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Cell boundary information is crucial for analyzing cell behaviors from time-lapse microscopy videos. Existing supervised cell segmentation tools, such as ImageJ, require tuning various parameters and rely on restrictive assumptions about…

应用统计 · 统计学 2026-01-27 Laura Baracaldo , Blythe King , Haoran Yan , Yizi Lin , Nina Miolane , Mengyang Gu

Determining the spectral density of a molecular system immersed in a proteomic scaffold and in contact to a solvent is a fundamental challenge in the coarse-grained description of, e.g., electron and energy transfer dynamics. Once the…

量子物理 · 物理学 2014-11-04 Leonardo A. Pachon , Paul Brumer

Optical imaging through complex media, such as biological tissues or fog, is challenging due to light scattering. In the multiple scattering regime, wavefront shaping provides an effective method to retrieve information; it relies on…

光学 · 物理学 2022-06-02 Alexandra d'Arco , Fei Xia , Antoine Boniface , Jonathan Dong , Sylvain Gigan

We present an intelligent programmable computational meta-imager that tailors its sequence of coherent scene illuminations not only to a specific information-extraction task (e.g., object recognition) but also adapts to different types and…

信号处理 · 电气工程与系统科学 2022-12-13 Chenqi Qian , Philipp del Hougne

Gaussian processes (GPs) are a good choice for function approximation as they are flexible, robust to over-fitting, and provide well-calibrated predictive uncertainty. Deep Gaussian processes (DGPs) are multi-layer generalisations of GPs,…

机器学习 · 统计学 2017-11-15 Hugh Salimbeni , Marc Deisenroth

A multi-imaging strategy is proposed and experimentally tested to improve the accuracy of photon counting with an electron multiplying charge-coupled device (EMCCD), by taking into account the random nature of its on-chip gain and the…

天体物理学 · 物理学 2009-11-13 Eric Lantz , Jean Luc Blanchet , Luca Furfaro , Fabrice Devaux

Parameter retrieval and model inversion are key problems in remote sensing and Earth observation. Currently, different approximations exist: a direct, yet costly, inversion of radiative transfer models (RTMs); the statistical inversion with…

信号处理 · 电气工程与系统科学 2021-04-22 Daniel Heestermans Svendsen , Pablo Morales-Alvarez , Ana Belen Ruescas , Rafael Molina , Gustau Camps-Valls

Accurate histopathologic interpretation is key for clinical decision-making; however, current deep learning models for digital pathology are often overconfident and poorly calibrated in out-of-distribution (OOD) settings, which limit trust…

计算机视觉与模式识别 · 计算机科学 2026-04-15 Uma Meleti , Jeffrey J. Nirschl

The charge carrier drift mobility in disordered semiconductors is commonly graphically extracted from time-of-flight (ToF) photocurrent transients yielding a single transit time. However, the term transit time is ambiguously defined and…

无序系统与神经网络 · 物理学 2014-05-23 Jens Lorrmann , Manuel Ruf , David Vocke , Vladimir Dyakonov , Carsten Deibel

We present a scalable Gaussian process model for identifying and characterizing smooth multidimensional changepoints, and automatically learning changes in expressive covariance structure. We use Random Kitchen Sink features to flexibly…

Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…

Quantum machine learning algorithms have very recently attracted significant attention in photonic platforms. In particular, reconfigurable integrated photonic circuits offer a promising route, thanks to the possibility of implementing…

Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal. Recent studies have shown that cells can extract multi-dimensional information from…

生物物理 · 物理学 2018-02-14 Yoshihiko Hasegawa

In nanopore technology, the development of multiplexed detection and release platforms with high spatial and temporal resolution remains a significant challenge due to the difficulty in distinguishing signals originating from different…

应用物理 · 物理学 2025-10-16 Ali Douaki , Shukun Weng , Silvia Dante , Nako Nakatsuka , Makusu Tsutsui , Roman Krahne , Denis Garoli

Phase-contrast microscopy converts the optical phase introduced by transparent, unlabeled specimens into modulation in the intensity image. Modern phase imaging techniques are capable of quantifying phase shift at each point in the field of…

Photodissociation is the dominant removal process of molecules in any region exposed to intense ultraviolet (UV) radiation. This includes diffuse and translucent interstellar clouds, dense photon-dominated regions, high velocity shocks, the…

天体物理仪器与方法 · 物理学 2015-02-10 Ewine F. van Dishoeck , Ruud Visser

We report a theoretical study of clusters of evanescently-coupled 2D whispering-gallery (WG) mode optical micro-cavities (termed "photonic molecules") as chemosensing and biosensing platforms. Photonic molecules (PMs) supporting modes with…

光学 · 物理学 2009-11-11 Svetlana V. Boriskina

A one-dimensional nano-metric-thin cell (NC) filled with potassium metal has been built and used to study optical atomic transitions in external magnetic fields. These studies benefit from the remarkable features of the NC allowing one to…

原子物理 · 物理学 2015-05-20 A. Sargsyan , A. Tonoyan , G. Hakhumyan , C. Leroy , Y. Pashayan-Leroy , D. Sarkisyan

Gaussian processes allow for flexible specification of prior assumptions of unknown dynamics in state space models. We present a procedure for efficient Bayesian learning in Gaussian process state space models, where the representation is…

统计计算 · 统计学 2016-04-18 Andreas Svensson , Arno Solin , Simo Särkkä , Thomas B. Schön

Integration is currently the only feasible route towards scalable photonic quantum processing devices that are sufficiently complex to be genuinely useful in computing, metrology, and simulation. Embedded on-chip detection will be critical…

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