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Optical tweezers equipped with position detection allow for application of piconewton-scale forces and high-temporal-resolution measurements of nanometer-scale motion. While typically used for trapping microscopic objects, the optical…

Optical tweezers are a technique in which microscopic-sized particles, including living cells and bacteria, can be non-intrusively trapped with high accuracy solely using focused light. The technique has therefore become a powerful tool in…

生物物理 · 物理学 2015-03-04 Magnus Andersson

Fully internal and motional state controlled and individually manipulable polar molecules are desirable for many quantum science applications leveraging the rich state space and intrinsic interactions of molecules. While prior efforts at…

Optical tweezers exploit light--matter interactions to trap particles ranging from single atoms to micrometer-sized eukaryotic cells. For this reason, optical tweezers are a ubiquitous tool in physics, biology, and nanotechnology. Recently,…

Since the pioneering work of Arthur Ashkin, optical tweezers have become an indispensable tool for contactless manipulation of micro- and nanoparticles. Nowadays optical tweezers are employed in a myriad of applications demonstrating the…

It is common to introduce optical tweezers using either geometric optics for large particles or the Rayleigh approximation for very small particles. These approaches are successful at conveying the key ideas behind optical tweezers in their…

Optical tweezers are powerful tools based on focused laser beams. They are able to trap, manipulate and investigate a wide range of microscopic and nanoscopic particles in different media, such as liquids, air, and vacuum. Key applications…

Computational modelling has made many useful contributions to the field of optical tweezers. One aspect in which it can be applied is the simulation of the dynamics of particles in optical tweezers. This can be useful for systems with many…

Optical tweezers have been widely used for optical manipulation of various particles. At present, there are different type of optical tweezers. Among them, holographic optical tweezers have attracted growing attention as a powerful tools…

光学 · 物理学 2025-02-12 Yida Song , Zhengshu Zhang , Yi Shen , Xionggui Tang

Emulsions are ubiquitous in everyday life and find applications in various industries. Optical tweezers (OTs) have emerged as the preferred method for studying emulsion dynamics. In this review, we first introduce the theory of optical…

Optical tweezers, with their high precision, dynamic control, and non-invasiveness, are increasingly important in scientific research and applications at the micro and nano scales. However, manipulation by optical tweezers is challenged by…

The assembly of arbitrary 3D structures using nano- to micron-scale colloidal building blocks has broad applications in photonics, electronics, and biology. Combining optical tweezers (OT) with two-photon polymerization (TPP) enables 3D…

Optical tweezers constitute pivotal tools in Atomic, Molecular, and Optical(AMO) physics, facilitating precise trapping and manipulation of individual atoms and molecules. This process affords the capability to generate desired geometries…

原子物理 · 物理学 2024-01-11 Yongwoong Lee , Eunmi Chae

Since their invention in 1986 by Arthur Ashkin and colleagues, optical tweezers have become an essential tool in several fields of physics, spectroscopy, biology, nanotechnology, and thermodynamics. In this Tutorial, we provide a primer on…

Biophysical force spectroscopy tools - for example optical tweezers, magnetic tweezers, atomic force microscopy, - have been used to study elastic, mechanical, conformational and dynamic properties of single biological specimens from single…

生物大分子 · 定量生物学 2016-06-09 Zhaokun Zhou , Mark C. Leake

Bacterial biofilms underlie many persistent infections, posing major hurdles in antibiotic treatment. Here, we design and demonstrate tug-of-war optical tweezers that can facilitate assessment of cell-cell adhesion - a key contributing…

光学 · 物理学 2016-05-24 Anna Bezryadina , Daryl Preece , Joseph C. Chen , Zhigang Chen

Optical tweezers are powerful tools for high resolution study of surface properties. Such experiments are traditionally performed by studying the active or the brownian fluctuation of trapped particles in the X, Y, Z direction. Here we find…

光学 · 物理学 2018-11-13 Rahul Vaipully , Dhanush Bhatt , Anand Dev Ranjan , Basudev Roy

Optical tweezers are highly versatile laser traps for neutral microparticles, with fundamental applications in physics and in single molecule cell biology. Force measurements are performed by converting the stiffness response to…

光学 · 物理学 2014-06-30 R S Dutra , N B Viana , P A Maia Neto , H M Nussenzveig

Critical Casimir forces emerge between objects, such as colloidal particles, whenever their surfaces spatially confine the fluctuations of the order parameter of a critical liquid used as a solvent. These forces act at short but…

软凝聚态物质 · 物理学 2020-08-05 Agnese Callegari , Alessandro Magazzù , Andrea Gambassi , Giovanni Volpe

Optical tweezers have found widespread application in many fields, from physics to biology. Here, we explain in detail how optical forces and torques can be described within the geometrical optics approximation and we show that this…

光学 · 物理学 2015-06-18 Agnese Callegari , Mite Mijalkov , A. Burak Gököz , Giovanni Volpe
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