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A broad range of scientific and industrial disciplines require precise optical measurements at very low light levels. Single-photon detectors combining high efficiency and high time resolution are pivotal in such experiments. By using…

This paper introduces a novel low-cost device prototype for the automatic diagnosis of diseases, utilizing inputted symptoms and personal background. The engineering goal is to solve the problem of limited healthcare access with a single…

计算机与社会 · 计算机科学 2019-01-07 Neil Deshmukh

There is an urgent need for the development of novel and truly rapid (equal or less than 1 hour) antibiotic susceptibility testing (AST) platforms in order to provide best antimicrobial prescribing practices and to help reduce the…

亚细胞过程 · 定量生物学 2025-01-22 Allen Fraiman , Lawrence Ziegler

The integration of compressive sensing with real-time embedded systems opens new possibilities for efficient, low-power biomedical signal acquisition. This paper presents a custom hardware platform based on the RP2350 micro-controller,…

系统与控制 · 电气工程与系统科学 2025-07-11 Rens Baeyens , Dennis Laurijssen , Jan Steckel , Walter Daems

Mobile medical imaging devices are invaluable for clinical diagnostic purposes both in and outside healthcare institutions. Among the various imaging modalities, only a few are readily portable. Magnetic resonance imaging (MRI), the gold…

The recent evolution of software and hardware technologies is leading to a renewed computational interest in Particle-In-Cell (PIC) methods such as the Material Point Method (MPM). Indeed, provided some critical aspects are properly…

计算物理 · 物理学 2024-12-11 Paolo Joseph Baioni , Tommaso Benacchio , Luigi Capone , Carlo de Falco

Antimicrobial biomaterials are critical to aid in the regeneration of oral soft tissue and prevent or treat localised bacterial infections. With the rising trend in antibiotic resistance, there is a pressing clinical need for new…

组织与器官 · 定量生物学 2021-01-06 Amy Contreras , Michael J. Raxworthy , Simon Wood , Jessica D. Schiffman , Giuseppe Tronci

Scanning Probe Microscopy (SPM) is the primary tool for exploring nanoscale functionality, yet standard single-frequency operation is fundamentally limited, because the dynamic tip-sample interaction is mathematically underdetermined. While…

We demonstrate the capabilities of a highly parallel, active pixel detector for large-area, mass spectrometric imaging of biological tissue sections. A bare Timepix assembly (512x512 pixels) is combined with chevron microchannel plates on…

仪器与探测器 · 物理学 2013-05-24 Julia H. Jungmann , Donald F. Smith , Luke MacAleese , Ivo Klinkert , Jan Visser , Ron M. A. Heeren

The investigation of paramagnetic species (such as point defects, dopants, and impurities) in solid-state electronic devices is significant because of their effect on device performance. Conventionally, these species are detected and imaged…

材料科学 · 物理学 2015-05-20 Itai Katz , Matthias Fehr , Alexander Schnegg , Klaus Lips , Aharon Blank

A flow-through sensing platform based on open-ended porous silicon (PSi) microcavity membranes that are compatible with integration in on-chip sensor arrays is demonstrated. Due to the high aspect ratio of PSi nanopores, the performance of…

材料科学 · 物理学 2016-10-27 Yiliang Zhao , Girija Gaur , Scott T. Retterer , Paul E. Laibinis , Sharon M. Weiss

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

医学物理 · 物理学 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

Spatial separation of suspended particles based on contrast in their physical or chemical properties forms the basis of various biological assays performed on lab-on-achip devices. To electronically acquire this information, we have…

新兴技术 · 计算机科学 2018-08-13 Ningquan Wang , Ruxiu Liu , Roozbeh Khodambashi , Norh Asmare , A. Fatih Sarioglu

Microplastics (MPs) are ubiquitous in all ecosystems, affecting wildlife and, ultimately, human health. The complexity of natural samples plus the unspecificity of their treatments to isolate polymers renders the characterization of…

仪器与探测器 · 物理学 2025-04-01 Adrian Lopez-Rosales , Jose Andrade , Borja Ferreiro , Soledad Muniategui

Nuclear magnetic resonance spectroscopy (MRS) allows for the determination of atomic structures and concentrations of different chemicals in a biochemical sample of interest. MRS is used in vivo clinically to aid in the diagnosis of several…

医学物理 · 物理学 2021-05-04 Zohaib Iqbal , Dan Nguyen , M. Albert Thomas , Steve Jiang

The use of conventional imaging techniques becomes problematic when faced with challenging logistics and confined environments. In particular, such scenarios are not unusual in the field of archaeological and mining explorations as well as…

仪器与探测器 · 物理学 2022-02-03 S. Basnet , E. Cortina Gil , P. Demin , R. M. I. D. Gamage , A. Giammanco , R. Karnam , M. Moussawi , A. Samalan , M. Tytgat

An experimental protocol is developed to directly measure the new material functions revealed by medium amplitude parallel superposition (MAPS) rheology. This experimental protocol measures the medium amplitude response of a material to a…

软凝聚态物质 · 物理学 2022-02-10 Kyle R. Lennon , Michela Geri , Gareth H. McKinley , James W. Swan

Virtually all clinical applications of magnetic nanoparticles (MNPs) require the formulation of biocompatible, water-based magnetic colloids. For magnetic hyperthermia, the requirements also include a high colloidal stability against…

化学物理 · 物理学 2016-09-19 B. Sanz , M. P. Calatayud , N. Cassinelli , M. R. Ibarra , G. F. Goya

Micromagnetic beads are widely used in biomedical applications for cell separation, drug delivery, and hypothermia cancer treatment. Here we propose to use self-organized magnetic bead structures which accumulate on fixed magnetic seeding…

Magnetic Resonance Fingerprinting (MRF) is a time-efficient approach to quantitative MRI for multiparametric tissue mapping. The reconstruction of quantitative maps requires tailored algorithms for removing aliasing artefacts from the…

图像与视频处理 · 电气工程与系统科学 2024-12-19 Perla Mayo , Matteo Cencini , Carolin M. Pirkl , Marion I. Menzel , Michela Tosetti , Bjoern H. Menze , Mohammad Golbabaee