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Patient-specific cardiac computational models are essential for the efficient realization of precision medicine and in-silico clinical trials using digital twins. Cardiac digital twins can provide non-invasive characterizations of cardiac…

计算机视觉与模式识别 · 计算机科学 2022-08-09 Lei Li , Julia Camps , Abhirup Banerjee , Marcel Beetz , Blanca Rodriguez , Vicente Grau

Digital twins for cardiac electrophysiology are an enabling technology for precision cardiology. Current forward models are advanced enough to simulate the cardiac electric activity under different pathophysiological conditions and…

最优化与控制 · 数学 2025-05-05 Thomas Grandits , Karli Gillette , Gernot Plank , Simone Pezzuto

We propose a method for identifying an ectopic activation in the heart non-invasively. Ectopic activity in the heart can trigger deadly arrhythmias. The localization of the ectopic foci or earliest activation sites (EASs) is therefore a…

信号处理 · 电气工程与系统科学 2022-03-15 Simone Pezzuto , Paris Perdikaris , Francisco Sahli Costabal

This work is dedicated to the simulation of full cycles of the electrical activity of the heart and the corresponding body surface potential. The model is based on a realistic torso and heart anatomy, including ventricles and atria. One of…

医学物理 · 物理学 2015-09-04 Elisa Schenone , Annabelle Collin , Jean-Frédéric Gerbeau

An electrocardiogram (EKG) is a common, non-invasive test that measures the electrical activity of a patient's heart. EKGs contain useful diagnostic information about patient health that may be absent from other electronic health record…

Image-based computational models of the heart represent a powerful tool to shed new light on the mechanisms underlying physiological and pathological conditions in cardiac function and to improve diagnosis and therapy planning. However, in…

Cardiac digital twins (CDTs) have the potential to offer individualized evaluation of cardiac function in a non-invasive manner, making them a promising approach for personalized diagnosis and treatment planning of my-ocardial infarction…

信号处理 · 电气工程与系统科学 2024-02-16 Lei Li , Julia Camps , Zhinuo , Wang , Abhirup Banerjee , Marcel Beetz , Blanca Rodriguez , Vicente Grau

Abnormal patterns of ventricular repolarisation contribute to lethal arrhythmias in various cardiac conditions, including inherited and acquired channelopathies, cardiomyopathies, and ischaemic heart disease. However, methods to detect…

医学物理 · 物理学 2025-06-30 James A Coleman , Julia Camps , Abdallah I Hasaballa , Alfonso Bueno-Orovio

The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…

医学物理 · 物理学 2023-08-03 Sebastian Skatulla , Carlo Sansour , Mary Familusi , Jagir Hussan , Ntobeko Ntusi

We present PhysECG: a physically motivated projection of the 12 lead electrocardiogram, supported by a deep learning model trained on 21,799 recordings from the PTB-XL database and discuss its feasibility. The method allows to evaluate the…

Electrocardiogram (ECG) is one of the non-invasive and low-risk methods to monitor the condition of the human heart. Any abnormal pattern(s) in the ECG signal is an indicative measure of malfunctioning of the heart, termed as arrhythmia.…

信号处理 · 电气工程与系统科学 2018-10-10 Sai Manoj Pudukotai Dinakarrao , Matthias Wess

In the process of patient diagnosis, non-invasive measurements are widely used due to their low risks and quick results. Electrocardiogram (ECG), as a non-invasive method to collect heart activities, is used to diagnose cardiac conditions.…

机器学习 · 计算机科学 2025-12-11 Yuhao Xu , Jiaying Lu , Sirui Ding , Defu Cao , Xiao Hu , Carl Yang

Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…

机器学习 · 计算机科学 2025-12-09 Hanhui Deng , Xinglin Li , Jie Luo , Di Wu

Electrocardiography (ECG) plays a significant role in diagnosing heart-related issues, it provides, accurate, fast, and dependable insights into crucial parameters like QRS complex duration, the R-R interval, and the occurrence, amplitude,…

信号处理 · 电气工程与系统科学 2023-07-24 Kavya Remesh , Job Chunkath

Over the course of the past two decades, a substantial body of research has substantiated the viability of utilising cardiac signals as a biometric modality. This paper presents a novel approach for patient identification in healthcare…

机器学习 · 计算机科学 2024-11-27 Caterina Fuster-Barceló , Carmen Cámara , Pedro Peris-López

Performing inference over simulators is generally intractable as their runtime means we cannot compute a marginal likelihood. We develop a likelihood-free inference method to infer parameters for a cardiac simulator, which replicates…

机器学习 · 统计学 2017-12-12 Adam McCarthy , Blanca Rodriguez , Ana Minchole

This paper presents a computational solution that enables continuous cardiac monitoring through cross-modality inference of electrocardiogram (ECG). While some smartwatches now allow users to obtain a 30-second ECG test by tapping a…

信号处理 · 电气工程与系统科学 2024-05-20 Yuenan Li , Xin Tian , Qiang Zhu , Min Wu

Ensuring timely and accurate diagnosis of medical conditions is paramount for effective patient care. Electrocardiogram (ECG) signals are fundamental for evaluating a patient's cardiac health and are readily available. Despite this, little…

信号处理 · 电气工程与系统科学 2025-11-21 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Timely access to laboratory values is critical for clinical decision-making, yet current approaches rely on invasive venous sampling and are intrinsically delayed. Electrocardiography (ECG), as a non-invasive and widely available signal,…

机器学习 · 计算机科学 2025-10-28 Yujie Xiao , Gongzhen Tang , Wenhui Liu , Jun Li , Guangkun Nie , Zhuoran Kan , Deyun Zhang , Qinghao Zhao , Shenda Hong

Virtual heart models have been proposed to enhance the safety of implantable cardiac devices through closed loop validation. To communicate with a virtual heart, devices have been driven by cardiac signals at specific sites. As a result,…

系统与控制 · 计算机科学 2017-03-06 Weiwei Ai , Nitish Patel , Partha Roop , Avinash Malik , Nathan Allen , Mark L. Trew
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