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We present a straightforward method for measuring the fluids' relative viscosity via a simple graphical analysis of the normalised position autocorrelation function of an optically trapped bead, without the need of embarking on laborious…

Optical tweezers are highly versatile laser traps for neutral microparticles, with fundamental applications in physics and in single molecule cell biology. Force measurements are performed by converting the stiffness response to…

光学 · 物理学 2014-06-30 R S Dutra , N B Viana , P A Maia Neto , H M Nussenzveig

In the last two decades, non-equilibrium spectroscopies have evolved from avant-garde studies to crucial tools for expanding our understanding of the physics of strongly correlated materials. The possibility of obtaining simultaneously…

Calibration of optically trapped particles in-vivo has been complicated given the frequency dependence and spatial inhomogeneity of the cytoplasmic viscosity, and the requirement of accurate knowledge of the medium refractive index.…

生物物理 · 物理学 2019-09-25 Rahul Vaippully , Vaibavi Ramanujan , Saumendra Bajpai , Basudev Roy

Accessing the ballistic regime of single particles in liquids remains an experimental challenge that shrouds our understanding of the particle-liquid interactions on exceedingly short time scales. We demonstrate the ballistic measurements…

Optical tweezers (OT) have become an essential technique in several fields of physics, chemistry, and biology as precise micromanipulation tools and microscopic force transducers. Quantitative measurements require the accurate calibration…

It has been argued [Tassieri, \textit{Soft Matter}, 2015, \textbf{11}, 5792] that linear microrheology with optical tweezers (MOT) of living systems ``\textit{is not an option}'', because of the wide gap between the observation time…

Many wormlike micellar systems exhibit appreciable shear thinning due to shear induced alignment. As the micelles get aligned introducing directionality in the system, the viscoelastic properties are no longer expected to be isotropic. An…

软凝聚态物质 · 物理学 2011-05-09 Manas Khan , A. K. Sood

Two-point microrheology measurements from widely separated colloidal particles approach the bulk viscosity of the host medium more reliably than corresponding single point measurements. In addition, active microrheology offers the advantage…

应用物理 · 物理学 2018-04-25 Shuvojit Paul , Randhir Kumar , Ayan Banerjee

Entropy is one of the key thermodynamic variables reflecting changes in the state of matter. Unlike other thermodynamic variables, it is well-defined also for nonequilibrium steady states through its relation to information. Applying this…

统计力学 · 物理学 2026-04-15 Haim Diamant , Gil Ariel

Many measurements on soft condensed matter (e.g., biological and materials) systems track low-dimensional observables projected from the full system phase space as a function of time. Examples are dynamic structure factors, spectroscopic…

统计力学 · 物理学 2021-02-03 Alessio Lapolla , Jeremy C. Smith , Aljaž Godec

Manipulating particles, such as cells and tissues, in a flowing liquid environment is crucial for life science research. Traditional contactless tweezers, although widely used for single-cell manipulation, face several challenges. These…

流体动力学 · 物理学 2025-01-07 Yuhong Zhou , Fubao Yang , Jinrong Liu , Gaole Dai , Zixin Li , Xuzhi Zhou , Peng Jin , Jiping Huang

Optical tweezers are powerful tools based on focused laser beams. They are able to trap, manipulate and investigate a wide range of microscopic and nanoscopic particles in different media, such as liquids, air, and vacuum. Key applications…

Viscosity measurement is essential for process monitoring and autonomous laboratory operation, yet conventional viscometers remain invasive and require controlled laboratory environments that differ substantially from real process…

计算机视觉与模式识别 · 计算机科学 2025-12-03 Jongwon Sohn , Juhyeon Moon , Hyunjoon Jung , Jaewook Nam

Viscosity is a key property of cell membranes that controls mobility of embedded proteins and membrane remodeling. Measuring it is challenging because existing approaches involve complex experimental designs and/or models, and the…

软凝聚态物质 · 物理学 2023-07-19 Hammad A. Faizi , Rumiana Dimova , Petia M. Vlahovska

Subsystem readout during a quantum process, or mid-circuit measurement, is crucial for error correction in quantum computation, simulation, and metrology. Ideal mid-circuit measurement should be faster than the decoherence of the system,…

Optically levitated dielectric nanoparticles have become valuable tools for precision sensing and quantum optomechanical experiments. To predict the dynamic properties of a particle trapped in an optical tweezer with high fidelity, a tool…

光学 · 物理学 2024-11-20 Moosung Lee , Tobias Hanke , Sara Launer , Sungkun Hong

Optical tweezers find applications in various fields, ranging from biology to physics. One of the fundamental steps necessary to perform quantitative measurements using trapped particles is the calibration of the tweezer's spring constant.…

量子物理 · 物理学 2020-06-05 Bruno Melo , Felipe Almeida , Guilherme Temporão , Thiago Guerreiro

Optical tweezers are a technique in which microscopic-sized particles, including living cells and bacteria, can be non-intrusively trapped with high accuracy solely using focused light. The technique has therefore become a powerful tool in…

生物物理 · 物理学 2015-03-04 Magnus Andersson

Photoinduced non-thermal phase transitions are new paradigms of exotic non-equilibrium physics of strongly correlated materials. An ultrashort optical pulse can drive the system to a new order through complex microscopic interactions that…

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