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Automated classification methods for disease diagnosis are currently in the limelight, especially for imaging data. Classification does not fully meet a clinician's needs, however: in order to combine the results of multiple tests and…

定量方法 · 定量生物学 2018-05-07 PierGianLuca Porta Mana , Claudia Bachmann , Abigail Morrison

A broad spectrum of data from different modalities are generated in the healthcare domain every day, including scalar data (e.g., clinical measures collected at hospitals), tensor data (e.g., neuroimages analyzed by research institutes),…

机器学习 · 计算机科学 2018-03-28 Bokai Cao

The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases. Here we introduce a new phenotypic database summarizing…

生物物理 · 物理学 2015-05-14 Cesar A. Hidalgo , Nicholas Blumm , Albert-Laszlo Barabasi , Nicholas Christakis

In this paper, we present a comprehensive survey on the pervasive issue of medical misinformation in social networks from the perspective of information technology. The survey aims at providing a systematic review of related research and…

Metadata-the machine-readable descriptions of the data-are increasingly seen as crucial for describing the vast array of biomedical datasets that are currently being deposited in public repositories. While most public repositories have firm…

This paper presents a method for building patient-based networks that we call Precision disease networks, and its uses for predicting medical outcomes. Our methodology consists of building networks, one for each patient or case, that…

定量方法 · 定量生物学 2019-11-01 J. Cabrera , D. Amaratunga , W. Kostis , J Kostis

The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models…

Mining discriminative subgraph patterns from graph data has attracted great interest in recent years. It has a wide variety of applications in disease diagnosis, neuroimaging, etc. Most research on subgraph mining focuses on the graph…

机器学习 · 计算机科学 2016-11-15 Bokai Cao , Xiangnan Kong , Jingyuan Zhang , Philip S. Yu , Ann B. Ragin

The amount of scientific papers published every day is daunting and constantly increasing. Keeping up with literature represents a challenge. If one wants to start exploring new topics it is hard to have a big picture without reading lots…

信息检索 · 计算机科学 2020-11-10 Alberto Calderone

This research is to search for alternatives to the resolution of complex medical diagnosis where human knowledge should be apprehended in a general fashion. Successful application examples show that human diagnostic capabilities are…

神经与进化计算 · 计算机科学 2010-09-28 S. M. Kamruzzaman , Ahmed Ryadh Hasan , Abu Bakar Siddiquee , Md. Ehsanul Hoque Mazumder

Social media may disseminate medical claims that highlight misleading correlations between social identifiers and diseases due to not accounting for structural determinants of health. Our research aims to identify biased medical claims on…

社会与信息网络 · 计算机科学 2023-12-27 Libby Tiderman , Juan Sanchez Mercedes , Fiona Romanoschi , Fabricio Murai

There is a growing proportion of people with several disease conditions ("multimorbidity"), placing increasing demands on healthcare systems. One hypothesis is that clusters of diseases may arise from shared underlying disease processes…

统计方法学 · 统计学 2025-08-15 Anthony J. Webster

Social media's unfettered access has made it an important venue for health discussion and a resource for patients and their loved ones. However, the quality of the information available, as well as the motivations of its posters, has been…

计算机与社会 · 计算机科学 2018-09-10 Amira Ghenai , Yelena Mejova

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many…

计算与语言 · 计算机科学 2021-01-28 Yichao Du , Pengfei Luo , Xudong Hong , Tong Xu , Zhe Zhang , Chao Ren , Yi Zheng , Enhong Chen

We analyzed Medical Subject Headings (MeSH) from 21.6 million research articles indexed by PubMed to map this vast space of entities and their relations, providing insights into the origins and future of biomedical convergence. Detailed…

数字图书馆 · 计算机科学 2023-06-27 Dong Yang , Ioannis Pavlidis , Alexander M. Petersen

Disease-gene association through Genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations.…

定量方法 · 定量生物学 2020-12-21 Sezin Kircali Ata , Min Wu , Yuan Fang , Le Ou-Yang , Chee Keong Kwoh , Xiao-Li Li

Background: Bayesian Networks (BNs) are probabilistic graphical models that leverage Bayes' theorem to portray dependencies and cause-and-effect relationships between variables. These networks have gained prominence in the field of health…

Knowledge base construction is crucial for summarising, understanding and inferring relationships between biomedical entities. However, for many practical applications such as drug discovery, the scarcity of relevant facts (e.g. gene X is…

计算与语言 · 计算机科学 2019-07-04 Julien Fauqueur , Ashok Thillaisundaram , Theodosia Togia

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

神经元与认知 · 定量生物学 2018-11-16 Patrick Schwab , Walter Karlen

The multiple extension problem arises frequently in diagnostic and default inference. That is, we can often use any of a number of sets of defaults or possible hypotheses to explain observations or make Predictions. In default inference,…

人工智能 · 计算机科学 2013-04-11 Eric Neufeld , David L Poole