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相关论文: Interpretable Survival Prediction for Colorectal C…

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Colorectal liver metastases (CLM) significantly impact colon cancer patients, influencing survival based on systemic chemotherapy response. Traditional methods like tumor grading scores (e.g., tumor regression grade - TRG) for prognosis…

The rapidly emerging field of deep learning-based computational pathology has demonstrated promise in developing objective prognostic models from histology whole slide images. However, most prognostic models are either based on histology or…

Background: Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide. Accurate survival prediction is essential for treatment stratification, yet existing pathology foundation models often overlook…

计算机视觉与模式识别 · 计算机科学 2026-04-15 Hikmat Khan , Usama Sajjad , Metin N. Gurcan , Anil Parwani , Wendy L. Frankel , Wei Chen , Muhammad Khalid Khan Niazi

The evaluation of the Human Epidermal growth factor Receptor-2 (HER2) expression is an important prognostic biomarker for breast cancer treatment selection. However, HER2 scoring has notoriously high interobserver variability due to stain…

图像与视频处理 · 电气工程与系统科学 2022-11-18 Manh Dan Pham , Cyprien Tilmant , Stéphanie Petit , Isabelle Salmon , Saima Ben Hadj , Rutger H. J. Fick

Survival analysis is widely used as a technique to model time-to-event data when some data is censored, particularly in healthcare for predicting future patient risk. In such settings, survival models must be both accurate and interpretable…

机器学习 · 计算机科学 2024-04-24 Mike Van Ness , Madeleine Udell

Survival prediction is a major concern for cancer management. Deep survival models based on deep learning have been widely adopted to perform end-to-end survival prediction from medical images. Recent deep survival models achieved promising…

图像与视频处理 · 电气工程与系统科学 2024-10-17 Mingyuan Meng , Bingxin Gu , Michael Fulham , Shaoli Song , Dagan Feng , Lei Bi , Jinman Kim

Variational Level Set (VLS) has been a widely used method in medical segmentation. However, segmentation accuracy in the VLS method dramatically decreases when dealing with intervening factors such as lighting, shadows, colors, etc.…

计算机视觉与模式识别 · 计算机科学 2018-10-12 T. Hoang Ngan Le , Raajitha Gummadi , Marios Savvides

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

计算机视觉与模式识别 · 计算机科学 2022-10-11 Sean Grullon , Vaughn Spurrier , Jiayi Zhao , Corey Chivers , Yang Jiang , Kiran Motaparthi , Michael Bonham , Julianna Ianni

When oncologists estimate cancer patient survival, they rely on multimodal data. Even though some multimodal deep learning methods have been proposed in the literature, the majority rely on having two or more independent networks that share…

图像与视频处理 · 电气工程与系统科学 2022-09-13 Numan Saeed , Ikboljon Sobirov , Roba Al Majzoub , Mohammad Yaqub

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

图像与视频处理 · 电气工程与系统科学 2024-12-31 Elhoucine Elfatimi , Pratik Shah

In this paper, we describe a dataset relating to cellular and physical conditions of patients who are operated upon to remove colorectal tumours. This data provides a unique insight into immunological status at the point of tumour removal,…

机器学习 · 计算机科学 2016-11-17 Chris Roadknight , Uwe Aickelin , Guoping Qiu , John Scholefield , Lindy Durrant

Colorectal cancer liver metastasis (CRLM) exhibits high postoperative recurrence and pronounced prognostic heterogeneity, challenging individualized management. Existing prognostic approaches often rely on static representations from a…

图像与视频处理 · 电气工程与系统科学 2026-04-09 Wei Yang , Yiran Zhu , Yan su , Zesheng Li , Chengchang Pan , Honggang Qi

Skin conditions are reported the 4th leading cause of nonfatal disease burden worldwide. However, given the colossal spectrum of skin disorders defined clinically and shortage in dermatology expertise, diagnosing skin conditions in a timely…

计算机视觉与模式识别 · 计算机科学 2020-07-15 Junyan Wu , Hao Jiang , Xiaowei Ding , Anudeep Konda , Jin Han , Yang Zhang , Qian Li

There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved…

定量方法 · 定量生物学 2022-12-15 Olalekan Ogundipe , Zeyneb Kurt , Wai Lok Woo

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

机器学习 · 计算机科学 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

Despite the fact that cancer survivability rates vary greatly between stages, traditional survival prediction models have frequently been trained and assessed using examples from all combined phases of the disease. This method may result in…

机器学习 · 计算机科学 2026-01-08 Parisa Poorhasani , Bogdan Iancu

Skin conditions affect an estimated 1.9 billion people worldwide. A shortage of dermatologists causes long wait times and leads patients to seek dermatologic care from general practitioners. However, the diagnostic accuracy of general…

Deep Neural Networks have shown promising classification performance when predicting certain biomarkers from Whole Slide Images in digital pathology. However, the calibration of the networks' output probabilities is often not evaluated.…

图像与视频处理 · 电气工程与系统科学 2023-12-18 Alexander Kurz , Hendrik A. Mehrtens , Tabea-Clara Bucher , Titus J. Brinker

Cancer histology reveals disease progression and associated molecular processes, and contains rich phenotypic information that is predictive of outcome. In this paper, we developed a computational approach based on deep learning to predict…

图像与视频处理 · 电气工程与系统科学 2019-09-20 Saima Rathore , Muhammad Aksam Iftikhar , Zissimos Mourelatos

Objective: Deep Learning-based Radiomics (DLR) has achieved great success in medical image analysis and has been considered a replacement for conventional radiomics that relies on handcrafted features. In this study, we aimed to explore the…

图像与视频处理 · 电气工程与系统科学 2022-09-20 Bingxin Gu , Mingyuan Meng , Lei Bi , Jinman Kim , David Dagan Feng , Shaoli Song