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We use molecules to couple light into and out of microscale plasmonic waveguides. Energy transfer, mediated by surface plasmons, from donor molecules to acceptor molecules over ten micrometer distances is demonstrated. Also surface plasmon…

Antimicrobial biomaterials are critical to aid in the regeneration of oral soft tissue and prevent or treat localised bacterial infections. With the rising trend in antibiotic resistance, there is a pressing clinical need for new…

组织与器官 · 定量生物学 2021-01-06 Amy Contreras , Michael J. Raxworthy , Simon Wood , Jessica D. Schiffman , Giuseppe Tronci

Cytoskeletal networks are foundational examples of active matter and central to self-organized structures in the cell. In vivo, these networks are active and heavily crosslinked. Relating their large-scale dynamics to properties of their…

Experimental mechanisms that yield the growth of homochiral copolymers over their heterochiral counterparts have been advocated by Lahav and co-workers. These chiral amplification mechanisms proceed through racemic {\beta}-sheet-controlled…

定量方法 · 定量生物学 2012-12-19 Celia Blanco , David Hochberg

Biomolecular motor proteins that generate forces by consuming chemical energy obtained from ATP hydrolysis are pivotal for organizing broad cytoskeletal structures in living cells. The control of such cytoskeletal structures benefits…

软凝聚态物质 · 物理学 2021-12-30 Shunya Araki , Kazusa Beppu , Arif Md. Rashedul Kabir , Akira Kakugo , Yusuke T. Maeda

Model-driven analysis of biophysical phenomena is gaining increased attention and utility for medical imaging applications. In magnetic resonance imaging (MRI), the availability of well-established models for describing the relations…

医学物理 · 物理学 2023-10-31 Dinor Nagar , Nikita Vladimirov , Christian T. Farrar , Or Perlman

Machine learning is increasingly recognized as a promising technology in the biological, biomedical, and behavioral sciences. There can be no argument that this technique is incredibly successful in image recognition with immediate…

In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies. Typically blood flows…

流体动力学 · 物理学 2011-10-06 Markus Gusenbauer , Ivan Cimrak , Simon Bance , Lukas Exl , Franz Reichel , Harald Oezelt , Thomas Schrefl

Developing successful scaffolds requires clinicians to adopt a multidisciplinary approach in order to understand and stimulate the natural bone regeneration process. A variety of natural and synthetic biomaterials, including naturally…

组织与器官 · 定量生物学 2016-10-28 Elaine R. Durham , Giuseppe Tronci , Xuebin Yang , David J. Wood , Stephen J. Russell

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains…

Improving the detailed understanding of the underlying properties and functions of biomolecules has recently attracted growing interest, enabled by the possibility of real-space imaging of single, intact macromolecules using Scanning…

介观与纳米尺度物理 · 物理学 2026-03-10 Tim J. Seifert , Dhaneesh Kumar , Markus Etzkorn , Stephan Rauschenbach , Klaus Kern , Kelvin Anggara , Uta Schlickum

Self-assembly is the autonomous organization of components into patterns or structures: an essential ingredient of biology and a desired route to complex organization. At equilibrium, the structure is encoded through specific interactions,…

软凝聚态物质 · 物理学 2018-10-03 Antoine Aubret , Mena Youssef , Stefano Sacanna , Jérémie Palacci

The fabrication of multilayered heterostructures is essential for advancing microelectronic and biosensing technologies. Conventional top-down manufacturing techniques are often cost-prohibitive and unsuitable for biomedical applications.…

化学物理 · 物理学 2025-06-13 Anand Dev Ranjan , Suyash Narayan Amzare , Subhrokoli Ghosh , Ayan Banerjee

As an effective method to deliver external materials into biological cells, microinjection has been widely applied in the biomedical field. However, the cognition of cell mechanical property is still inadequate, which greatly limits the…

机器人学 · 计算机科学 2022-11-29 Shengzheng Kang , Zhicheng Song , Xiaolong Yang , Yao Li , Hongtao Wu , Tao Li

Active metasurfaces enable dynamic control of light for applications in beam steering, pixelated holography, and adaptive optics, but demonstrations of two-dimensional (2D) electrically addressable arrays have so far been limited. Here we…

The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals received from their environment, is crucial for the functioning of all biological systems. In experiments, cells placed on cyclically…

生物物理 · 物理学 2019-01-17 John J. Molina , Ryoichi Yamamoto

Obtaining a rigorous and reliable method for linking computer simulations of polymer blends and composites at different length scales of interest is a highly desirable goal in soft matter physics. In this paper a multiscale modeling…

软凝聚态物质 · 物理学 2015-05-19 J. McCarty , M. G. Guenza

The process of self-assembly is guided by the minimization of free energy, which limits the symmetries available for assembly and ultimately the usefulness of devices fabricated in this fashion. Here, we demonstrate experimentally for the…

We investigate the behavior of self-propelled particles under cyclic stretching, inspired by the characteristic pattern dynamics observed in microtubule (MT) motility assays subjected to uniaxial cyclic substrate stretching. We develop a…

软凝聚态物质 · 物理学 2025-05-27 Takumi Tagaki , Seiya Nishikawa , Shuji Ishihara

Cells are known to sense and respond to their mechanical microenvironment in profound ways. Various evidence has implicated the adhesome, a body of adhesion associated proteins, in several cell fate decisions, including differentiation and…

细胞行为 · 定量生物学 2020-05-12 Zachary Reitz