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This paper reports on advances in optical coherence tomography (OCT) for application in dermatology. Full-field OCT is a particular approach of OCT based on white-light interference microscopy. FF-OCT produces en face tomographic images by…

医学物理 · 物理学 2018-04-06 Olivier Levecq , Arthur Davis , Hicham Azimani , David Siret , Jean-Luc Perrot , Arnaud Dubois

Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables non-destructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR)…

光学 · 物理学 2020-07-15 Ivan Zorin , Rong Su , Bettina Heise , Bernhard Lendl , Markus Brandstetter

Using spectrally correlated photon pairs instead of classical laser light and coincidence detection instead of light intensity detection, Quantum Optical Coherence Tomography (Q-OCT) outperforms classical OCT in several experimental terms.…

量子物理 · 物理学 2025-10-06 Sylwia M. Kolenderska , Crislane Vieira de Brito , Piotr Kolenderski

The increasingly demand for machining accuracy and product quality excites a great interest in high-resolution non-destructive testing (NDT) methods, but spatial resolution of conventional high-energy computed tomography (CT) is limited to…

Interactions between atoms and lasers provide the potential for unprecedented control of quantum states. Fulfilling this potential requires detailed knowledge of frequency noise in optical oscillators with state-of-the-art stability. We…

原子物理 · 物理学 2015-06-15 Michael Bishof , Xibo Zhang , Michael J. Martin , Jun Ye

Optical coherence tomography (OCT) is a 3D imaging technique that was introduced in 1991 [Science 254, 1178 (1991); Applied Optics 31, 919 (1992)]. Since 2018 there has been growing interest in a new type of OCT scheme based on the use of…

Optical Coherence Tomography (OCT) is a key 3D imaging technology that provides micron scale depth resolution for bio-imaging. This resolution substantially surpasses what it typically achieved in Light Detection and Ranging (LiDAR) which…

光学 · 物理学 2022-07-27 Robbie Murray , Ashley Lyons

Optical coherence tomography (OCT) imaging from different camera devices causes challenging domain shifts and can cause a severe drop in accuracy for machine learning models. In this work, we introduce a minimal noise adaptation method…

计算机视觉与模式识别 · 计算机科学 2022-09-20 Valentin Koch , Olle Holmberg , Hannah Spitzer , Johannes Schiefelbein , Ben Asani , Michael Hafner , Fabian J Theis

Traditional full-field optical coherence tomography (FF-OCT) is effective for rapid cross-sectional imaging but often suffers from incoherent signals due to imbalanced light intensities between the sample and reference arms. While the…

光学 · 物理学 2024-10-17 Youlong Fan , Qingye Hu , Zhongping Wang , Zengming Zhang , Xiantao Wei

We demonstrate high-efficiency, shot-noise-limited differential photodetection with real-time signal conditioning, suitable for feedback-based quantum control of atomic systems. The detector system has quantum efficiency of 0.92, is…

光学 · 物理学 2016-08-31 F. Martin Ciurana , G. Colangelo , Robert J. Sewell , M. W. Mitchell

Conventional Fourier-domain Optical Coherence Tomography (FD-OCT) systems depend on resampling into wavenumber (k) domain to extract the depth profile. This either necessitates additional hardware resources or amplifies the existing…

光学 · 物理学 2025-09-24 Maryam Viqar , Erdem Sahin , Elena Stoykova , Violeta Madjarova

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Due to its noninvasive character, optical coherence tomography (OCT) has become a popular diagnostic method in clinical settings. However, the low-coherence interferometric imaging procedure is inevitably contaminated by heavy speckle…

图像与视频处理 · 电气工程与系统科学 2020-07-08 Yongqiang Huang , Wenjun Xia , Zexin Lu , Yan Liu , Hu Chen , Jiliu Zhou , Leyuan Fang , Yi Zhang

We report an optimized implementation of spectral-domain quantum optical coherence tomography (SD-QOCT) capable of acquiring axial scans (A-scans) of multilayer samples without in the absence of mechanical scanning, at an unprecedented…

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

医学物理 · 物理学 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

In this work we propose a ResNet-based universal method for speckle reduction in optical coherence tomography (OCT) images. The proposed model contains 3 main modules: Convolution-BN-ReLU, Branch and Residual module. Unlike traditional…

计算机视觉与模式识别 · 计算机科学 2019-03-25 Cai Ning , Shi Fei , Hu Dianlin , Chen Yang

High-numerical-aperture optical coherence tomography (OCT) enables sub-cellular imaging but faces a trade-off between lateral resolution and depth of focus. Computational refocusing can correct defocus in Fourier-domain OCT, yet its…

光学 · 物理学 2026-05-22 Yue Zhu , Shuichi Makita , Naoki Fukutake , Yoshiaki Yasuno

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

图像与视频处理 · 电气工程与系统科学 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

Optical coherence tomography (OCT) enables high-resolution and non-invasive 3D imaging of the human retina but is inherently impaired by speckle noise. This paper introduces a spatio-temporal denoising algorithm for OCT data on a B-scan…

计算机视觉与模式识别 · 计算机科学 2017-03-09 Franziska Schirrmacher , Thomas Köhler , Lennart Husvogt , James G. Fujimoto , Joachim Hornegger , Andreas K. Maier

In optical coherence tomography (OCT), axial resolution and signal-to-noise ratio (SNR) are typically viewed as uncoupled parameters. We show that this is only true for mirror-like surfaces, and that in diffuse scattering samples such as…

光学 · 物理学 2022-04-06 Danielle J. Harper , Benjamin J. Vakoc