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Many diseases, including cancer and chronic conditions, require extended treatment periods and long-term strategies. Machine learning and AI research focusing on electronic health records (EHRs) have emerged to address this need. Effective…

Understanding non-genetic determinants of cell fate is critical for developing and improving cancer therapies, as genetically identical cells can exhibit divergent outcomes under the same treatment conditions. In this work, we present a…

计算机视觉与模式识别 · 计算机科学 2026-03-18 Florian Bürger , Martim Dias Gomes , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Estimating the causal effect of time-varying treatments on survival outcomes is a challenging task in many domains, particularly in medicine where treatment protocols adapt over time. While recent advances in representation learning have…

机器学习 · 统计学 2025-05-06 Ayoub Abraich

Radiation response in cancer is shaped by complex, patient specific biology, yet current treatment strategies often rely on uniform dose prescriptions without accounting for tumor heterogeneity. In this study, we introduce a meta learning…

医学物理 · 物理学 2025-08-12 Hao Peng , Yuanyuan Zhang , Steve Jiang , Robert Timmerman , John Minna

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

计算与语言 · 计算机科学 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time.…

机器学习 · 统计学 2017-11-07 Hossein Soleimani , Adarsh Subbaswamy , Suchi Saria

Most existing time-to-event methods focus on either single-event or competing-risks settings, leaving multi-event scenarios relatively underexplored. In many healthcare applications, for example, a patient may experience multiple clinical…

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

医学物理 · 物理学 2020-06-17 Changhee Lee , Mihaela van der Schaar

Accurate prognosis for an individual patient is a key component of precision oncology. Recent advances in machine learning have enabled the development of models using a wider range of data, including imaging. Radiomics aims to extract…

Multimodal (MM) learning is emerging as a promising paradigm in biomedical artificial intelligence (AI) applications, integrating complementary modality, which highlight different aspects of patient health. The scarcity of large…

人工智能 · 计算机科学 2025-12-01 Niccolo Marini , Zhaohui Liang , Sivaramakrishnan Rajaraman , Zhiyun Xue , Sameer Antani

Accurate survival prediction is crucial for development of precision cancer medicine, creating the need for new sources of prognostic information. Recently, there has been significant interest in exploiting routinely collected clinical and…

机器学习 · 计算机科学 2021-03-23 Sejin Kim , Michal Kazmierski , Benjamin Haibe-Kains

Time Series Alignment is a critical task in signal processing with numerous real-world applications. In practice, signals often exhibit temporal shifts and scaling, making classification on raw data prone to errors. This paper introduces a…

机器学习 · 计算机科学 2025-02-27 Alireza Nourbakhsh , Hoda Mohammadzade

Accurate prediction of recurrence in clear cell renal cell carcinoma (ccRCC) remains a major clinical challenge due to the disease complex molecular, pathological, and clinical heterogeneity. Traditional prognostic models, which rely on…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Hasaan Maqsood , Saif Ur Rehman Khan

Medical diagnosis requires the effective synthesis of visual manifestations and clinical metadata. However, existing methods often treat metadata as isolated tags, failing to exploit the rich semantic knowledge embedded in clinical…

计算机视觉与模式识别 · 计算机科学 2026-02-27 Yiqing Wang , Chunming He , Ming-Chen Lu , Mercy Pawar , Leslie Niziol , Maria Woodward , Sina Farsiu

Mood disorders are common and associated with significant morbidity and mortality. Early diagnosis has the potential to greatly alleviate the burden of mental illness and the ever increasing costs to families and society. Mobile devices…

人机交互 · 计算机科学 2018-08-30 He Huang , Bokai Cao , Philip S. Yu , Chang-Dong Wang , Alex D. Leow

Lung cancer patients frequently experience breakthrough pain episodes, with up to 91% requiring timely intervention. To enable proactive pain management, we propose a hybrid machine learning and large language model pipeline that predicts…

Lung cancer, a leading cause of cancer-related deaths globally, emphasises the importance of early detection for better patient outcomes. Pulmonary nodules, often early indicators of lung cancer, necessitate accurate, timely diagnosis.…

计算机视觉与模式识别 · 计算机科学 2025-04-29 Jiahao Lu , Chong Yin , Silvia Ingala , Kenny Erleben , Michael Bachmann Nielsen , Sune Darkner

The longitudinal analysis of patient response time course following doses of therapeutics is currently performed using Pharmacokinetic/Pharmacodynamic (PK/PD) methodologies, which requires significant human experience and expertise in the…

机器学习 · 计算机科学 2021-06-24 James Lu , Brendan Bender , Jin Y. Jin , Yuanfang Guan

Foundation models (FMs) have demonstrated strong transferability across medical imaging tasks, yet their clinical utility depends critically on how pretrained representations are adapted to domain-specific data, supervision regimes, and…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

Accurate survival prediction is critical in oncology for prognosis and treatment planning. Traditional approaches often rely on a single data modality, limiting their ability to capture the complexity of tumor biology. To address this…

机器学习 · 计算机科学 2025-07-11 Alba Garrido , Alejandro Almodóvar , Patricia A. Apellániz , Juan Parras , Santiago Zazo