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Alzheimer's disease (AD) is the most common cause of dementia. An early detection is crucial for slowing down the disease and mitigating risks related to the progression. While the combination of MRI and FDG-PET is the best image-based tool…

图像与视频处理 · 电气工程与系统科学 2022-06-17 Marcel Kollovieh , Matthias Keicher , Stephan Wunderlich , Hendrik Burwinkel , Thomas Wendler , Nassir Navab

The ability to accurately detect onset of dementia is important in the treatment of the disease. Clinically, the diagnosis of Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI) patients are based on an integrated assessment of…

信号处理 · 电气工程与系统科学 2022-11-18 Wan-Ting Hsieh , Jeremy Lefort-Besnard , Hao-Chun Yang , Li-Wei Kuo , Chi-Chun Lee

Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

机器学习 · 计算机科学 2022-12-12 Harshit Parmar , Eric Walden

As the global burden of Alzheimer's disease (AD) continues to grow, early and accurate detection has become increasingly critical, especially in regions with limited access to advanced diagnostic tools. We propose BRAINS (Biomedical…

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

MEG are non invasive neuroimaging techniques with excellent temporal and spatial resolution, crucial for studying brain function in dementia and Alzheimer Disease. They identify changes in brain activity at various Alzheimer stages,…

Alzheimer's disease (AD) and mild cognitive impairment (MCI), continue to be widely studied. While there is no consensus on whether MCIs actually "convert" to AD, the more important question is not whether MCIs convert, but what is the best…

神经元与认知 · 定量生物学 2015-05-28 Yaman Aksu , David J. Miller , George Kesidis , Don C. Bigler , Qing X. Yang

The present study performs a comprehensive fairness analysis of machine learning (ML) models for the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) from MRI-derived neuroimaging features. Biases associated with…

机器学习 · 计算机科学 2025-05-30 Maria Eleftheria Vlontzou , Maria Athanasiou , Christos Davatzikos , Konstantina S. Nikita

The identification of Alzheimer's disease (AD) and its early stages using structural magnetic resonance imaging (MRI) has been attracting the attention of researchers. Various data-driven approaches have been introduced to capture subtle…

人工智能 · 计算机科学 2021-08-11 Changhyun Park , Heung-Il Suk

Introduction: Alzheimer's disease is a type of dementia in which early diagnosis plays a major rule in the quality of treatment. Among new works in the diagnosis of Alzheimer's disease, there are many of them analyzing the voice stream…

机器学习 · 计算机科学 2019-10-02 S. Soroush Haj Zargarbashi , Bagher Babaali

The diagnosis of early stages of Alzheimer's disease (AD) is essential for timely treatment to slow further deterioration. Visualizing the morphological features for the early stages of AD is of great clinical value. In this work, a novel…

图像与视频处理 · 电气工程与系统科学 2021-11-29 Wen Yu , Baiying Lei , Yanyan Shen , Shuqiang Wang , Yong Liu , Zhiguang Feng , Yong Hu , Michael K. Ng

Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…

机器学习 · 计算机科学 2025-04-03 Jing Wang , Jun-En Ding , Feng Liu , Elisa Kallioniemi , Shuqiang Wang , Wen-Xiang Tsai , Albert C. Yang

Alzheimer's disease (AD), a degenerative brain condition, can benefit from early prediction to slow its progression. As the disease progresses, patients typically undergo brain atrophy. Current prediction methods for Alzheimers disease…

计算机视觉与模式识别 · 计算机科学 2025-11-27 Xin Honga , Jie Lin , Minghui Wang

Alzheimer's disease has an increasing prevalence in the population world-wide, yet current diagnostic methods based on recommended biomarkers are only available in specialized clinics. Due to these circumstances, Alzheimer's disease is…

Mild cognitive impairment (MCI) is the prodromal stage of Alzheimer's disease (AD) and thus enrolling MCI subjects to undergo clinical trials is worthwhile. However, MCI groups usually show significant diversity and heterogeneity in the…

定量方法 · 定量生物学 2025-08-26 Muheng Shang , Jin Zhang , Junwei Han , Lei Du

Unsupervised learning can discover various unseen diseases, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a single medical image to detect outliers either in the…

图像与视频处理 · 电气工程与系统科学 2020-03-18 Changhee Han , Leonardo Rundo , Kohei Murao , Zoltán Ádám Milacski , Kazuki Umemoto , Evis Sala , Hideki Nakayama , Shin'ichi Satoh

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

机器学习 · 计算机科学 2016-11-15 Ehsan Hosseini-Asl , Robert Keynto , Ayman El-Baz

Alzheimer's Disease is a global health challenge that requires early and accurate detection to improve patient outcomes. Magnetic Resonance Imaging (MRI) holds significant diagnostic potential, but its effective analysis remains a…

密码学与安全 · 计算机科学 2023-11-02 Stefan Kambiz Behfar , Qumars Behfar , Marzie Hosseinpour

Alzheimer's disease (AD) is a prevalent and debilitating neurodegenerative disorder impacting a large aging population. Detecting AD in all its presymptomatic and symptomatic stages is crucial for early intervention and treatment. An active…

计算机视觉与模式识别 · 计算机科学 2023-10-31 Yasmine Mustafa , Tie Luo

Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

计算与语言 · 计算机科学 2020-11-21 Mireia Farrús , Joan Codina-Filbà