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Electronic medical records (EMRs), particularly in neurology, are inherently heterogeneous, sparse, and noisy, which poses significant challenges for large language models (LLMs) in clinical diagnosis. In such settings, single-agent systems…

人工智能 · 计算机科学 2026-04-30 Shaowei Shen , Xiaohong Yang , Jie Yang , Lianfen Huang , Yongcai Zhang , Yang Zou , Seyyedali Hosseinalipour

We study an EM algorithm for estimating product-term regression models with missing data. The study of such problems in the likelihood tradition has thus far been restricted to an EM algorithm method using full numerical integration.…

统计方法学 · 统计学 2021-11-16 Dale S. Kim

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

机器学习 · 计算机科学 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

Objective: To transform heterogeneous clinical data from electronic health records into clinically meaningful constructed features using data driven method that rely, in part, on temporal relations among data. Materials and Methods: The…

机器学习 · 计算机科学 2017-06-22 Edward Choi , Andy Schuetz , Walter F. Stewart , Jimeng Sun

Unlearning in large language models (LLMs) aims to remove specified data, but its efficacy is typically assessed with task-level metrics like accuracy and perplexity. We show that these metrics can be misleading, as models can appear to…

计算与语言 · 计算机科学 2026-05-19 Xiaoyu Xu , Xiang Yue , Yang Liu , Qingqing Ye , Huadi Zheng , Peizhao Hu , Minxin Du , Haibo Hu

Advancements in data collection techniques and the heterogeneity of data resources can yield high percentages of missing observations on variables, such as block-wise missing data. Under missing-data scenarios, traditional methods such as…

统计方法学 · 统计学 2022-05-17 Wei Lan , Xuerong Chen , Tao Zou , Chih-Ling Tsai

Automatic representation learning of key entities in electronic health record (EHR) data is a critical step for healthcare informatics that turns heterogeneous medical records into structured and actionable information. Here we propose…

机器学习 · 计算机科学 2019-10-08 Tong Wu , Yunlong Wang , Yue Wang , Emily Zhao , Yilian Yuan , Zhi Yang

Medical Decision-Making (MDM) is a complex process requiring substantial domain-specific expertise to effectively synthesize heterogeneous and complicated clinical information. While recent advancements in Large Language Models (LLMs) show…

人工智能 · 计算机科学 2025-08-20 Liuxin Bao , Zhihao Peng , Xiaofei Zhou , Runmin Cong , Jiyong Zhang , Yixuan Yuan

Data-driven method for Structural Health Monitoring (SHM), that mine the hidden structural performance from the correlations among monitored time series data, has received widely concerns recently. However, missing data significantly…

机器学习 · 计算机科学 2023-04-04 Fan Deng , Xiaoming Tao , Pengxiang Wei , Shiyin Wei

Missing data presents a critical challenge in real-world datasets, significantly degrading the performance of machine learning models. While Large Language Models (LLMs) have recently demonstrated remarkable capabilities in tabular data…

机器学习 · 计算机科学 2025-07-14 Hossein Jamali

Latent space models are widely used for analyzing high-dimensional discrete data matrices, such as patient-feature matrices in electronic health records (EHRs), by capturing complex dependence structures through low-dimensional embeddings.…

机器学习 · 计算机科学 2026-02-19 Weijing Tang , Ming Yuan , Zongqi Xia , Tianxi Cai

To accelerate learning process with few samples, meta-learning resorts to prior knowledge from previous tasks. However, the inconsistent task distribution and heterogeneity is hard to be handled through a global sharing model…

机器学习 · 计算机科学 2022-06-22 Geng Li , Boyuan Ren , Hongzhi Wang

Missing values of varying patterns and rates in real-world tabular data pose a significant challenge in developing reliable data-driven models. The most commonly used statistical and machine learning methods for missing value imputation may…

机器学习 · 计算机科学 2025-03-26 Ibna Kowsar , Shourav B. Rabbani , Yina Hou , Manar D. Samad

Clinical decision support using data mining techniques offers more intelligent way to reduce the decision error in the last few years. However, clinical datasets often suffer from high missingness, which adversely impacts the quality of…

机器学习 · 计算机科学 2020-11-20 Xuetong Wu , Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Zobaida Edib , Michelle Peate

The efficacy of Large Vision-Language Models (LVLMs) is critically dependent on the quality of their training data, requiring a precise balance between visual fidelity and instruction-following capability. Existing datasets, however, are…

计算机视觉与模式识别 · 计算机科学 2026-04-23 Zimu Jia , Mingjie Xu , Andrew Estornell , Jiaheng Wei

For many machine learning tasks, the input data lie on a low-dimensional manifold embedded in a high dimensional space and, because of this high-dimensional structure, most algorithms are inefficient. The typical solution is to reduce the…

机器学习 · 计算机科学 2019-03-05 Anna C. Gilbert , Rishi Sonthalia

Electronic Health Records present a valuable modality for driving personalized medicine, where treatment is tailored to fit individual-level differences. For this purpose, many data-driven machine learning and statistical models rely on the…

机器学习 · 计算机科学 2024-12-16 Ghadeer O. Ghosheh , Jin Li , Tingting Zhu

Missing data imputation is a critical challenge in various domains, such as healthcare and finance, where data completeness is vital for accurate analysis. Large language models (LLMs), trained on vast corpora, have shown strong potential…

机器学习 · 计算机科学 2025-08-26 Xinrui He , Yikun Ban , Jiaru Zou , Tianxin Wei , Curtiss B. Cook , Jingrui He

The rapid integration of machine learning methodologies in healthcare has ignited innovative strategies for disease prediction, particularly with the vast repositories of Electronic Health Records (EHR) data. This article delves into the…

机器学习 · 计算机科学 2024-08-07 D. Dhinakaran , S. Edwin Raja , M. Thiyagarajan , J. Jeno Jasmine , P. Raghavan

Time series classification with missing data is a prevalent issue in time series analysis, as temporal data often contain missing values in practical applications. The traditional two-stage approach, which handles imputation and…

机器学习 · 计算机科学 2024-08-13 Pengshuai Yao , Mengna Liu , Xu Cheng , Fan Shi , Huan Li , Xiufeng Liu , Shengyong Chen