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In this paper, we propose a novel framework with 3D convolutional networks (ConvNets) for automated detection of pulmonary nodules from low-dose CT scans, which is a challenging yet crucial task for lung cancer early diagnosis and…

计算机视觉与模式识别 · 计算机科学 2017-08-15 Qi Dou , Hao Chen , Yueming Jin , Huangjing Lin , Jing Qin , Pheng-Ann Heng

Though multiple instance learning (MIL) has been a foundational strategy in computational pathology for processing whole slide images (WSIs), current approaches are designed for traditional hematoxylin and eosin (H&E) slides rather than…

图像与视频处理 · 电气工程与系统科学 2024-11-15 Marc Harary , Eliezer M. Van Allen , William Lotter

Lung nodule malignancy prediction is an essential step in the early diagnosis of lung cancer. Besides the difficulties commonly discussed, the challenges of this task also come from the ambiguous labels provided by annotators, since deep…

图像与视频处理 · 电气工程与系统科学 2021-04-26 Zehui Liao , Yutong Xie , Shishuai Hu , Yong Xia

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

定量方法 · 定量生物学 2016-11-29 He Yang , Hengyong Yu , Ge Wang

Despite being resource-intensive to train, 3D convolutional neural networks (CNNs) have been the standard approach to classify CT and MRI scans. Recent work suggests that deep multiple instance learning (MIL) may be a more efficient…

机器学习 · 计算机科学 2026-04-30 Ethan Harvey , Dennis Johan Loevlie , Amir Ali Satani , Wansu Chen , David M. Kent , Michael C. Hughes

Early detection of lung nodules with computed tomography (CT) is critical for the longer survival of lung cancer patients and better quality of life. Computer-aided detection/diagnosis (CAD) is proven valuable as a second or concurrent…

计算机视觉与模式识别 · 计算机科学 2022-10-19 Chuang Niu , Ge Wang

Lung nodule malignancy prediction has been enhanced by advanced deep-learning techniques and effective tricks. Nevertheless, current methods are mainly trained with cross-entropy loss using one-hot categorical labels, which results in…

计算机视觉与模式识别 · 计算机科学 2023-10-03 Yiming Lei , Zilong Li , Yan Shen , Junping Zhang , Hongming Shan

Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious,…

计算机视觉与模式识别 · 计算机科学 2020-07-24 Ario Sadafi , Asya Makhro , Anna Bogdanova , Nassir Navab , Tingying Peng , Shadi Albarqouni , Carsten Marr

Pulmonary pathologies are a significant global health concern, often leading to fatal outcomes if not diagnosed and treated promptly. Chest radiography serves as a primary diagnostic tool, but the availability of experienced radiologists…

图像与视频处理 · 电气工程与系统科学 2024-12-17 Abdelbaki Souid , Mohamed Hamroun , Soufiene Ben Othman , Hedi Sakli , Naceur Abdelkarim

A new multi-attention based method for solving the MIL problem (MAMIL), which takes into account the neighboring patches or instances of each analyzed patch in a bag, is proposed. In the method, one of the attention modules takes into…

机器学习 · 计算机科学 2021-12-14 Andrei V. Konstantinov , Lev V. Utkin

Convolutional Neural Networks (CNNs) require a large amount of annotated data to learn from, which is often difficult to obtain in the medical domain. In this paper we show that the sample complexity of CNNs can be significantly improved by…

机器学习 · 计算机科学 2019-04-23 Marysia Winkels , Taco S. Cohen

Deep learning-based classification of rare anemia disorders is challenged by the lack of training data and instance-level annotations. Multiple Instance Learning (MIL) has shown to be an effective solution, yet it suffers from low accuracy…

机器学习 · 计算机科学 2022-07-06 Salome Kazeminia , Ario Sadafi , Asya Makhro , Anna Bogdanova , Shadi Albarqouni , Carsten Marr

Accurate detection of pulmonary nodules with high sensitivity and specificity is essential for automatic lung cancer diagnosis from CT scans. Although many deep learning-based algorithms make great progress for improving the accuracy of…

图像与视频处理 · 电气工程与系统科学 2019-07-30 Jingya Liu , Liangliang Cao , Oguz Akin , Yingli Tian

Motivated by the increasing popularity of attention mechanisms, we observe that popular convolutional (conv.) attention models like Squeeze-and-Excite (SE) and Convolutional Block Attention Module (CBAM) rely on expensive multi-layer…

计算机视觉与模式识别 · 计算机科学 2024-07-22 Majedaldein Almahasneh , Xianghua Xie , Adeline Paiement

Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans.…

计算机视觉与模式识别 · 计算机科学 2018-06-19 Raunak Dey , Zhongjie Lu , Yi Hong

Multi-modal learning has shown exceptional performance in various tasks, especially in medical applications, where it integrates diverse medical information for comprehensive diagnostic evidence. However, there still are several challenges…

机器学习 · 计算机科学 2024-11-19 Lin Fan , Yafei Ou , Cenyang Zheng , Pengyu Dai , Tamotsu Kamishima , Masayuki Ikebe , Kenji Suzuki , Xun Gong

Identifying unique polyps in colon capsule endoscopy (CCE) images is a critical yet challenging task for medical personnel due to the large volume of images, the cognitive load it creates for clinicians, and the ambiguity in labeling…

计算机视觉与模式识别 · 计算机科学 2026-01-22 Puneet Sharma , Kristian Dalsbø Hindberg , Eibe Frank , Benedicte Schelde-Olesen , Ulrik Deding

Though large-scale datasets are essential for training deep learning systems, it is expensive to scale up the collection of medical imaging datasets. Synthesizing the objects of interests, such as lung nodules, in medical images based on…

Lung nodules suffer large variation in size and appearance in CT images. Nodules less than 10mm can easily lose information after down-sampling in convolutional neural networks, which results in low sensitivity. In this paper, a combination…

计算机视觉与模式识别 · 计算机科学 2018-08-02 Benyuan Sun , Zhen Zhou , Fandong Zhang , Xiuli Li , Yizhou Wang