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This study introduces a data-driven, machine learning-based method to detect suitable control variables and instruments for assessing the causal effect of a treatment on an outcome in observational data. Our approach tests the joint…

计量经济学 · 经济学 2026-05-20 Nicolas Apfel , Julia Hatamyar , Martin Huber , Jannis Kueck

A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be…

机器学习 · 统计学 2016-07-07 Yingfei Wang , Warren Powell

Individualized treatment rules aim to identify if, when, which, and to whom treatment should be applied. A globally aging population, rising healthcare costs, and increased access to patient-level data have created an urgent need for…

统计方法学 · 统计学 2019-01-04 Ying-Qi Zhao , Eric B. Laber , Yang Ning , Sumona Saha , Bruce Sands

A decision maker typically (i) incorporates training data to learn about the relative effectiveness of treatments, and (ii) chooses an implementation mechanism that implies an ``optimal'' predicted outcome distribution according to some…

计量经济学 · 经济学 2025-05-29 Anders Bredahl Kock , David Preinerstorfer

Randomized experimentation (also known as A/B testing or bucket testing) is widely used in the internet industry to measure the metric impact obtained by different treatment variants. A/B tests identify the treatment variant showing the…

统计方法学 · 统计学 2020-12-23 Ye Tu , Kinjal Basu , Cyrus DiCiccio , Romil Bansal , Preetam Nandy , Padmini Jaikumar , Shaunak Chatterjee

Predicting future outcomes is a prevalent application of machine learning in social impact domains. Examples range from predicting student success in education to predicting disease risk in healthcare. Practitioners recognize that the…

机器学习 · 计算机科学 2023-09-11 Lydia T. Liu , Solon Barocas , Jon Kleinberg , Karen Levy

Machine learning is increasingly used to select which individuals receive limited-resource interventions in domains such as human services, education, development, and more. However, it is often not apparent what the right quantity is for…

机器学习 · 计算机科学 2025-03-20 Vibhhu Sharma , Bryan Wilder

Ordering a minimal subset of lab tests for patients in the intensive care unit (ICU) can be challenging. Care teams must balance between ensuring the availability of the right information and reducing the clinical burden and costs…

机器学习 · 计算机科学 2025-04-25 Zongliang Ji , Andre Carlos Kajdacsy-Balla Amaral , Anna Goldenberg , Rahul G. Krishnan

We consider a randomized controlled trial between two groups. The objective is to identify a population with characteristics such that the test therapy is more effective than the control therapy. Such a population is called a subgroup. This…

统计方法学 · 统计学 2021-12-06 Shintaro Yuki , Kensuke Tanioka , Hiroshi Yadohisa

There is a growing literature on finding so-called optimal treatment rules, which are rules by which to assign treatment to individuals based on an individual's characteristics, such that a desired outcome is maximized. A related goal…

应用统计 · 统计学 2021-01-22 Kara E. Rudolph , Ivan Diaz

The concept of personalised medicine in cancer therapy is becoming increasingly important. There already exist drugs administered specifically for patients with tumours presenting well-defined mutations. However, the field is still in its…

生物大分子 · 定量生物学 2024-08-26 Abbi Abdel-Rehim , Oghenejokpeme Orhobor , Gareth Griffiths , Larisa Soldatova , Ross D. King

The personalization of treatment via bio-markers and other risk categories has drawn increasing interest among clinical scientists. Personalized treatment strategies can be learned using data from clinical trials, but such trials are very…

机器学习 · 计算机科学 2012-02-20 Kun Deng , Joelle Pineau , Susan A. Murphy

Predicting which action (treatment) will lead to a better outcome is a central task in decision support systems. To build a prediction model in real situations, learning from biased observational data is a critical issue due to the lack of…

机器学习 · 统计学 2020-06-11 Akira Tanimoto , Tomoya Sakai , Takashi Takenouchi , Hisashi Kashima

We present a deep learning-based approach to studying dynamic clinical behavioral regimes in diverse non-randomized healthcare settings. Our proposed methodology - deep causal behavioral policy learning (DC-BPL) - uses deep learning…

机器学习 · 统计学 2025-03-06 Jonas Knecht , Anna Zink , Jonathan Kolstad , Maya Petersen

Learned visuomotor policies have shown considerable success as an alternative to traditional, hand-crafted frameworks for robotic manipulation. Surprisingly, an extension of these methods to the multiview domain is relatively unexplored. A…

机器人学 · 计算机科学 2022-07-11 Trevor Ablett , Yifan Zhai , Jonathan Kelly

Health policy decisions regarding patient treatment strategies require consideration of both treatment effectiveness and cost. Optimizing treatment rules with respect to effectiveness may result in prohibitively expensive strategies; on the…

统计方法学 · 统计学 2021-10-20 Nicholas Illenberger , Andrew J. Spieker , Nandita Mitra

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

A treatment regime formalizes personalized medicine as a function from individual patient characteristics to a recommended treatment. A high-quality treatment regime can improve patient outcomes while reducing cost, resource consumption,…

统计方法学 · 统计学 2015-04-30 Yichi Zhang , Eric B. Laber , Anastasios Tsiatis , Marie Davidian

In many medical and business applications, researchers are interested in estimating individualized treatment effects using data from a randomized experiment. For example in medical applications, doctors learn the treatment effects from…

统计方法学 · 统计学 2022-03-01 Kevin Wu Han , Han Wu

Machine learning (ML) estimates of conditional average treatment effects (CATE) can guide policy decisions, either by allowing targeting of individuals with beneficial CATE estimates, or as inputs to decision trees that optimise overall…

计量经济学 · 经济学 2023-10-04 Julia Hatamyar , Noemi Kreif