiankun Li

Standard (network) meta-analysis methods for medical test accuracy evaluation analyse the data separately for each test threshold - wasting data - unless every study reports all thresholds. Previously proposed "multiple threshold" models…

Lung tumors, especially those located close to or surrounded by soft tissues like the mediastinum, are difficult to segment due to the low soft tissue contrast on computed tomography images. Magnetic resonance images contain superior…

图像与视频处理 · 电气工程与系统科学 2019-09-11 Jue Jiang , Jason Hu , Neelam Tyagi , Andreas Rimner , Sean L. Berry , Joseph O. Deasy , Harini Veeraraghavan

Sample efficiency and exploration remain critical challenges in Deep Reinforcement Learning (DRL), particularly in complex domains. Offline RL, which enables agents to learn optimal policies from static, pre-collected datasets, has emerged…

机器学习 · 计算机科学 2025-12-23 Gaurav Chaudhary , Wassim Uddin Mondal , Laxmidhar Behera

This paper presents and validates a novel lung nodule classification algorithm that uses multifractal features found in X-ray images. The proposed method includes a pre-processing step where two enhancement techniques are applied: histogram…

计算机视觉与模式识别 · 计算机科学 2022-07-04 Isabella María Sierra-Ponce , Angela Mireya León-Mecías , Damian Valdés-Santiago

Objective: Molecular testing (MT) classifies cytologically indeterminate thyroid nodules as benign or malignant with high sensitivity but low positive predictive value (PPV), only using molecular profiles, ignoring ultrasound (US) imaging…

Detection and classification of pulmonary nodules is a challenge in medical image analysis due to the variety of shapes and sizes of nodules and their high concealment. Despite the success of traditional deep learning methods in image…

图像与视频处理 · 电气工程与系统科学 2025-02-28 Junji Lin , Yi Zhang , Yunyue Pan , Yuli Chen , Chengchang Pan , Honggang Qi

Detection of pulmonary nodules in chest CT imaging plays a crucial role in early diagnosis of lung cancer. Manual examination is highly time-consuming and error prone, calling for computer-aided detection, both to improve efficiency and…

计算机视觉与模式识别 · 计算机科学 2018-07-17 Zhongliu Xie

In this paper, we propose a novel framework with 3D convolutional networks (ConvNets) for automated detection of pulmonary nodules from low-dose CT scans, which is a challenging yet crucial task for lung cancer early diagnosis and…

计算机视觉与模式识别 · 计算机科学 2017-08-15 Qi Dou , Hao Chen , Yueming Jin , Huangjing Lin , Jing Qin , Pheng-Ann Heng

In real-world decision optimization, often multiple competing objectives must be taken into account. Following classical reinforcement learning, these objectives have to be combined into a single reward function. In contrast,…

机器学习 · 计算机科学 2022-04-12 Johannes Dornheim

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

计算机视觉与模式识别 · 计算机科学 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

计算机视觉与模式识别 · 计算机科学 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Mean Deviation (MD) is a critical metric for assessing visual field loss in ophthalmology. While previous work has focused solely on predicting MD from Optical Coherence Tomography (OCT), it is intuitive to assume that combining OCT with…

计算机视觉与模式识别 · 计算机科学 2026-05-27 Haojie Yin , Chengcheng Feng , Tianyi Liu , Tianqi Zhang , Kaizhu Huang

Ordinal regression is an important type of learning, which has properties of both classification and regression. Here we describe a simple and effective approach to adapt a traditional neural network to learn ordinal categories. Our…

机器学习 · 计算机科学 2007-05-23 Jianlin Cheng

In this work, we present a fully automated lung computed tomography (CT) cancer diagnosis system, DeepLung. DeepLung consists of two components, nodule detection (identifying the locations of candidate nodules) and classification…

计算机视觉与模式识别 · 计算机科学 2018-01-30 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie

Deep Neural Networks are known to be brittle to even minor distribution shifts compared to the training distribution. While one line of work has demonstrated that Simplicity Bias (SB) of DNNs - bias towards learning only the simplest…

机器学习 · 计算机科学 2022-10-05 Sravanti Addepalli , Anshul Nasery , R. Venkatesh Babu , Praneeth Netrapalli , Prateek Jain

We consider the problem of distributionally robust multimodal machine learning. Existing approaches often rely on merging modalities on the feature level (early fusion) or heuristic uncertainty modeling, which downplays modality-aware…

机器学习 · 计算机科学 2025-11-11 Peilin Yang , Yu Ma

Estimating a causal effect from observational data can be biased if we do not control for self-selection. This selection is based on confounding variables that affect the treatment assignment and the outcome. Propensity score methods aim to…

计量经济学 · 经济学 2021-09-10 Daniel Jacob

In recent years, dynamically growing data and incrementally growing number of classes pose new challenges to large-scale data classification research. Most traditional methods struggle to balance the precision and computational burden when…

机器学习 · 计算机科学 2016-11-01 Tingting Xie , Yuxing Peng , Changjian Wang