中文
相关论文

相关论文: SumGNN: Multi-typed Drug Interaction Prediction vi…

200 篇论文

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

人工智能 · 计算机科学 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

Interaction between pharmacological agents can trigger unexpected adverse events. Capturing richer and more comprehensive information about drug-drug interactions (DDI) is one of the key tasks in public health and drug development.…

机器学习 · 计算机科学 2020-10-19 Yuanfei Dai , Chenhao Guo , Wenzhong Guo , Carsten Eickhoff

Graph data, with its structurally variable nature, represents complex real-world phenomena like chemical compounds, protein structures, and social networks. Traditional Graph Neural Networks (GNNs) primarily utilize the message-passing…

机器学习 · 计算机科学 2025-02-05 Jianming Huang , Hiroyuki Kasai

Recommending safe and effective medication combinations from electronic health records (EHRs) is a core clinical AI problem, yet it remains difficult because patient trajectories are long, noisy, and clinically heterogeneous. Existing…

机器学习 · 计算机科学 2026-05-21 Krati Saxena , Tomohiro Shibata

This work investigates the challenge of learning and reasoning for Commonsense Question Answering given an external source of knowledge in the form of a knowledge graph (KG). We propose a novel graph neural network architecture, called…

计算与语言 · 计算机科学 2022-09-22 Chen Zheng , Parisa Kordjamshidi

Entity alignment is the task of finding entities representing the same real-world object in two knowledge graphs(KGs). Cross-lingual knowledge graph entity alignment aims to discover the cross-lingual links in the multi-language KGs, which…

计算与语言 · 计算机科学 2022-05-10 Shanqing Yu , Shihan Zhang , Jianlin Zhang , Jiajun Zhou , Qi Xuan , Bing Li , Xiaojuan Hu

Drug-drug interaction(DDI) prediction is an important task in the medical health machine learning community. This study presents a new method, multi-view graph contrastive representation learning for drug-drug interaction prediction,…

机器学习 · 计算机科学 2021-04-13 Yingheng Wang , Yaosen Min , Xin Chen , Ji Wu

Knowledge Graphs (KG) constitute a flexible representation of complex relationships between entities particularly useful for biomedical data. These KG, however, are very sparse with many missing edges (facts) and the visualisation of the…

人工智能 · 计算机科学 2016-12-08 Armando Vieira

In this work, we provide a new formulation for Graph Convolutional Neural Networks (GCNNs) for link prediction on graph data that addresses common challenges for biomedical knowledge graphs (KGs). We introduce a regularized attention…

机器学习 · 计算机科学 2018-12-04 Daniel Neil , Joss Briody , Alix Lacoste , Aaron Sim , Paidi Creed , Amir Saffari

With the emergence of multimodal electronic health records, the evidence for an outcome may be captured across multiple modalities ranging from clinical to imaging and genomic data. Predicting outcomes effectively requires fusion frameworks…

Knowledge graphs automatically constructed from text are increasingly used in real-world applications. However, their inherent noise, fragmentation, and semantic inconsistencies significantly affect the performance of Graph Neural Networks…

机器学习 · 计算机科学 2026-05-08 Othmane Kabal , Mounira Harzallah , Fabrice Guillet , Hideaki Takeda , Ryutaro Ichise

Medical deep learning models depend heavily on domain-specific knowledge to perform well on knowledge-intensive clinical tasks. Prior work has primarily leveraged unimodal knowledge graphs, such as the Unified Medical Language System…

人工智能 · 计算机科学 2025-05-26 Xiaochen Wang , Yuan Zhong , Lingwei Zhang , Lisong Dai , Ting Wang , Fenglong Ma

Two crucial issues for text summarization to generate faithful summaries are to make use of knowledge beyond text and to make use of cross-sentence relations in text. Intuitive ways for the two issues are Knowledge Graph (KG) and Graph…

计算与语言 · 计算机科学 2023-12-07 Jingqiang Chen

Drug-drug interaction (DDI) is a vital information when physicians and pharmacists intend to co-administer two or more drugs. Thus, several DDI databases are constructed to avoid mistakenly combined use. In recent years, automatically…

计算与语言 · 计算机科学 2017-05-19 Zibo Yi , Shasha Li , Jie Yu , Qingbo Wu

How can we estimate the importance of nodes in a knowledge graph (KG)? A KG is a multi-relational graph that has proven valuable for many tasks including question answering and semantic search. In this paper, we present GENI, a method for…

机器学习 · 计算机科学 2019-06-18 Namyong Park , Andrey Kan , Xin Luna Dong , Tong Zhao , Christos Faloutsos

The rapid expansion of publicly-available medical data presents a challenge for clinicians and researchers alike, increasing the gap between the volume of scientific literature and its applications. The steady growth of studies and findings…

人工智能 · 计算机科学 2025-08-06 Taine J. Elliott , Stephen P. Levitt , Ken Nixon , Martin Bekker

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

机器学习 · 计算机科学 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Knowledge graphs are powerful tools for representing and organising complex biomedical data. Several knowledge graph embedding algorithms have been proposed to learn from and complete knowledge graphs. However, a recent study demonstrates…

Knowledge graphs (KGs) store highly heterogeneous information about the world in the structure of a graph, and are useful for tasks such as question answering and reasoning. However, they often contain errors and are missing information.…

人工智能 · 计算机科学 2020-03-24 Caleb Belth , Xinyi Zheng , Jilles Vreeken , Danai Koutra

Drug-drug interaction (DDI) prediction is critical for treatment safety. While large language models (LLMs) show promise in pharmaceutical tasks, their effectiveness in DDI prediction remains challenging. Inspired by the well-established…

人工智能 · 计算机科学 2025-05-30 Guangyi Liu , Yongqi Zhang , Xunyuan Liu , Quanming Yao