相关论文: Relaxing constraints on data acquisition and posit…
Optical tweezers (OT) have become an essential technique in several fields of physics, chemistry, and biology as precise micromanipulation tools and microscopic force transducers. Quantitative measurements require the accurate calibration…
Optical tweezers are highly versatile laser traps for neutral microparticles, with fundamental applications in physics and in single molecule cell biology. Force measurements are performed by converting the stiffness response to…
We explain and demonstrate a new method of force- and position-calibration for optical tweezers with back-focal-plane photo detection. The method combines power spectral measurements of thermal motion and the response to a sinusoidal motion…
Optically levitated dielectric nanoparticles have become valuable tools for precision sensing and quantum optomechanical experiments. To predict the dynamic properties of a particle trapped in an optical tweezer with high fidelity, a tool…
Dual trap optical tweezers are often used in high-resolution measurements in single-molecule biophysics. Such measurements can be hindered by the presence of extraneous noise sources, the most prominent of which is the coupling of…
Optical tweezers equipped with position detection allow for application of piconewton-scale forces and high-temporal-resolution measurements of nanometer-scale motion. While typically used for trapping microscopic objects, the optical…
We present a dual-trap optical tweezers setup which directly measures forces using linear momentum conservation. The setup uses a counter-propagating geometry, which allows momentum measurement on each beam separately. The experimental…
Optical tweezers are a powerful tool for the precise positioning of a variety of small objects, including single neutral atoms. Once trapped, atoms can be cooled to the motional ground state of the tweezers. For a more advanced control of…
We demonstrate a lock-in particle tracking scheme in optical tweezers based on stroboscopic modulation of an illuminating optical field. This scheme is found to evade low frequency noise sources while otherwise producing an equivalent…
In recent years, levitated particles of optical traps in vacuum have shown enormous potential in precision sensor development and searching for new physics. The accuracy of the calibration relating the detected signal to absolute…
Rotational optical tweezers are used to probe the mechanical properties of unknown microsystems. Quantifying the angular trap stiffness is essential for interpreting the rotational dynamics of probe particles. While methods to determine…
Plasmonic nano-optical tweezers enable the non-invasive manipulation of nano-objects under low illumination intensities, and have become a powerful tool for nanotechnology and biophysics. However, measuring the trap stiffness of…
Optical tweezers enable non-contact trapping of micro-scale objects using light. Despite their widespread use, it is currently not known how tightly it is possible to three-dimensionally trap micro-particles with a given photon budget.…
Calibration of optically trapped particles in-vivo has been complicated given the frequency dependence and spatial inhomogeneity of the cytoplasmic viscosity, and the requirement of accurate knowledge of the medium refractive index.…
Here we present a computational tool for optical tweezers which calculates the particle tracking signal measured with a quadrant detector and the shot-noise limit to position resolution. The tool is a piece of Matlab code which functions…
The dynamics of an optically trapped particle are often determined by measuring intensity shifts of the back-scattered light from the particle using position sensitive detectors. We present a technique which measures the phase of the…
We have recently demonstrated the creation of regular strings of neutral caesium atoms in a standing wave optical dipole trap using optical tweezers [Y. Miroshnychenko et al., Nature, in press (2006)]. The rearrangement is realized…
Recently, acoustic tweezers based on an array of ultrasonic transducers have been reported taking inspiration from holographic optical tweezers. In the latter technique, the calibration of the optical trap is an essential procedure to…
Optical tweezers has emerged as a powerful tool in manipulating microscopic particles and in measuring weak forces of the order of a pico-Newton. As a result, it has found wide applications ranging from material science to biology.…
Since their invention in the 1980s [1], optical tweezers have found a wide range of applications, from biophotonics and mechanobiology to microscopy and optomechanics [2, 3, 4, 5]. Simulations of the motion of microscopic particles held by…