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Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Deep learning (DL) models have achieved strong performance in an intelligence healthcare setting, yet most existing approaches operate as black boxes and ignore the physical processes that govern tumor growth, limiting interpretability,…

机器学习 · 计算机科学 2026-03-31 Pulock Das , Al Amin , Kamrul Hasan , Rohan Thompson , Azubike D. Okpalaeze , Liang Hong

Precise and scalable instance segmentation of cell nuclei is essential for computational pathology, yet gigapixel Whole-Slide Images pose major computational challenges. Existing approaches rely on patch-based processing and costly…

计算机视觉与模式识别 · 计算机科学 2026-01-07 Matěj Pekár , Vít Musil , Rudolf Nenutil , Petr Holub , Tomáš Brázdil

The segmentation of kidney layer structures, including cortex, outer stripe, inner stripe, and inner medulla within human kidney whole slide images (WSI) plays an essential role in automated image analysis in renal pathology. However, the…

图像与视频处理 · 电气工程与系统科学 2023-09-07 Muhao Liu , Chenyang Qi , Shunxing Bao , Quan Liu , Ruining Deng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

We propose a new method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI). The cancer subtype should be classified by referring to a…

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

图像与视频处理 · 电气工程与系统科学 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Pathological diagnosis is the gold standard for tumor diagnosis, and nucleus instance segmentation is a key step in digital pathology analysis and pathological diagnosis. However, the computational efficiency of the model and the treatment…

图像与视频处理 · 电气工程与系统科学 2025-05-09 Shengchun Xiong , Xiangru Li , Yunpeng Zhong , Wanfen Peng

Computational Pathology CPath is an interdisciplinary science that augments developments of computational approaches to analyze and model medical histopathology images. The main objective for CPath is to develop infrastructure and workflows…

Whole slide imaging (WSI) refers to the digitization of a tissue specimen which enables pathologists to explore high-resolution images on a monitor rather than through a microscope. The formation of tissue folds occur during tissue…

图像与视频处理 · 电气工程与系统科学 2019-03-19 Morteza Babaie , H. R. Tizhoosh

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

Melanoma is an aggressive form of skin cancer with rapid progression and high metastatic potential. Accurate characterisation of tissue morphology in melanoma is crucial for prognosis and treatment planning. However, manual segmentation of…

图像与视频处理 · 电气工程与系统科学 2025-07-21 Jiaqi Lv , Yijie Zhu , Carmen Guadalupe Colin Tenorio , Brinder Singh Chohan , Mark Eastwood , Shan E Ahmed Raza

Skin cancer is a common and fast rising malignancy worldwide. Early detection is critical for improving outcomes. Deep learning models trained on dermoscopic and clinical images can support automated and fast triage. However, many studies…

计算机视觉与模式识别 · 计算机科学 2026-05-27 Durjoy Dey , Yuhong Yan , Hassan Hajjdiab

Automated cervical nucleus segmentation based on deep learning can effectively improve the quantitative analysis of cervical cancer. However, accurate nuclei segmentation is still challenging. The classic U-net has not achieved satisfactory…

图像与视频处理 · 电气工程与系统科学 2019-11-13 Jie Zhao , Lei Dai , Mo Zhang , Fei Yu , Meng Li , Hongfeng Li , Wenjia Wang , Li Zhang

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

计算机视觉与模式识别 · 计算机科学 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

Cancer is a highly heterogeneous disease with significant variability in molecular features and clinical outcomes, making diagnosis and treatment challenging. In recent years, high-throughput omic technologies have facilitated the discovery…

定量方法 · 定量生物学 2024-08-19 Saiful Islam , Md. Nahid Hasan

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

计算机视觉与模式识别 · 计算机科学 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Knowledge of molecular subtypes of gliomas can provide valuable information for tailored therapies. This study aimed to investigate the use of deep convolutional neural networks (DCNNs) for noninvasive glioma subtyping with radiological…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Dong Wei , Yiming Li , Yinyan Wang , Tianyi Qian , Yefeng Zheng

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

定量方法 · 定量生物学 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Pathological image analysis is a crucial field in computer-aided diagnosis, where deep learning is widely applied. Transfer learning using pre-trained models initialized on natural images has effectively improved the downstream pathological…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Nan Ying , Yanli Lei , Tianyi Zhang , Shangqing Lyu , Chunhui Li , Sicheng Chen , Zeyu Liu , Yu Zhao , Guanglei Zhang