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Diversity indices are useful single-number metrics for characterizing a complex distribution of a set of attributes across a population of interest. The utility of these different metrics or sets of metrics depend on the context and…

种群与进化 · 定量生物学 2020-03-06 Song Xu , Lucas Böttcher , Tom Chou

Modern statisticians are often presented with hundreds or thousands of hypothesis testing problems to evaluate at the same time, generated from new scientific technologies such as microarrays, medical and satellite imaging devices, or flow…

应用统计 · 统计学 2008-12-18 Bradley Efron

Although a vast body of literature relates to image segmentation methods that use deep neural networks (DNNs), less attention has been paid to assessing the statistical reliability of segmentation results. In this study, we interpret the…

机器学习 · 统计学 2022-12-15 Vo Nguyen Le Duy , Shogo Iwazaki , Ichiro Takeuchi

The paper proposes new second-order accuracy metrics for scoring or rating models, which show the target preference of the model, it is better to diagnose good objects or better to diagnose bad ones for a constant generally accepted…

风险管理 · 定量金融 2023-01-19 M. V. Pomazanov

This work is motivated by learning the individualized minimal clinically important difference, a vital concept to assess clinical importance in various biomedical studies. We formulate the scientific question into a high-dimensional…

统计方法学 · 统计学 2023-03-28 Huijie Feng , Jingyi Duan , Yang Ning , Jiwei Zhao

Multi-label text classification (MLTC) tasks in the medical domain often face the long-tail label distribution problem. Prior works have explored hierarchical label structures to find relevant information for few-shot classes, but mostly…

计算与语言 · 计算机科学 2024-06-21 Xueren Ge , Satpathy Abhishek , Ronald Dean Williams , John A. Stankovic , Homa Alemzadeh

Multiple testing problems arise naturally in scientific studies because of the need to capture or convey more information with more variables. The literature is enormous, but the emphasis is primarily methodological, providing numerous…

其他统计学 · 统计学 2020-10-07 Yudi Pawitan , Arvid Sjölander

Gathering observational data for medical decision-making often involves uncertainties arising from both type I (false positive)and type II (false negative) errors. In this work, we develop a statistical model to study how medical…

应用统计 · 统计学 2025-10-21 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

Automated classification methods for disease diagnosis are currently in the limelight, especially for imaging data. Classification does not fully meet a clinician's needs, however: in order to combine the results of multiple tests and…

定量方法 · 定量生物学 2018-05-07 PierGianLuca Porta Mana , Claudia Bachmann , Abigail Morrison

Learning to disentangle and represent factors of variation in data is an important problem in AI. While many advances have been made to learn these representations, it is still unclear how to quantify disentanglement. While several metrics…

机器学习 · 计算机科学 2022-05-10 Marc-André Carbonneau , Julian Zaidi , Jonathan Boilard , Ghyslain Gagnon

Estimation of division and death rates of lymphocytes in different conditions is vital for quantitative understanding of the immune system. Deuterium, in the form of deuterated glucose or heavy water, can be used to measure rates of…

种群与进化 · 定量生物学 2015-05-13 Vitaly V. Ganusov , Jose Borghans , Rob De Boer

In the group testing problem the aim is to identify a small set of $k\sim n^\theta$ infected individuals out of a population size $n$, $0<\theta<1$. We avail ourselves of a test procedure capable of testing groups of individuals, with the…

离散数学 · 计算机科学 2021-05-14 Amin Coja-Oghlan , Oliver Gebhard , Max Hahn-Klimroth , Philipp Loick

The use of group testing to locate all instances of disease in a large population of blood samples was first considered seventy years ago. Since then, several methods have been used to approximate the minimum expected number of tests. The…

应用统计 · 统计学 2015-03-24 Seth Zimmerman

Deep Neural Networks (DNNs), with its promising performance, are being increasingly used in safety critical applications such as autonomous driving, cancer detection, and secure authentication. With growing importance in deep learning,…

机器学习 · 计算机科学 2019-11-19 Senthil Mani , Anush Sankaran , Srikanth Tamilselvam , Akshay Sethi

Deep learning methods have proved highly effective for classification and image recognition problems. In this paper, we ask whether this success can be transferred to hypothesis testing: if a neural network can distinguish, for example, an…

机器学习 · 统计学 2026-04-30 Gery Geenens , Pierre Lafaye de Micheaux , Ivan Muyun Zou

Chronic pain is a global health challenge affecting millions of individuals, making it essential for physicians to have reliable and objective methods to measure the functional impact of clinical treatments. Traditionally used methods, like…

机器学习 · 计算机科学 2026-03-23 Yuanheng Mao , Lillian Yang , Stephen Yang , Ethan Shao , Zihan Li

Binary classification is a task that involves the classification of data into one of two distinct classes. It is widely utilized in various fields. However, conventional classifiers tend to make overconfident predictions for data that…

机器学习 · 计算机科学 2025-03-13 Shoma Yokura , Akihisa Ichiki

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

应用统计 · 统计学 2012-07-02 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

Sampling algorithms, hypergraph degree sequences, and polytopes play a crucial role in statistical analysis of network data. This article offers a brief overview of open problems in this area of discrete mathematics from the point of view…

离散数学 · 计算机科学 2016-01-11 Sonja Petrović

Distribution shifts remain a fundamental problem for the safe application of machine learning systems. If undetected, they may impact the real-world performance of such systems or will at least render original performance claims invalid. In…

机器学习 · 计算机科学 2023-03-10 Lisa M. Koch , Christian M. Schürch , Christian F. Baumgartner , Arthur Gretton , Philipp Berens