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We present a non-invasive, label-free method of imaging blood cells flowing through human capillaries in vivo using oblique back-illumination capillaroscopy (OBC). Green light illumination allows simultaneous phase and absorption contrast,…

生物物理 · 物理学 2020-01-20 Gregory N. McKay , Nela Mohan , Nicholas J. Durr

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

The accurate tracking of live cells using video microscopy recordings remains a challenging task for popular state-of-the-art image processing based object tracking methods. In recent years, several existing and new applications have…

图像与视频处理 · 电气工程与系统科学 2025-02-03 Gergely Szabó , Paolo Bonaiuti , Andrea Ciliberto , András Horváth

Deep neural networks are rapidly emerging as data analysis tools, often outperforming the conventional techniques used in complex microfluidic systems. One fundamental analysis frequently desired in microfluidic experiments is counting and…

计算机视觉与模式识别 · 计算机科学 2022-08-17 Mihir Durve , Adriano Tiribocchi , Fabio Bonaccorso , Andrea Montessori , Marco Lauricella , Michal Bogdan , Jan Guzowski , Sauro Succi

Video microscopy has a long history of providing insights and breakthroughs for a broad range of disciplines, from physics to biology. Image analysis to extract quantitative information from video microscopy data has traditionally relied on…

图像与视频处理 · 电气工程与系统科学 2024-06-12 Benjamin Midtvedt , Saga Helgadottir , Aykut Argun , Jesús Pineda , Daniel Midtvedt , Giovanni Volpe

Automatic cell tracking in dense environments is plagued by inaccurate correspondences and misidentification of parent-offspring relationships. In this paper, we introduce a novel cell tracking algorithm named DenseTrack, which integrates…

图像与视频处理 · 电气工程与系统科学 2024-07-08 Tanjin Taher Toma , Yibo Wang , Andreas Gahlmann , Scott T. Acton

Automated in-vitro cell detection and counting have been a key theme for artificial and intelligent biological analysis such as biopsy, drug analysis and decease diagnosis. Along with the rapid development of microfluidics and lab-on-chip…

计算机视觉与模式识别 · 计算机科学 2020-01-08 Tiancheng Xia , Richard Jiang , YongQing Fu , Nanlin Jin

Single particle tracking is essential in many branches of science and technology, from the measurement of biomolecular forces to the study of colloidal crystals. Standard current methods rely on algorithmic approaches: by fine-tuning…

软凝聚态物质 · 物理学 2018-12-07 Saga Helgadottir , Aykut Argun , Giovanni Volpe

Accurate tool tracking is essential for the success of computer-assisted intervention. Previous efforts often modeled tool trajectories rigidly, overlooking the dynamic nature of surgical procedures, especially tracking scenarios like…

计算机视觉与模式识别 · 计算机科学 2024-12-30 Chinedu Innocent Nwoye , Nicolas Padoy

Ultrasound technology enables safe, non-invasive imaging of dynamic tissue behavior, making it a valuable tool in medicine, biomechanics, and sports science. However, accurately tracking tissue motion in B-mode ultrasound remains…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Praneeth Namburi , Roger Pallarès-López , Jessica Rosendorf , Duarte Folgado , Brian W. Anthony

A systematic analysis of the cell behavior requires automated approaches for cell segmentation and tracking. While deep learning has been successfully applied for the task of cell segmentation, there are few approaches for simultaneous cell…

计算机视觉与模式识别 · 计算机科学 2024-10-28 Katharina Löffler , Ralf Mikut

Analyzing the dynamic changes of cellular morphology is important for understanding the various functions and characteristics of live cells, including stem cells and metastatic cancer cells. To this end, we need to track all points on the…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Junbong Jang , Kwonmoo Lee , Tae-Kyun Kim

Cell segmentation and tracking in microscopy images are of great significance to new discoveries in biology and medicine. In this study, we propose a novel approach to combine cell segmentation and cell tracking into a unified end-to-end…

计算机视觉与模式识别 · 计算机科学 2021-02-23 Yuqian Chen , Yang Song , Chaoyi Zhang , Fan Zhang , Lauren O'Donnell , Wojciech Chrzanowski , Weidong Cai

Automated analysis of volumetric medical imaging on edge devices is severely constrained by the high memory and computational demands of 3D Convolutional Neural Networks (CNNs). This paper develops a lightweight computer vision framework…

计算机视觉与模式识别 · 计算机科学 2026-01-07 Amirreza Parvahan , Mohammad Hoseyni , Javad Khoramdel , Amirhossein Nikoofard

Tracking microrobots is challenging, considering their minute size and high speed. As the field progresses towards developing microrobots for biomedical applications and conducting mechanistic studies in physiologically relevant media…

计算机视觉与模式识别 · 计算机科学 2023-10-17 Medha Sawhney , Bhas Karmarkar , Eric J. Leaman , Arka Daw , Anuj Karpatne , Bahareh Behkam

Deep learning has achieved spectacular performance in image and speech recognition and synthesis. It outperforms other machine learning algorithms in problems where large amounts of data are available. In the area of measurement technology,…

定量方法 · 定量生物学 2019-08-20 Yueqin Li , Ata Mahjoubfar , Claire Lifan Chen , Kayvan Reza Niazi , Li Pei , Bahram Jalali

Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments…

计算机视觉与模式识别 · 计算机科学 2022-08-08 Elena Alexander , Kam W. Leong , Andrew F. Laine

Circulating tumor cells (CTCs) are cancer cells found in the bloodstream that serve as biomarkers for early cancer detection, prognostication, and disease monitoring. However, CTC detection remains challenging due to low cell abundance and…

Accurate classification of blood cells plays a key role in improving automated blood analysis for both medical and veterinary applications. This work presents a two-stage deep clustering method for classifying blood cells from…

定量方法 · 定量生物学 2025-09-25 Mihaela Macarie-Ancau , Adrian Groza

Modern smart vision sensors need on-device intelligence to process video streams, as cloud computing is often impractical due to bandwidth, latency, and privacy constraints. However, these sensory systems typically rely on ultra-low-power…

计算机视觉与模式识别 · 计算机科学 2026-05-18 Luca Bompani , Manuele Rusci , Luca Benini , Daniele Palossi , Francesco Conti
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