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As the lateral resolution of FFOCT with spatially incoherent illumination has been shown to be insensitive to aberrations, we demonstrate high resolution en face full-field OCT (FFOCT) retinal imaging without wavefront correction in the…

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

图像与视频处理 · 电气工程与系统科学 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

We propose a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features like retinal…

Adaptive optics in combination with multi-photon techniques is a powerful approach to image deep into a specimen. Remarkably, virtually all adaptive optics schemes today rely on wavefront modulators which are reflective, diffractive, or…

Adaptive optics (AO) is a powerful image correction technique with proven benefits for many life-science microscopy methods. However, the complexity of adding a reflective wavefront modulator and a wavefront sensor into already complicated…

光学 · 物理学 2020-03-26 Pouya Rajaeipour , Alex Dorn , Kaustubh Banerjee , Hans Zappe , Çağlar Ataman

Future large space telescopes will be equipped with adaptive optics (AO) to overcome wavefront aberrations and achieve high contrast for imaging faint astronomical objects, such as earth-like exoplanets and debris disks. In contrast to AO…

天体物理仪器与方法 · 物理学 2020-01-07 He Sun , N. Jeremy Kasdin , Robert Vanderbei

High-resolution tissue imaging is often compromised by sample-induced optical aberrations that degrade resolution and contrast. While wavefront sensor-based adaptive optics (AO) can measure these aberrations, such hardware solutions are…

Imaging through complex scattering media is severely limited by aberrations and scattering which obscure images and reduce resolution. Confocal and temporal gatings partly filter out multiple scattering but are severely degraded by…

光学 · 物理学 2026-05-18 Yiwen Zhang , Minh Dinh , Zeyu Wang , Tianhao Zhang , Tianhang Chen , Chia Wei Hsu

Adaptive optical correction is an efficient technique to obtain high-resolution images of the retinal surface. A main limitation of adaptive optical correction, however, is the small size of the corrected image. For medical purposes it is…

光学 · 物理学 2015-03-27 Aglae Kellerer

Astronomical telescopes suffer from a tradeoff between field of view (FoV) and image resolution: increasing the FoV leads to an optical field that is under-sampled by the science camera. This work presents a novel computational imaging…

天体物理仪器与方法 · 物理学 2025-08-07 Robin Swanson , Esther Y. H. Lin , Masen Lamb , Suresh Sivanandam , Kiriakos N. Kutulakos

The pyramid wavefront sensor (P-WFS) has replaced the Shack-Hartmann (SH-) WFS as sensor of choice for high performance adaptive optics (AO) systems in astronomy because of its flexibility in pupil sampling, its dynamic range, and its…

Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…

图像与视频处理 · 电气工程与系统科学 2022-10-26 Botond Fazekas , Guilherme Aresta , Dmitrii Lachinov , Sophie Riedl , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Optical Coherence Tomography(OCT) is a non-invasive technique capturing cross-sectional area of the retina in micro-meter resolutions. It has been widely used as a auxiliary imaging reference to detect eye-related pathology and predict…

图像与视频处理 · 电气工程与系统科学 2022-09-01 Shuo Chen , Da Ma , Sieun Lee , Timothy T. L. Yu , Gavin Xu , Donghuan Lu , Karteek Popuri , Myeong Jin Ju , Marinko V. Sarunic , Mirza Faisal Beg

Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, offering distinct advantages and limitations. In vivo OCT offers rapid, non-invasive imaging but can suffer from clarity issues and motion artifacts,…

图像与视频处理 · 电气工程与系统科学 2024-12-18 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim

Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage…

This work introduces the first closed-loop adaptive optics (AO) system capable of optically correcting aberrations in real-time without a guidestar or a wavefront sensor. Nearly 40 years ago, Cederquist et al. demonstrated that asymmetric…

图像与视频处理 · 电气工程与系统科学 2026-05-14 Weiyun Jiang , Haiyun Guo , Christopher A. Metzler , Ashok Veeraraghavan

A resolution enhancement technique for optical coherence tomography (OCT), based on Generative Adversarial Networks (GANs), was developed and investigated. GANs have been previously used for resolution enhancement of photography and optical…

图像与视频处理 · 电气工程与系统科学 2021-01-19 Kaicheng Liang , Xinyu Liu , Si Chen , Jun Xie , Wei Qing Lee , Linbo Liu , Hwee Kuan Lee

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

人机交互 · 计算机科学 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie
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