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Graph neural networks (GNNs) have led to major breakthroughs in a variety of domains such as drug discovery, social network analysis, and travel time estimation. However, they lack interpretability which hinders human trust and thereby…

机器学习 · 计算机科学 2023-12-05 Jonas Jürß , Lucie Charlotte Magister , Pietro Barbiero , Pietro Liò , Nikola Simidjievski

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

基因组学 · 定量生物学 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

Mammography is a vital screening technique for early revealing and identification of breast cancer in order to assist to decrease mortality rate. Practical applications of mammograms are not limited to breast cancer revealing,…

图像与视频处理 · 电气工程与系统科学 2020-10-08 Aparna Bhale , Manish Joshi

We propose a novel computational framework leveraging hypergraph theory to analyse cancer stem cell markers (CSCMs) across multiple organs. Hypergraphs provide a robust representation of CSCM co-expression patterns, capturing their complex…

生物物理 · 物理学 2025-08-01 David H. Margarit , Gustavo Paccosi , Marcela V. Reale , Lilia M. Romanelli

Causal approaches to post-hoc explainability for black-box prediction models (e.g., deep neural networks trained on image pixel data) have become increasingly popular. However, existing approaches have two important shortcomings: (i) the…

机器学习 · 计算机科学 2025-08-12 Numair Sani , Daniel Malinsky , Ilya Shpitser

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

机器学习 · 计算机科学 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

Control Flow Graphs and Function Call Graphs have become pivotal in providing a detailed understanding of program execution and effectively characterizing the behavior of malware. These graph-based representations, when combined with Graph…

密码学与安全 · 计算机科学 2024-12-06 Hesamodin Mohammadian , Griffin Higgins , Samuel Ansong , Roozbeh Razavi-Far , Ali A. Ghorbani

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

图像与视频处理 · 电气工程与系统科学 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

The Deep learning (DL) models for diagnosing breast cancer from mammographic images often operate as "black boxes", making it difficult for healthcare professionals to trust and understand their decision-making processes. The study presents…

计算机视觉与模式识别 · 计算机科学 2024-04-30 Maryam Ahmed , Tooba Bibi , Rizwan Ahmed Khan , Sidra Nasir

Deep neural networks have shown potential in analyzing digitized hand-drawn signals for early diagnosis of Parkinson's disease. However, the lack of clear interpretability in existing diagnostic methods presents a challenge to clinical…

计算机视觉与模式识别 · 计算机科学 2025-05-08 Xuechao Wang , Sven Nomm , Junqing Huang , Kadri Medijainen , Aaro Toomela , Michael Ruzhansky

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Converting malware into images followed by vision-based deep learning algorithms has shown superior threat detection efficacy compared with classical machine learning algorithms. When malware are visualized as images, visual-based…

密码学与安全 · 计算机科学 2019-05-02 Li Chen , Carter Yagemann , Evan Downing

Neural networks for NLP are becoming increasingly complex and widespread, and there is a growing concern if these models are responsible to use. Explaining models helps to address the safety and ethical concerns and is essential for…

计算与语言 · 计算机科学 2023-11-29 Andreas Madsen , Siva Reddy , Sarath Chandar

While deep learning has achieved great success in many fields, one common criticism about deep learning is its lack of interpretability. In most cases, the hidden units in a deep neural network do not have a clear semantic meaning or…

基因组学 · 定量生物学 2019-06-04 Tianle Ma , Aidong Zhang

Digital mammography is essential to breast cancer detection, and deep learning offers promising tools for faster and more accurate mammogram analysis. In radiology and other high-stakes environments, uninterpretable ("black box") deep…

计算机视觉与模式识别 · 计算机科学 2024-06-11 Julia Yang , Alina Jade Barnett , Jon Donnelly , Satvik Kishore , Jerry Fang , Fides Regina Schwartz , Chaofan Chen , Joseph Y. Lo , Cynthia Rudin

Significant disparities between the features of natural images and those inherent to histopathological images make it challenging to directly apply and transfer pre-trained models from natural images to histopathology tasks. Moreover, the…

计算机视觉与模式识别 · 计算机科学 2024-12-17 Zhenfeng Zhuang , Min Cen , Yanfeng Li , Fangyu Zhou , Lequan Yu , Baptiste Magnier , Liansheng Wang

Instance-level graph neural network explainers have proven beneficial for explaining such networks on histopathology images. However, there has been few methods that provide model explanations, which are common patterns among samples within…

图像与视频处理 · 电气工程与系统科学 2023-04-18 Sina Abdous , Reza Abdollahzadeh , Mohammad Hossein Rohban

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

图像与视频处理 · 电气工程与系统科学 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Advances in data collection in radiation therapy have led to an abundance of opportunities for applying data mining and machine learning techniques to promote new data-driven insights. In light of these advances, supporting collaboration…