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Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

计算机视觉与模式识别 · 计算机科学 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Background: Accurate deformable image registration (DIR) is required for contour propagation and dose accumulation in MR-guided adaptive radiotherapy (MRgART). This study trained and evaluated a deep learning DIR method for domain invariant…

In this paper, Kernel PCA is reinterpreted as the solution to a convex optimization problem. Actually, there is a constrained convex problem for each principal component, so that the constraints guarantee that the principal component is…

机器学习 · 计算机科学 2017-10-25 Carlos M. Alaíz , Michaël Fanuel , Johan A. K. Suykens

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

图像与视频处理 · 电气工程与系统科学 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Thanks to advancements in diagnosis and treatment, prostate cancer patients have high long-term survival rates. Currently, an important goal is to preserve quality-of-life during and after treatment. The relationship between the radiation a…

定量方法 · 定量生物学 2026-05-12 Zhijian Yang , Daniel Olszewski , Chujun He , Giulia Pintea , Jun Lian , Tom Chou , Ronald Chen , Blerta Shtylla

We hypothesize that probabilistic voxel-level classification of anatomy and malignancy in prostate MRI, although typically posed as near-identical segmentation tasks via U-Nets, require different loss functions for optimal performance due…

图像与视频处理 · 电气工程与系统科学 2021-10-26 Anindo Saha , Joeran Bosma , Jasper Linmans , Matin Hosseinzadeh , Henkjan Huisman

Accurate molecular subtype classification is essential for personalized breast cancer treatment, yet conventional immunohistochemical analysis relies on invasive biopsies and is prone to sampling bias. Although dynamic contrast-enhanced…

计算机视觉与模式识别 · 计算机科学 2026-01-13 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

定量方法 · 定量生物学 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

The probabilistic classification vector machine (PCVM) synthesizes the advantages of both the support vector machine and the relevant vector machine, delivering a sparse Bayesian solution to classification problems. However, the PCVM is…

机器学习 · 计算机科学 2020-06-30 Shengfei Lyu , Xing Tian , Yang Li , Bingbing Jiang , Huanhuan Chen

Histology-based grade classification is clinically important for many cancer types in stratifying patients distinct treatment groups. In prostate cancer, the Gleason score is a grading system used to measure the aggressiveness of prostate…

计算机视觉与模式识别 · 计算机科学 2019-11-07 Jingwen Wang , Richard J. Chen , Ming Y. Lu , Alexander Baras , Faisal Mahmood

Image registration is useful for quantifying morphological changes in longitudinal MR images from prostate cancer patients. This paper describes a development in improving the learning-based registration algorithms, for this challenging…

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

图像与视频处理 · 电气工程与系统科学 2025-10-29 Ovi Sarkar , Md Shafiuzzaman , Md. Faysal Ahamed , Golam Mahmud , Muhammad E. H. Chowdhury

Principal component analysis (PCA) is an unsupervised method for learning low-dimensional features with orthogonal projections. Multilinear PCA methods extend PCA to deal with multidimensional data (tensors) directly via tensor-to-tensor…

机器学习 · 统计学 2015-05-08 Qiquan Shi , Haiping Lu

Early diagnosis and accurate identification of lesion location and progression in prostate cancer (PCa) are critical for assisting clinicians in formulating effective treatment strategies. However, due to the high semantic homogeneity…

图像与视频处理 · 电气工程与系统科学 2025-07-24 Zhengcheng Lin , Zuobin Ying , Zhenyu Li , Zhenyu Liu , Jian Lu , Weiping Ding

Deep learning has been widely applied in neuroimaging, including predicting brain-phenotype relationships from magnetic resonance imaging (MRI) volumes. MRI data usually requires extensive preprocessing prior to modeling, but variation…

机器学习 · 计算机科学 2023-10-17 Xinhui Li , Alex Fedorov , Mrinal Mathur , Anees Abrol , Gregory Kiar , Sergey Plis , Vince Calhoun

When analysing screening mammograms, radiologists can naturally process information across two ipsilateral views of each breast, namely the cranio-caudal (CC) and mediolateral-oblique (MLO) views. These multiple related images provide…

计算机视觉与模式识别 · 计算机科学 2022-09-22 Yuanhong Chen , Hu Wang , Chong Wang , Yu Tian , Fengbei Liu , Michael Elliott , Davis J. McCarthy , Helen Frazer , Gustavo Carneiro

Radiomics is an exciting new area of texture research for extracting quantitative and morphological characteristics of pathological tissue. However, to date, only single images have been used for texture analysis. We have extended radiomic…

图像与视频处理 · 电气工程与系统科学 2019-06-11 Vishwa S. Parekh , John Laterra , Chetan Bettegowda , Alex E. Bocchieri , Jay J. Pillai , Michael A. Jacobs

We apply deep learning (DL) on Magnetic resonance spectroscopy (MRS) data for the task of brain tumor detection. Medical applications often suffer from data scarcity and corruption by noise. Both of these problems are prominent in our data…

机器学习 · 计算机科学 2021-12-17 Diyuan Lu , Gerhard Kurz , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Effective treatment for rectal cancer relies on accurate lymph node metastasis (LNM) staging. However, radiological criteria based on lymph node (LN) size, shape and texture morphology have limited diagnostic accuracy. In this work, we…

计算机视觉与模式识别 · 计算机科学 2025-07-17 Benjamin Keel , Aaron Quyn , David Jayne , Maryam Mohsin , Samuel D. Relton