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Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

计算机视觉与模式识别 · 计算机科学 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Lung nodule classification is a class imbalanced problem, as nodules are found with much lower frequency than non-nodules. In the class imbalanced problem, conventional classifiers tend to be overwhelmed by the majority class and ignore the…

计算机视觉与模式识别 · 计算机科学 2017-12-19 Masaharu Sakamoto , Hiroki Nakano , Kun Zhao , Taro Sekiyama

The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Pulmonary nodule detection plays an important role in lung cancer screening with low-dose computed tomography (CT) scans. It remains challenging to build nodule detection deep learning models with good generalization performance due to…

计算机视觉与模式识别 · 计算机科学 2020-02-10 Yuemeng Li , Yong Fan

Hispathological image segmentation algorithms play a critical role in computer aided diagnosis technology. The development of weakly supervised segmentation algorithm alleviates the problem of medical image annotation that it is…

计算机视觉与模式识别 · 计算机科学 2022-05-19 Ziniu Qian , Kailu Li , Maode Lai , Eric I-Chao Chang , Bingzheng Wei , Yubo Fan , Yan Xu

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

图像与视频处理 · 电气工程与系统科学 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang

Multiple instance learning (MIL) significantly reduced annotation costs via bag-level weak labels for large-scale images, such as histopathological whole slide images (WSIs). However, its adaptability to continual tasks with minimal…

计算机视觉与模式识别 · 计算机科学 2025-07-09 Byung Hyun Lee , Wongi Jeong , Woojae Han , Kyoungbun Lee , Se Young Chun

The integration of Internet of Things (IoT) technology in pulmonary nodule detection significantly enhances the intelligence and real-time capabilities of the detection system. Currently, lung nodule detection primarily focuses on the…

图像与视频处理 · 电气工程与系统科学 2025-03-14 Meng Wang , Zi Yang , Ruifeng Zhao , Yaoting Jiang

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

人工智能 · 计算机科学 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

Multiple instance learning (MIL) is a variation of supervised learning where a single class label is assigned to a bag of instances. In this paper, we state the MIL problem as learning the Bernoulli distribution of the bag label where the…

机器学习 · 计算机科学 2018-06-29 Maximilian Ilse , Jakub M. Tomczak , Max Welling

Lung cancer continues to be the leading cause of cancer-related deaths globally. Early detection and diagnosis of pulmonary nodules are essential for improving patient survival rates. Although previous research has integrated multimodal and…

计算机视觉与模式识别 · 计算机科学 2025-12-25 Xiao Yu , Zhaojie Fang , Guanyu Zhou , Yin Shen , Huoling Luo , Ye Li , Ahmed Elazab , Xiang Wan , Ruiquan Ge , Changmiao Wang

Multiple Instance Learning (MIL) has been widely applied to medical imaging diagnosis, where bag labels are known and instance labels inside bags are unknown. Traditional MIL assumes that instances in each bag are independent samples from a…

图像与视频处理 · 电气工程与系统科学 2023-07-19 Yunan Wu , Francisco M. Castro-Macías , Pablo Morales-Álvarez , Rafael Molina , Aggelos K. Katsaggelos

The progression of lung cancer implies the intrinsic ordinal relationship of lung nodules at different stages-from benign to unsure then to malignant. This problem can be solved by ordinal regression methods, which is between classification…

计算机视觉与模式识别 · 计算机科学 2021-02-02 Yiming Lei , Hongming Shan , Junping Zhang

An accurate segmentation of lung nodules in computed tomography (CT) images is critical to lung cancer analysis and diagnosis. However, due to the variety of lung nodules and the similarity of visual characteristics between nodules and…

计算机视觉与模式识别 · 计算机科学 2019-05-22 Haichao Cao , Hong Liu , Enmin Song , Chih-Cheng Hung , Guangzhi Ma , Xiangyang Xu , Renchao Jin , Jianguo Lu

The mortality of lung cancer has ranked high among cancers for many years. Early detection of lung cancer is critical for disease prevention, cure, and mortality rate reduction. However, existing detection methods on pulmonary nodules…

图像与视频处理 · 电气工程与系统科学 2022-05-13 Juanyun Mai , Minghao Wang , Jiayin Zheng , Yanbo Shao , Zhaoqi Diao , Xinliang Fu , Yulong Chen , Jianyu Xiao , Jian You , Airu Yin , Yang Yang , Xiangcheng Qiu , Jinsheng Tao , Bo Wang , Hua Ji

Due to the complexity of annotation and inter-annotator variability, most lung nodule malignancy grading datasets contain label noise, which inevitably degrades the performance and generalizability of models. Although researchers adopt the…

计算机视觉与模式识别 · 计算机科学 2023-08-21 Xianze Ai , Zehui Liao , Yong Xia

Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations. Often, this approach directly applies "natural image…

Lung cancer follow-up is a complex, error prone, and time consuming task for clinical radiologists. Several lung CT scan images taken at different time points of a given patient need to be individually inspected, looking for possible…

图像与视频处理 · 电气工程与系统科学 2019-12-24 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel Ángel González Ballester

Background: Image classification can be considered one of the key pillars of medical image analysis. Deep learning (DL) faces challenges that prevent its practical applications despite the remarkable improvement in medical image…

图像与视频处理 · 电气工程与系统科学 2026-02-19 Shahabedin Nabavi , Kian Anvari Hamedani , Mohsen Ebrahimi Moghaddam , Ahmad Ali Abin , Alejandro F. Frangi

In this work, we present a fully automated lung computed tomography (CT) cancer diagnosis system, DeepLung. DeepLung consists of two components, nodule detection (identifying the locations of candidate nodules) and classification…

计算机视觉与模式识别 · 计算机科学 2018-01-30 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie