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Functional connectivity (FC) has become a primary means of understanding brain functions by identifying brain network interactions and, ultimately, how those interactions produce cognitions. A popular definition of FC is by statistical…

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

图像与视频处理 · 电气工程与系统科学 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

Schizophrenia (SZ) is a brain disorder leading to detached mind's normally integrated processes. Hence, the exploration of the symptoms in relation to functional connectivity (FC) had great relevance in the field. FC can be investigated on…

神经元与认知 · 定量生物学 2026-04-08 Davide Coluzzi , Giuseppe Baselli

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

神经元与认知 · 定量生物学 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Alzheimer's disease (AD) is a neurodegenerative disease known to affect brain functional connectivity (FC). Linear FC measures have been applied to study the differences in AD by splitting neurophysiological signals such as…

神经元与认知 · 定量生物学 2022-06-14 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

神经元与认知 · 定量生物学 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

应用统计 · 统计学 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Predicting disease states from functional brain connectivity is critical for the early diagnosis of severe neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease. Existing studies commonly employ Graph Neural…

机器学习 · 计算机科学 2025-04-22 David Yang , Mostafa Abdelmegeed , John Modl , Minjeong Kim

Most generally, dynamic functional connectivity (FC) refers to the non-instantaneous couplings across timeseries from a set of brain areas, here as measured by fMRI. This is in contrast to static FC, which is defined as purely instantaneous…

神经元与认知 · 定量生物学 2023-01-10 Christine Ahrends , Diego Vidaurre

The available evidence suggests that dynamic functional connectivity (dFC) can capture time-varying abnormalities in brain activity in resting-state cerebral functional magnetic resonance imaging (rs-fMRI) data and has a natural advantage…

神经元与认知 · 定量生物学 2023-09-13 Cheng Zhu , Ying Tan , Shuqi Yang , Jiaqing Miao , Jiayi Zhu , Huan Huang , Dezhong Yao , Cheng Luo

Functional magnetic resonance imaging (fMRI) data have become increasingly available and are useful for describing functional connectivity (FC), the relatedness of neuronal activity in regions of the brain. This FC of the brain provides…

机器学习 · 统计学 2020-10-14 Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan , Lin Zhang

Alzheimer's disease (AD) is the most prevalent form of dementia. Traditional methods cannot achieve efficient and accurate diagnosis of AD. In this paper, we introduce a novel method based on dynamic functional connectivity (dFC) that can…

计算机视觉与模式识别 · 计算机科学 2020-06-25 Xingwei An , Yutao Zhou , Yang Di , Dong Ming

Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

应用统计 · 统计学 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

统计方法学 · 统计学 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Human brain functional connectivity (FC) is often measured as the similarity of functional MRI responses across brain regions when a brain is either resting or performing a task. This paper aims to statistically analyze the dynamic nature…

计算机视觉与模式识别 · 计算机科学 2024-10-30 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Functional connectivity plays an essential role in modern neuroscience. The modality sheds light on the brain's functional and structural aspects, including mechanisms behind multiple pathologies. One such pathology is schizophrenia which…

神经元与认知 · 定量生物学 2022-06-07 Maksim Zhdanov , Saskia Steinmann , Nico Hoffmann

Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activities, and can be very useful in the studies of brain…

图像与视频处理 · 电气工程与系统科学 2025-01-29 Jing Zhang , Yanjun Lyu , Xiaowei Yu , Lu Zhang , Chao Cao , Tong Chen , Minheng Chen , Yan Zhuang , Tianming Liu , Dajiang Zhu

This paper studies the link between resting-state functional connectivity (FC), measured by the correlations of the fMRI BOLD time courses, and structural connectivity (SC), estimated through fiber tractography. Instead of a static analysis…

Coronary heart disease (CHD) arises from complex interactions among uncontrollable factors, controllable lifestyle factors, and clinical indicators, where relationships are often uncertain. Fuzzy subgraph connectivity (FSC) provides a…

人工智能 · 计算机科学 2025-09-23 Shanookha Ali , Nitha Niralda P C

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

神经元与认知 · 定量生物学 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das
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