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Single molecule localization microscopy (SMLM) techniques enable imaging biological samples well beyond the diffraction limit of light, but they vary significantly in their spatial and temporal resolutions. High-order statistical analysis…

生物物理 · 物理学 2016-03-15 Shachar Schidorsky , Xiyu Yi , Yair Razvag , Yonatan Golan , Shimon Weiss , Eilon Sherman

Multiple stains are usually used to highlight biological substances in biomedical image analysis. To decompose multiple stains for co-localization quantification, blind source separation is usually performed. Prior model-based stain…

图像与视频处理 · 电气工程与系统科学 2021-02-16 Xingyu Li

Over the past two decades there have been tremendous advances in high-power fiber lasers, which have provided a powerful tool for science, engineering and defense. A major roadblock for further power scaling of single-frequency fiber laser…

Self-supervised video denoising aims to remove noise from videos without relying on ground truth data, leveraging the video itself to recover clean frames. Existing methods often rely on simplistic feature stacking or apply optical flow…

计算机视觉与模式识别 · 计算机科学 2024-12-17 Zikang Chen , Tao Jiang , Xiaowan Hu , Wang Zhang , Huaqiu Li , Haoqian Wang

Three-dimensional fluorescence microscopy often suffers from anisotropy, where the resolution along the axial direction is lower than that within the lateral imaging plane. We address this issue by presenting Dual-Cycle, a new framework for…

图像与视频处理 · 电气工程与系统科学 2022-09-26 Tomas Kerepecky , Jiaming Liu , Xue Wen Ng , David W. Piston , Ulugbek S. Kamilov

Super-resolution microscopy normally requiring complex and cumbersome optics is not applicable for in situ imaging through a narrow channel. Here, we demonstrate single hair-thin multimode fiber (MMF) endoscope (less than 250 ${\mu}m$) for…

Controlling the longitudinal phase space of high-brightness relativistic electron beams is crucial for advancing a broad spectrum of charged-particle-based instrumentation and scientific frontiers. A generalized method for achieving this…

We present an ultra-thin hybrid imaging system based on an optical multimode fiber (MMF) and an optical fiber hydrophone that combines optical resolution photoacoustic and fluorescence microscopy. To control the illumination at the distal…

Laser beams with high optical power propagating in a Kerr medium can undergo self-focusing when their power exceeds a critical power determined by the optical properties of the medium. The highly concentrated energy close to the in the…

光学 · 物理学 2026-04-22 Jiaqi Wang , Yang Xu , Saumya Choudhary , Omid Mozafar , Robert Boyd

Deep cosmic microwave background polarization experiments allow a very precise internal reconstruction of the gravitational lensing signal in pricinple. For this aim, likelihood-based or Bayesian methods are typically necessary, where very…

宇宙学与河外天体物理 · 物理学 2023-10-25 Martin Reinecke , Sebastian Belkner , Julien Carron

Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…

图像与视频处理 · 电气工程与系统科学 2024-03-07 Olivier Leblanc , Mathias Hofer , Siddharth Sivankutty , Hervé Rigneault , Laurent Jacques

Progress in neuroscience constantly relies on the development of new techniques to investigate the complex dynamics of neuronal networks. An ongoing challenge is to achieve minimally-invasive and high-resolution observations of neuronal…

Unsupervised/self-supervised time series representation learning is a challenging problem because of its complex dynamics and sparse annotations. Existing works mainly adopt the framework of contrastive learning with the time-based…

机器学习 · 计算机科学 2022-05-31 Ling Yang , Shenda Hong

Airy beams, celebrated for their self-acceleration, diffraction-free propagation, and self-healing properties, have garnered significant interest in optics and photonics, with applications spanning ultrafast optics, laser processing,…

光学 · 物理学 2025-06-09 Zhaofeng Huang , Xiaolin Su , Qian Cao , Andy Chong , Qiwen Zhan

We propose non-phase-matched sum frequency generation (SFG) as a method for characterizing broadband multimode light. We demonstrate its advantages using high-gain parametric down conversion (PDC) as an example. By generating the sum…

量子物理 · 物理学 2019-05-22 Denis A. Kopylov , Kirill Yu. Spasibko , Tatiana V. Murzina , Maria V. Chekhova

Pretraining vision transformers (ViT) with attention guided masked image modeling (MIM) has shown to increase downstream accuracy for natural image analysis. Hierarchical shifted window (Swin) transformer, often used in medical image…

计算机视觉与模式识别 · 计算机科学 2024-07-04 Jue Jiang , Aneesh Rangnekar , Chloe Min Seo Choi , Harini Veeraraghavan

In this Letter, we show theoretically that the nonlinear photoionisation process of a noble gas inside a hollow-core photonic crystal fibre can be exploited in obtaining broadband supercontinuum generation via pumping close to the…

光学 · 物理学 2021-04-15 Mohammed F. Saleh , Fabio Biancalana

As a typical self-paced brain-computer interface (BCI) system, the motor imagery (MI) BCI has been widely applied in fields such as robot control, stroke rehabilitation, and assistance for patients with stroke or spinal cord injury. Many…

定量方法 · 定量生物学 2023-10-31 Xiong Xiong , Ying Wang , Tianyuan Song , Jinguo Huang , Guixia Kang

Multifocal microscopy (MFM) offers high-speed three-dimensional imaging through the simultaneous image capture from multiple focal planes. Conventional MFM systems use a fabricated grating in the emission path for a single emission…

生物物理 · 物理学 2019-07-31 M. Junaid Amin , Sabine Petry , Haw Yang , Joshua W. Shaevitz

Imaging through optical multimode fibers (MMFs) has the potential to enable hair-thin endoscopes that reduce the invasiveness of imaging deep inside tissues and organs. Current approaches predominantly require active wavefront shaping and…

光学 · 物理学 2021-12-13 Szu-Yu Lee , Vicente J. Parot , Brett E. Bouma , Martin Villiger