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Modern high-throughput sequencing technologies have enabled us to profile multiple molecular modalities from the same single cell, providing unprecedented opportunities to assay celluar heterogeneity from multiple biological layers.…

机器学习 · 统计学 2022-05-20 Pengcheng Zeng , Zhixiang Lin

Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry Imaging (MSI) is a powerful technique for spatially resolved molecular profiling and cancer biomarker discovery. Recent advances, including a novel multiomics workflow, enable…

统计方法学 · 统计学 2025-09-03 Francesco Denti , Cecilia Balocchi , Vanna Denti , Giulia Capitoli

Determination of fundamental mechanisms of disease often hinges on histopathology visualization and quantitative image analysis. Currently, the analysis of multi-channel fluorescence tissue images is primarily achieved by manual…

Accurate synthesis of a full 3D MR image containing tumours from available MRI (e.g. to replace an image that is currently unavailable or corrupted) would provide a clinician as well as downstream inference methods with important…

计算机视觉与模式识别 · 计算机科学 2018-07-31 Raghav Mehta , Tal Arbel

Resting state fMRI is an imaging modality which reveals brain activity localization through signal changes, in what is known as Resting State Networks (RSNs). This technique is gaining popularity in neurosurgical pre-planning to visualize…

机器学习 · 计算机科学 2022-09-22 Sejal Ghate , Alberto Santamaria-Pang , Ivan Tarapov , Haris I Sair , Craig K Jones

Combining experiments with artificial intelligence algorithms, we propose a new machine learning based approach to extract the cellular force distributions from the microscope images. The full process can be divided into three steps. First,…

The mainstream CNN-based remote sensing (RS) image semantic segmentation approaches typically rely on massive labeled training data. Such a paradigm struggles with the problem of RS multi-view scene segmentation with limited labeled views…

计算机视觉与模式识别 · 计算机科学 2023-08-09 Zipeng Qi , Hao Chen , Chenyang Liu , Zhenwei Shi , Zhengxia Zou

In this work, we describe a method for large-scale 3D cell-tracking through a segmentation selection approach. The proposed method is effective at tracking cells across large microscopy datasets on two fronts: (i) It can solve problems…

计算机视觉与模式识别 · 计算机科学 2024-04-15 Jordão Bragantini , Merlin Lange , Loïc Royer

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Medical Ultrasound (US) imaging has seen increasing demands over the past years, becoming one of the most preferred imaging modalities in clinical practice due to its affordability, portability, and real-time capabilities. However, it faces…

The rapid on-site evaluation (ROSE) technique can significantly ac-celerate the diagnostic workflow of pancreatic cancer by immediately analyzing the fast-stained cytopathological images with on-site pathologists. Computer-aided diagnosis…

图像与视频处理 · 电气工程与系统科学 2022-06-08 Tianyi Zhang , Youdan Feng , Yunlu Feng , Guanglei Zhang

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

图像与视频处理 · 电气工程与系统科学 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

Microscopy image analysis is fundamental for different applications, from diagnosis to synthetic engineering and environmental monitoring. Modern acquisition systems have granted the possibility to acquire an escalating amount of images,…

计算机视觉与模式识别 · 计算机科学 2025-06-26 Jacopo Dapueto , Vito Paolo Pastore , Nicoletta Noceti , Francesca Odone

Lesion segmentation, in contrast to natural scene segmentation, requires handling subtle variations in texture and color, frequent imaging artifacts (such as hairs, rulers, and bubbles), and a critical need for precise boundary localization…

计算机视觉与模式识别 · 计算机科学 2026-05-11 Vikram Singh , Kabir Malhotra , Rohan Desai , Ananya Shankaracharya , Priyadarshini Chatterjee , Krishnan Menon Iyer

Segmentation of colorectal cancerous regions from 3D Magnetic Resonance (MR) images is a crucial procedure for radiotherapy which conventionally requires accurate delineation of tumour boundaries at an expense of labor, time and…

计算机视觉与模式识别 · 计算机科学 2021-05-25 Yi-Jie Huang , Qi Dou , Zi-Xian Wang , Li-Zhi Liu , Ying Jin , Chao-Feng Li , Lisheng Wang , Hao Chen , Rui-Hua Xu

Real-time monitoring of dynamic biological processes in the body is critical to understanding disease progression and treatment response. This data, for instance, can help address the lower than 50% response rates to cancer immunotherapy.…

Rapid growth in the development of medical imaging analysis technology has been propelled by the great interest in improving computer-aided diagnosis and detection (CAD) systems for three popular image visualization tasks: classification,…

计算机视觉与模式识别 · 计算机科学 2022-03-03 Manu Goyal , Moi Hoon Yap , Saeed Hassanpour

Malignant melanoma has one of the most rapidly increasing incidences in the world and has a considerable mortality rate. Early diagnosis is particularly important since melanoma can be cured with prompt excision. Dermoscopy images play an…

计算机视觉与模式识别 · 计算机科学 2017-03-20 Lei Bi , Jinman Kim , Euijoon Ahn , Dagan Feng

Gene panel selection aims to identify the most informative genomic biomarkers in label-free genomic datasets. Traditional approaches, which rely on domain expertise, embedded machine learning models, or heuristic-based iterative…

基因组学 · 定量生物学 2025-09-12 Meng Xiao , Weiliang Zhang , Xiaohan Huang , Hengshu Zhu , Min Wu , Xiaoli Li , Yuanchun Zhou

We propose a method to accurately obtain the ratio of tumor cells over an entire histological slide. We use deep fully convolutional neural network models trained to detect and classify cells on images of H&E-stained tissue sections.…

图像与视频处理 · 电气工程与系统科学 2021-01-29 Eric Cosatto , Kyle Gerard , Hans-Peter Graf , Maki Ogura , Tomoharu Kiyuna , Kanako C. Hatanaka , Yoshihiro Matsuno , Yutaka Hatanaka
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