中文
相关论文

相关论文: Biomedical Information Extraction for Disease Gene…

200 篇论文

Information extraction (IE) is an important task in Natural Language Processing (NLP), involving the extraction of named entities and their relationships from unstructured text. In this paper, we propose a novel approach to this task by…

计算与语言 · 计算机科学 2024-04-22 Urchade Zaratiana , Nadi Tomeh , Niama El Khbir , Pierre Holat , Thierry Charnois

Knowledge about protein-protein interactions is essential in understanding the biological processes such as metabolic pathways, DNA replication, and transcription etc. However, a majority of the existing Protein-Protein Interaction (PPI)…

信息检索 · 计算机科学 2018-07-09 Shweta Yadav , Ankit Kumar , Asif Ekbal , Sriparna Saha , Pushpak Bhattacharyya

Biomedical knowledge graphs (KGs) are vital for drug discovery and clinical decision support but remain incomplete. Large language models (LLMs) excel at extracting biomedical relations, yet their outputs lack standardization and alignment…

信息检索 · 计算机科学 2025-12-01 Olawumi Olasunkanmi , Mathew Satusky , Hong Yi , Chris Bizon , Harlin Lee , Stanley Ahalt

The intrinsic complexity of human biology presents ongoing challenges to scientific understanding. Researchers collaborate across disciplines to expand our knowledge of the biological interactions that define human life. AI methodologies…

Medication Extraction and Mining play an important role in healthcare NLP research due to its practical applications in hospital settings, such as their mapping into standard clinical knowledge bases (SNOMED-CT, BNF, etc.). In this work, we…

计算与语言 · 计算机科学 2024-12-31 Pablo Romero , Lifeng Han , Goran Nenadic

In recent years, there has been an increasing number of frameworks developed for biomedical entity and relation extraction. This research effort aims to address the accelerating growth in biomedical publications and the intricate nature of…

计算与语言 · 计算机科学 2024-08-14 Minh Nguyen , Phuong Le

Published biomedical information has and continues to rapidly increase. The recent advancements in Natural Language Processing (NLP), have generated considerable interest in automating the extraction, normalization, and representation of…

计算与语言 · 计算机科学 2024-04-24 Armando D. Diaz Gonzalez , Kevin S. Hughes , Songhui Yue , Sean T. Hayes

With the advent of artificial intelligence (AI), many researchers are attempting to extract structured information from document-level biomedical literature by fine-tuning large language models (LLMs). However, they face significant…

神经与进化计算 · 计算机科学 2026-02-26 Lei Zhao , Ling Kang , Quan Guo

Drug discovery (DD) has tremendously contributed to maintaining and improving public health. Hypothesizing that inhibiting protein misfolding can slow disease progression, researchers focus on target identification (Target ID) to find…

定量方法 · 定量生物学 2025-01-29 Ziwen Li , Xiang 'Anthony' Chen , Youngseung Jeon

Clinical trials predicate subject eligibility on a diversity of criteria ranging from patient demographics to food allergies. Trials post their requirements as semantically complex, unstructured free-text. Formalizing trial criteria to a…

计算与语言 · 计算机科学 2020-07-29 Yitong Tseo , M. I. Salkola , Ahmed Mohamed , Anuj Kumar , Freddy Abnousi

Backgrounds: Information extraction (IE) is critical in clinical natural language processing (NLP). While large language models (LLMs) excel on generative tasks, their performance on extractive tasks remains debated. Methods: We…

In this research, we present our work participation for the DrugProt task of BioCreative VII challenge. Drug-target interactions (DTIs) are critical for drug discovery and repurposing, which are often manually extracted from the…

计算与语言 · 计算机科学 2021-11-09 Jehad Aldahdooh , Ziaurrehman Tanoli , Jing Tang

Biological relation networks contain rich information for understanding the biological mechanisms behind the relationship of entities such as genes, proteins, diseases, and chemicals. The vast growth of biomedical literature poses…

计算与语言 · 计算机科学 2025-01-27 Po-Ting Lai , Chih-Hsuan Wei , Shubo Tian , Robert Leaman , Zhiyong Lu

Detecting protein-protein interactions (PPIs) is crucial for understanding genetic mechanisms, disease pathogenesis, and drug design. However, with the fast-paced growth of biomedical literature, there is a growing need for automated and…

计算与语言 · 计算机科学 2023-12-14 Hasin Rehana , Nur Bengisu Çam , Mert Basmaci , Jie Zheng , Christianah Jemiyo , Yongqun He , Arzucan Özgür , Junguk Hur

Motivation: The biomedical literature contains a wealth of chemical-protein interactions (CPIs). Automatically extracting CPIs described in biomedical literature is essential for drug discovery, precision medicine, as well as basic…

计算与语言 · 计算机科学 2020-04-27 Cong Sun , Zhihao Yang , Leilei Su , Lei Wang , Yin Zhang , Hongfei Lin , Jian Wang

Drug-drug interaction (DDI) is a vital information when physicians and pharmacists intend to co-administer two or more drugs. Thus, several DDI databases are constructed to avoid mistakenly combined use. In recent years, automatically…

计算与语言 · 计算机科学 2017-05-19 Zibo Yi , Shasha Li , Jie Yu , Qingbo Wu

There are a few challenges related to the task of biomedical named entity recognition, which are: the existing methods consider a fewer number of biomedical entities (e.g., disease, symptom, proteins, genes); and these methods do not…

计算与语言 · 计算机科学 2022-07-05 Shaina Raza , Brian Schwartz

Document-level information extraction (IE) is a crucial task in natural language processing (NLP). This paper conducts a systematic review of recent document-level IE literature. In addition, we conduct a thorough error analysis with…

计算与语言 · 计算机科学 2023-09-26 Hanwen Zheng , Sijia Wang , Lifu Huang

In recent years extracting relevant information from biomedical and clinical texts such as research articles, discharge summaries, or electronic health records have been a subject of many research efforts and shared challenges. Relation…

计算与语言 · 计算机科学 2016-07-01 Sunil Kumar Sahu , Ashish Anand , Krishnadev Oruganty , Mahanandeeshwar Gattu

Relation Extraction (RE) is the task of extracting semantic relationships between entities in a sentence and aligning them to relations defined in a vocabulary, which is generally in the form of a Knowledge Graph (KG) or an ontology.…

计算与语言 · 计算机科学 2023-09-06 Monika Jain , Kuldeep Singh , Raghava Mutharaju