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Despite the popularity of the false discovery rate (FDR) as an error control metric for large-scale multiple testing, its close Bayesian counterpart the local false discovery rate (lfdr), defined as the posterior probability that a…

统计方法学 · 统计学 2023-09-22 Jake A. Soloff , Daniel Xiang , William Fithian

To find interesting items in genome-wide association studies or next generation sequencing data, a crucial point is to design powerful false discovery rate (FDR) controlling procedures that suitably combine discrete tests (typically…

统计理论 · 数学 2017-09-18 Sebastian Döhler , Guillermo Durand , Etienne Roquain

Random Forest has become one of the most popular tools for feature selection. Its ability to deal with high-dimensional data makes this algorithm especially useful for studies in neuroimaging and bioinformatics. Despite its popularity and…

机器学习 · 计算机科学 2014-10-13 Ender Konukoglu , Melanie Ganz

Modern biomedical research frequently involves testing multiple related hypotheses, while maintaining control over a suitable error rate. In many applications the false discovery rate (FDR), which is the expected proportion of false…

统计方法学 · 统计学 2018-09-27 David S. Robertson , James M. S. Wason

We introduce a synthetic control methodology to study policies with staggered adoption. Many policies, such as the board gender diversity policies, are replicated by other policy setters at different time frames. Our method estimates the…

计量经济学 · 经济学 2025-11-18 Jianfei Cao , Shirley Lu , Hang Wu

Many approaches for multiple testing begin with the assumption that all tests in a given study should be combined into a global false-discovery-rate analysis. But this may be inappropriate for many of today's large-scale screening problems,…

统计方法学 · 统计学 2014-06-10 James G. Scott , Ryan C. Kelly , Matthew A. Smith , Pengcheng Zhou , Robert E. Kass

In large scale multiple testing problems, a two-class empirical Bayes approach can be used to control the false discovery rate (Fdr) for the entire array of hypotheses under study. A sample splitting step is incorporated to modify that…

统计计算 · 统计学 2019-12-13 Paramita Chakraborty , Chong Ma , John Grego , James Lynch

We present a novel necessary and sufficient principle for False Discovery Rate (FDR) control. This e-Partitioning Principle says that a procedure controls FDR if and only if it is a special case of a general e-Partitioning procedure. By…

统计理论 · 数学 2025-09-15 Jelle Goeman , Rianne de Heide , Aldo Solari

Active labor market programs are important instruments used by European employment agencies to help the unemployed find work. Investigating large administrative data on German long-term unemployed persons, we analyze the effectiveness of…

综合经济学 · 经济学 2023-05-30 Daniel Goller , Tamara Harrer , Michael Lechner , Joachim Wolff

Model-X knockoffs is a flexible wrapper method for high-dimensional regression algorithms, which provides guaranteed control of the false discovery rate (FDR). Due to the randomness inherent to the method, different runs of model-X…

统计方法学 · 统计学 2023-09-01 Zhimei Ren , Rina Foygel Barber

The fixed-X knockoff filter is a flexible framework for variable selection with false discovery rate (FDR) control in linear models with arbitrary design matrices (of full column rank) and it allows for finite-sample selective inference via…

统计理论 · 数学 2023-11-28 Mehrdad Pournaderi , Yu Xiang

This paper develops a framework for testing for associations in a possibly high-dimensional linear model where the number of features/variables may far exceed the number of observational units. In this framework, the observations are split…

统计方法学 · 统计学 2018-05-04 Rina Foygel Barber , Emmanuel J. Candes

E-values have gained attention as potential alternatives to p-values as measures of uncertainty, significance and evidence. In brief, e-values are realized by random variables with expectation at most one under the null; examples include…

统计理论 · 数学 2021-12-16 Ruodu Wang , Aaditya Ramdas

We address the problem of providing inference from a Bayesian perspective for parameters selected after viewing the data. We present a Bayesian framework for providing inference for selected parameters, based on the observation that…

统计计算 · 统计学 2015-03-13 Daniel Yekutieli

Multiple testing has been a popular topic in statistical research. Although vast works have been done, controlling the false discoveries remains a challenging task when the corresponding test statistics are dependent. Various methods have…

统计理论 · 数学 2022-07-05 Meng Mei , Tao Yu , Yuan Jiang

Gaussian graphical models emerge in a wide range of fields. They model the statistical relationships between variables as a graph, where an edge between two variables indicates conditional dependence. Unfortunately, well-established…

机器学习 · 统计学 2024-01-19 Taulant Koka , Jasin Machkour , Michael Muma

How to weigh the Benjamini-Hochberg procedure? In the context of multiple hypothesis testing, we propose a new step-wise procedure that controls the false discovery rate (FDR) and we prove it to be more powerful than any weighted…

统计理论 · 数学 2009-07-13 Etienne Roquain , Mark Van De Wiel

We investigate the performance of dynamic portfolios constructed using more than 21,000 technical trading rules on 12 categorical and country-specific markets over the 2004-2015 study period, on rolling forward structures of different…

When selecting from a list of potential candidates, it is important to ensure not only that the selected items are of high quality, but also that they are sufficiently dissimilar so as to both avoid redundancy and to capture a broader range…

统计方法学 · 统计学 2026-02-25 Yash Nair , Ying Jin , James Yang , Emmanuel Candes

Some effort has been undertaken over the last decade to provide conditions for the control of the false discovery rate by the linear step-up procedure (LSU) for testing $n$ hypotheses when test statistics are dependent. In this paper we…

统计理论 · 数学 2007-10-18 Helmut Finner , Thorsten Dickhaus , Markus Roters