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In many settings, a decision-maker wishes to learn a rule, or policy, that maps from observable characteristics of an individual to an action. Examples include selecting offers, prices, advertisements, or emails to send to consumers, as…

机器学习 · 统计学 2018-11-20 Zhengyuan Zhou , Susan Athey , Stefan Wager

We present a new approach to the problems of evaluating and learning personalized decision policies from observational data of past contexts, decisions, and outcomes. Only the outcome of the enacted decision is available and the historical…

机器学习 · 统计学 2019-06-04 Nathan Kallus

Decision-making in personalized medicine such as cancer therapy or critical care must often make choices for dosage combinations, i.e., multiple continuous treatments. Existing work for this task has modeled the effect of multiple…

机器学习 · 计算机科学 2023-10-30 Jonas Schweisthal , Dennis Frauen , Valentyn Melnychuk , Stefan Feuerriegel

Laboratory testing is an integral tool in the management of patient care in hospitals, particularly in intensive care units (ICUs). There exists an inherent trade-off in the selection and timing of lab tests between considerations of the…

人工智能 · 计算机科学 2019-11-01 Li-Fang Cheng , Niranjani Prasad , Barbara E Engelhardt

In treatment allocation problems the individuals to be treated often arrive sequentially. We study a problem in which the policy maker is not only interested in the expected cumulative welfare but is also concerned about the…

机器学习 · 统计学 2018-08-24 Anders Bredahl Kock , Martin Thyrsgaard

Precision medicine has the potential to tailor treatment decisions to individual patients using machine learning (ML) and artificial intelligence (AI), but it faces significant challenges due to complex biases in clinical observational data…

Reinforcement learning (RL) has the potential to significantly improve clinical decision making. However, treatment policies learned via RL from observational data are sensitive to subtle choices in study design. We highlight a simple…

机器学习 · 计算机科学 2020-12-23 Christina X. Ji , Michael Oberst , Sanjat Kanjilal , David Sontag

We study the problem of a decision maker who must provide the best possible treatment recommendation based on an experiment. The desirability of the outcome distribution resulting from the policy recommendation is measured through a…

计量经济学 · 经济学 2022-04-06 Anders Bredahl Kock , David Preinerstorfer , Bezirgen Veliyev

We propose an approach for learning optimal tree-based prescription policies directly from data, combining methods for counterfactual estimation from the causal inference literature with recent advances in training globally-optimal decision…

机器学习 · 计算机科学 2020-12-07 Maxime Amram , Jack Dunn , Ying Daisy Zhuo

Recent statistical and reinforcement learning methods have significantly advanced patient care strategies. However, these approaches face substantial challenges in high-stakes contexts, including missing data, inherent stochasticity, and…

Identifying who should be treated is a central question in economics. There are two competing approaches to targeting - paternalistic and autonomous. In the paternalistic approach, policymakers optimally target the policy given observable…

We address the problem of learning a decision policy from observational data of past decisions in contexts with features and associated outcomes. The past policy maybe unknown and in safety-critical applications, such as medical decision…

机器学习 · 计算机科学 2020-06-04 Muhammad Osama , Dave Zachariah , Peter Stoica

Decision-makers frequently must choose a single action from a finite set of alternatives -- for example, physicians selecting a treatment, investors choosing a portfolio risk level, or judges determining sentences. To improve outcomes,…

应用统计 · 统计学 2026-05-19 Raphaël Langevin

This chapter covers different approaches to policy evaluation for assessing the causal effect of a treatment or intervention on an outcome of interest. As an introduction to causal inference, the discussion starts with the experimental…

计量经济学 · 经济学 2019-10-03 Martin Huber

Unlike classical causal inference, which often has an average causal effect of a treatment within a population as a target, in settings such as personalized medicine, the goal is to map a given unit's characteristics to a treatment tailored…

统计方法学 · 统计学 2017-09-13 Ilya Shpitser , Sourjya Sarkar

We consider a general difference-in-differences model in which the treatment variable of interest may be non-binary and its value may change in each period. It is generally difficult to estimate treatment parameters defined with the…

计量经济学 · 经济学 2023-05-30 Takahide Yanagi

To promote precision medicine, individualized treatment regimes (ITRs) are crucial for optimizing the expected clinical outcome based on patient-specific characteristics. However, existing ITR research has primarily focused on scenarios…

统计方法学 · 统计学 2024-02-20 Chang Wang , Lu Wang

Consider a setting in which a policy maker assigns subjects to treatments, observing each outcome before the next subject arrives. Initially, it is unknown which treatment is best, but the sequential nature of the problem permits learning…

计量经济学 · 经济学 2020-08-13 Anders Bredahl Kock , David Preinerstorfer , Bezirgen Veliyev

Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time.…

机器学习 · 统计学 2017-11-07 Hossein Soleimani , Adarsh Subbaswamy , Suchi Saria

Personalized treatment decisions have become an integral part of modern medicine. Thereby, the aim is to make treatment decisions based on individual patient characteristics. Numerous methods have been developed for learning such policies…

机器学习 · 统计学 2023-06-27 Daniel Tschernutter , Tobias Hatt , Stefan Feuerriegel