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Various approaches to gene selection for cancer classification based on microarray data can be found in the literature and they may be grouped into two categories: univariate methods and multivariate methods. Univariate methods look at each…

定量方法 · 定量生物学 2015-06-18 Min Xu , Rudy Setiono

According to the National Cancer Institute, there were 9.5 million cancer-related deaths in 2018. A challenge in improving treatment is resistance in genetically unstable cells. The purpose of this study is to evaluate unsupervised machine…

基因组学 · 定量生物学 2021-08-12 Anastasia Dunca , Frederick R. Adler

Cancer is a heterogeneous disease with diverse molecular etiologies and outcomes. The Cancer Genome Atlas (TCGA) has released a large compendium of over 10,000 tumors with RNA-seq gene expression measurements. Gene expression captures the…

基因组学 · 定量生物学 2017-11-15 Gregory P. Way , Casey S. Greene

Large amounts of unlabelled data are commonplace for many applications in computational pathology, whereas labelled data is often expensive, both in time and cost, to acquire. We investigate the performance of unsupervised and supervised…

计算机视觉与模式识别 · 计算机科学 2019-07-27 Koen Dercksen , Wouter Bulten , Geert Litjens

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

计算机视觉与模式识别 · 计算机科学 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

We propose an unsupervised method using self-clustering convolutional adversarial autoencoders to classify prostate tissue as tumor or non-tumor without any labeled training data. The clustering method is integrated into the training of the…

计算机视觉与模式识别 · 计算机科学 2018-04-20 Wouter Bulten , Geert Litjens

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several…

图像与视频处理 · 电气工程与系统科学 2023-10-13 Vasileios E. Papageorgiou , Pantelis Dogoulis , Dimitrios-Panagiotis Papageorgiou

The presence of tertiary lymphoid structures (TLSs) on pancreatic pathological images is an important prognostic indicator of pancreatic tumors. Therefore, TLSs detection on pancreatic pathological images plays a crucial role in diagnosis…

图像与视频处理 · 电气工程与系统科学 2023-07-28 Bingxue Wang , Liwen Zou , Jun Chen , Yingying Cao , Zhenghua Cai , Yudong Qiu , Liang Mao , Zhongqiu Wang , Jingya Chen , Luying Gui , Xiaoping Yang

Automated brain tumor segmentation based on deep learning (DL) has achieved promising performance. However, it generally relies on annotated images for model training, which is not always feasible in clinical settings. Therefore, the…

计算机视觉与模式识别 · 计算机科学 2023-04-05 Xinru Zhang , Ni Ou , Chenghao Liu , Zhizheng Zhuo , Yaou Liu , Chuyang Ye

Image classification is widely used to build predictive models for breast cancer diagnosis. Most existing approaches overwhelmingly rely on deep convolutional networks to build such diagnosis pipelines. These model architectures, although…

图像与视频处理 · 电气工程与系统科学 2022-01-20 Alireza Rezazadeh , Yasamin Jafarian , Ali Kord

Supervised matrix factorization (SMF) is a classical machine learning method that simultaneously seeks feature extraction and classification tasks, which are not necessarily a priori aligned objectives. Our goal is to use SMF to learn…

机器学习 · 统计学 2023-11-21 Joowon Lee , Hanbaek Lyu , Weixin Yao

The objectives of this "perspective" paper are to review some recent advances in sparse feature selection for regression and classification, as well as compressed sensing, and to discuss how these might be used to develop tools to advance…

定量方法 · 定量生物学 2015-06-18 Mathukumalli Vidyasagar

Accurately identifying cancer samples is crucial for precise diagnosis and effective patient treatment. Traditional methods falter with high-dimensional and high feature-to-sample count ratios, which are critical for classifying cancer…

机器学习 · 计算机科学 2025-01-14 Tareque Mohmud Chowdhury , Farzana Tabassum , Sabrina Islam , Abu Raihan Mostofa Kamal

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

图像与视频处理 · 电气工程与系统科学 2022-02-22 Wessam M. Salama , Ahmed Shokry

Quantum machine learning offers a promising new paradigm for computational biology by leveraging quantum mechanical principles to enhance cancer classification, biomarker discovery, and bioinformatics diagnostics. In this study, we apply…

基因组学 · 定量生物学 2026-04-22 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Humaira Gowher , Sabre Kais

Machine learning methods are used to discover complex nonlinear relationships in biological and medical data. However, sophisticated learning models are computationally unfeasible for data with millions of features. Here we introduce the…

One of the most challenges in medical imaging is the lack of data and annotated data. It is proven that classical segmentation methods such as U-NET are useful but still limited due to the lack of annotated data. Using a weakly supervised…

图像与视频处理 · 电气工程与系统科学 2020-03-20 Amine Amyar , Romain Modzelewski , Pierre Vera , Vincent Morard , Su Ruan

Feature selection is an important and challenging task in high dimensional clustering. For example, in genomics, there may only be a small number of genes that are differentially expressed, which are informative to the overall clustering…

统计方法学 · 统计学 2019-10-07 Xiangrui Zeng , Hongyu Zheng

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

计算机视觉与模式识别 · 计算机科学 2018-07-25 Eduardo Pinho , Carlos Costa

Training machine learning models to segment tumors and other anomalies in medical images is an important step for developing diagnostic tools but generally requires manually annotated ground truth segmentations, which necessitates…

计算机视觉与模式识别 · 计算机科学 2024-01-24 Jay J. Yoo , Khashayar Namdar , Farzad Khalvati