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Graphs are widely used as a natural framework that captures interactions between individual elements represented as nodes in a graph. In medical applications, specifically, nodes can represent individuals within a potentially large…

Deep neural networks have become the gold-standard approach for the automated segmentation of 3D medical images. Their full acceptance by clinicians remains however hampered by the lack of intelligible uncertainty assessment of the provided…

图像与视频处理 · 电气工程与系统科学 2022-09-23 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

神经元与认知 · 定量生物学 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

INTRODUCTION: Alzheimer's disease (AD) is genetically complex, complicating robust classification from genomic data. METHODS: We developed a transformer-based ensemble model (TrUE-Net) using Monte Carlo Dropout for uncertainty estimation in…

基因组学 · 定量生物学 2025-06-03 Taeho Jo , Eun Hye Lee , Alzheimer's Disease Sequencing Project

Deep neural networks are increasingly being used for the analysis of medical images. However, most works neglect the uncertainty in the model's prediction. We propose an uncertainty-aware deep kernel learning model which permits the…

机器学习 · 计算机科学 2021-06-11 Zhiliang Wu , Yinchong Yang , Jindong Gu , Volker Tresp

While graph convolution based methods have become the de-facto standard for graph representation learning, their applications to disease prediction tasks remain quite limited, particularly in the classification of neurodevelopmental and…

计算机视觉与模式识别 · 计算机科学 2023-11-17 Ibrahim Salim , A. Ben Hamza

Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the…

机器学习 · 计算机科学 2018-12-27 Anees Kazi , S. Arvind krishna , Shayan Shekarforoush , Karsten Kortuem , Shadi Albarqouni , Nassir Navab

Exploiting the wealth of imaging and non-imaging information for disease prediction tasks requires models capable of representing, at the same time, individual features as well as data associations between subjects from potentially large…

Recently, Graph Convolutional Networks (GCNs) have proven to be a powerful mean for Computer Aided Diagnosis (CADx). This approach requires building a population graph to aggregate structural information, where the graph adjacency matrix…

人工智能 · 计算机科学 2021-06-17 Hao Chen , Fuzhen Zhuang , Li Xiao , Ling Ma , Haiyan Liu , Ruifang Zhang , Huiqin Jiang , Qing He

Using predictive models to identify patterns that can act as biomarkers for different neuropathoglogical conditions is becoming highly prevalent. In this paper, we consider the problem of Autism Spectrum Disorder (ASD) classification where…

机器学习 · 统计学 2018-10-31 Rushil Anirudh , Jayaraman J. Thiagarajan

With the increasing number of patients diagnosed with Alzheimer's Disease, prognosis models have the potential to aid in early disease detection. However, current approaches raise dependability concerns as they do not account for…

神经元与认知 · 定量生物学 2024-08-28 Wael Mobeirek , Shirley Mao

Brain age estimation is clinically important as it can provide valuable information in the context of neurodegenerative diseases such as Alzheimer's. Population graphs, which include multimodal imaging information of the subjects along with…

Deep Neural Networks - especially Convolutional Neural Network (ConvNet) has become the state-of-the-art for image classification, pattern recognition and various computer vision tasks. ConvNet has a huge potential in medical domain for…

计算机视觉与模式识别 · 计算机科学 2020-09-11 Md Motiur Rahman Sagar , Martin Dyrba

Semi-supervised learning has made significant strides in the medical domain since it alleviates the heavy burden of collecting abundant pixel-wise annotated data for semantic segmentation tasks. Existing semi-supervised approaches enhance…

计算机视觉与模式识别 · 计算机科学 2021-12-03 Xu Zheng , Chong Fu , Haoyu Xie , Jialei Chen , Xingwei Wang , Chiu-Wing Sham

Graph-based neural network models are gaining traction in the field of representation learning due to their ability to uncover latent topological relationships between entities that are otherwise challenging to identify. These models have…

图像与视频处理 · 电气工程与系统科学 2023-07-25 Aryan Singh , Pepijn Van de Ven , Ciarán Eising , Patrick Denny

Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the…

机器学习 · 计算机科学 2022-04-29 Houliang Zhou , Lifang He , Yu Zhang , Li Shen , Brian Chen

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that poses significant diagnostic challenges due to its complex etiology. Graph Convolutional Networks (GCNs) have shown promise in modeling brain connectivity for AD…

计算机视觉与模式识别 · 计算机科学 2025-04-02 Tianqi Ding , Dawei Xiang , Keith E Schubert , Liang Dong

Undirected graphical models are powerful tools for uncovering complex relationships among high-dimensional variables. This paper aims to fully recover the structure of an undirected graphical model when the data naturally take matrix form,…

统计方法学 · 统计学 2025-08-08 Minsub Shin , Johan Lim , Seongoh Park

Various Graph Neural Networks (GNNs) have been successful in analyzing data in non-Euclidean spaces, however, they have limitations such as oversmoothing, i.e., information becomes excessively averaged as the number of hidden layers…

机器学习 · 计算机科学 2024-01-23 Jaeyoon Sim , Sooyeon Jeon , InJun Choi , Guorong Wu , Won Hwa Kim
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