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Current research in clone detection suffers from poor ecosystems for evaluating precision of clone detection tools. Corpora of labeled clones are scarce and incomplete, making evaluation labor intensive and idiosyncratic, and limiting inter…

Background: Phage therapy shows promise for treating antibiotic-resistant Klebsiella infections. Identifying phage depolymerases that target Klebsiella capsular polysaccharides is crucial, as these capsules contribute to biofilm formation…

基因组学 · 定量生物学 2025-01-29 George Wright , Slawomir Michniewski , Eleanor Jameson , Fayyaz ul Amir Afsar Minhas

The recent monkeypox outbreak has raised significant public health concerns due to its rapid spread across multiple countries. Monkeypox can be difficult to distinguish from chickenpox and measles in the early stages because the symptoms of…

图像与视频处理 · 电气工程与系统科学 2024-08-14 Niloy Kumar Kundu , Mainul Karim , Sarah Kobir , Dewan Md. Farid

The adaptive immune system of vertebrates can detect, respond to, and memorize diverse pathogens from past experience. While the clonal selection of T helper (Th) cells is the simple and established mechanism to better recognize new…

种群与进化 · 定量生物学 2021-03-17 Takuya Kato , Tetsuya J. Kobayashi

Machine and deep learning have grown in popularity and use in biological research over the last decade but still present challenges in interpretability of the fitted model. The development and use of metrics to determine features driving…

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

机器学习 · 计算机科学 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

Code cloning negatively affects industrial software and threatens intellectual property. This paper presents a novel approach to detecting cloned software by using a bijective matching technique. The proposed approach focuses on increasing…

软件工程 · 计算机科学 2014-08-14 Hosam AlHakami , Feng Chen , Helge Janicke

Binary code similarity detection is a core task in reverse engineering. It supports malware analysis and vulnerability discovery by identifying semantically similar code in different contexts. Modern methods have progressed from manually…

人工智能 · 计算机科学 2025-09-30 Charles E. Gagnon , Steven H. H. Ding , Philippe Charland , Benjamin C. M. Fung

Subspace clustering has been extensively studied from the hypothesis-and-test, algebraic, and spectral clustering based perspectives. Most assume that only a single type/class of subspace is present. Generalizations to multiple types are…

计算机视觉与模式识别 · 计算机科学 2019-04-04 Xun Xu , Loong-Fah Cheong , Zhuwen Li

In the context of post-hoc interpretability, this paper addresses the task of explaining the prediction of a classifier, considering the case where no information is available, neither on the classifier itself, nor on the processed data…

This work presents twelve fine-tuned deep learning architectures to solve the bacterial classification problem over the Digital Image of Bacterial Species Dataset. The base architectures were mainly published as mobile or efficient…

计算机视觉与模式识别 · 计算机科学 2021-06-14 R. Gallardo García , S. Jarquín Rodríguez , B. Beltrán Martínez , C. Hernández Gracidas , R. Martínez Torres

Automated bacterial colony counting from images is an important technique to obtain data required for the development of vaccines and antibiotics. However, bacterial colonies present unique machine vision challenges that affect counting,…

计算机视觉与模式识别 · 计算机科学 2026-04-23 Minghua Zheng , Na Helian , Peter C. R. Lane , Yi Sun , Allen Donald

To address the issues of limited samples, time-consuming feature design, and low accuracy in detection and classification of breast cancer pathological images, a breast cancer image classification model algorithm combining deep learning and…

图像与视频处理 · 电气工程与系统科学 2024-09-12 Weimin Wang , Yufeng Li , Xu Yan , Mingxuan Xiao , Min Gao

Automated white blood cell (WBC) classification is essential for leukemia screening but remains challenged by extreme class imbalance, long-tail distributions, and domain shift, leading deep models to overfit dominant classes and fail on…

计算机视觉与模式识别 · 计算机科学 2026-03-31 Duc T. Nguyen , Hoang-Long Nguyen , Huy-Hieu Pham

In this paper, we introduce a novel and interpretable methodology to cluster subjects suffering from cancer, based on features extracted from their biopsies. Contrary to existing approaches, we propose here to capture complex patterns in…

定量方法 · 定量生物学 2020-07-07 Yassine El Ouahidi , Matis Feller , Matthieu Talagas , Bastien Pasdeloup

The antinuclear antibody detection with human epithelial cells is a popular approach for autoimmune diseases diagnosis. The manual evaluation demands time, effort and capital, and automation in screening can greatly aid the physicians in…

计算机视觉与模式识别 · 计算机科学 2018-10-31 Vibha Gupta , Arnav Bhavsar

Increasingly complex generative models are being used across disciplines as they allow for realistic characterization of data, but a common difficulty with them is the prohibitively large computational cost to evaluate the likelihood…

统计计算 · 统计学 2017-03-06 Michael U. Gutmann , Ritabrata Dutta , Samuel Kaski , Jukka Corander

Recurrent neural networks with differentiable attention mechanisms have had success in generative and classification tasks. We show that the classification performance of such models can be enhanced by guiding a randomly initialized model…

机器学习 · 计算机科学 2017-12-18 Jack Lindsey

Genome wide comparisons between enteric bacteria yield large sets of conserved putative regulatory sites on a gene by gene basis that need to be clustered into regulons. Using the assumption that regulatory sites can be represented as…

生物物理 · 物理学 2009-11-07 Erik van Nimwegen , Mihaela Zavolan , Nikolaus Rajewsky , Eric D. Siggia

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

分布式、并行与集群计算 · 计算机科学 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick
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