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Objectives Lung squamous cell carcinoma (LUSC) often diagnosed as advanced with poor prognosis. The mechanisms of its pathogenesis and prognosis require urgent elucidation. This study was performed to screen potential biomarkers related to…

基因组学 · 定量生物学 2019-11-14 Miaomiao Gao , Weikaixin Kong , Zhuo Huang , Zhengwei Xie

Background: Colorectal adenocarcinoma (CRC) remains a leading cause of cancer-related mortality worldwide, with variable patient outcomes despite treatment advances. Traditional prognostic methods based on clinicopathological variables…

定量方法 · 定量生物学 2025-07-28 Oluwafemi Ogundare

Melanoma is a type of skin cancer developed from melanocytes. It is one of the most lethal types of cancer, accounting for approximately 75% of skin cancer deaths. Late stage melanoma is very difficult to treat, since the cancer cells are…

定量方法 · 定量生物学 2018-11-28 Xue Teng , Fuad Gwadry , Haley McConkey , Scott Ernst , Femida Gwadry-Sridhar

Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated with cancer is partially due to the lack of reliable early detection methods and/or inaccurate diagnostic tools such as certain protein biomarkers.…

生物大分子 · 定量生物学 2021-09-27 Cedric Badowski , Bing He , Lana X Garmire

Gliomas are lethal type of central nervous system tumors with a poor prognosis. Recently, with the advancements in the micro-array technologies thousands of gene expression related data of glioma patients are acquired, leading for salient…

基因组学 · 定量生物学 2020-11-03 Navodini Wijethilake , Dulani Meedeniya , Charith Chitraranjan , Indika Perera

Radiomics has shown a capability for different types of cancers such as glioma to predict the clinical outcome. It can have a non-invasive means of evaluating the immunotherapy response prior to treatment. However, the use of deep…

图像与视频处理 · 电气工程与系统科学 2022-06-07 Ahmad Chaddad , Mingli Zhang , Lama Hassan , Tamim Niazi

Background: Accurate survival prediction in breast cancer is essential for patient stratification and personalized therapy. Integrating gene expression data with clinical factors may enhance prognostic performance and support precision…

Skin cancer is the most common type of cancer. Specifically, melanoma is the cause of 75% of skin cancer deaths, although it is the least common skin cancer. Better detection of melanoma could have a positive impact on millions of people.…

计算机视觉与模式识别 · 计算机科学 2023-02-21 Chengdong Yao

Skin cancer is the most common cancer in the existing world constituting one-third of the cancer cases. Benign skin cancers are not fatal, can be cured with proper medication. But it is not the same as the malignant skin cancers. In the…

图像与视频处理 · 电气工程与系统科学 2022-12-21 Dusa Sai Charan , Hemanth Nadipineni , Subin Sahayam , Umarani Jayaraman

Colorectal cancer is one of the most common and lethal cancers and colorectal cancer liver metastases (CRLM) is the major cause of death in patients with colorectal cancer. Multifocality occurs frequently in CRLM, but is relatively…

计算机视觉与模式识别 · 计算机科学 2021-07-13 Jianan Chen , Helen M. C. Cheung , Laurent Milot , Anne L. Martel

Understanding how deep learning models predict oncology patient risk can provide critical insights into disease progression, support clinical decision-making, and pave the way for trustworthy and data-driven precision medicine. Building on…

计算机视觉与模式识别 · 计算机科学 2024-11-13 Marvin Sextro , Gabriel Dernbach , Kai Standvoss , Simon Schallenberg , Frederick Klauschen , Klaus-Robert Müller , Maximilian Alber , Lukas Ruff

This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…

机器学习 · 计算机科学 2016-11-17 Christopher Roadknight , Durga Suryanarayanan , Uwe Aickelin , John Scholefield , Lindy Durrant

Skin Cancer is one of the most deathful of all the cancers. It is bound to spread to different parts of the body on the off chance that it is not analyzed and treated at the beginning time. It is mostly because of the abnormal growth of…

机器学习 · 计算机科学 2019-12-10 Rishu Garg , Saumil Maheshwari , Anupam Shukla

Immune checkpoint inhibitors (ICIs) have transformed cancer therapy; yet substantial proportion of patients exhibit intrinsic or acquired resistance, making accurate pre-treatment response prediction a critical unmet need.…

The anti-cancer immune response relies on the bindings between T-cell receptors (TCRs) and antigens, which elicits adaptive immunity to eliminate tumor cells. This ability of the immune system to respond to novel various neoantigens arises…

定量方法 · 定量生物学 2025-11-11 Xing Fang , Chenpeng Yu , Shiye Tian , Hui Liu

Head and Neck Squamous Cell Carcinoma (HNSCC) is one of cancer type that is most distressing leading to acute pain, effecting speech and primary survival functions such as swallowing and breathing. The morbidity and mortality of HNSCC…

基因组学 · 定量生物学 2021-05-18 Saurav Mandal , Akshansh Gupta , Waribam Pratibha Chanu

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

计算机视觉与模式识别 · 计算机科学 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

Background Non-small cell lung cancer (NSCLC) is the predominant histological type of lung cancer, accounting for up to 85% of cases. Disease stage is commonly used to determine adjuvant treatment eligibility of NSCLC patients, however, it…

应用统计 · 统计学 2015-08-07 Suyan Tian , Chi Wang , Ming-Wen An

Skin lesions are classified in benign or malignant. Among the malignant, melanoma is a very aggressive cancer and the major cause of deaths. So, early diagnosis of skin cancer is very desired. In the last few years, there is a growing…

The emerging research shows that lncRNA has crucial research value in a series of complex human diseases. Therefore, the accurate identification of lncRNA-disease associations (LDAs) is very important for the warning and treatment of…

机器学习 · 计算机科学 2024-06-06 Wen-Yu Xi , Juan Wang , Yu-Lin Zhang , Jin-Xing Liu , Yin-Lian Gao
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