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In the context of medical decision making, counterfactual prediction enables clinicians to predict treatment outcomes of interest under alternative courses of therapeutic actions given observed patient history. In this work, we present…

机器学习 · 计算机科学 2024-09-27 Hong Xiong , Feng Wu , Leon Deng , Megan Su , Li-wei H Lehman

Decision-makers are faced with the challenge of estimating what is likely to happen when they take an action. For instance, if I choose not to treat this patient, are they likely to die? Practitioners commonly use supervised learning…

机器学习 · 统计学 2018-02-02 Peter Schulam , Suchi Saria

Counterfactual prediction is about predicting outcome of the unobserved situation from the data. For example, given patient is on drug A, what would be the outcome if she switch to drug B. Most of existing works focus on modeling…

机器学习 · 计算机科学 2020-10-29 Yanbo Xu , Cao Xiao , Jimeng Sun

Estimating potential outcomes for treatments over time based on observational data is important for personalized decision-making in medicine. However, many existing methods for this task fail to properly adjust for time-varying confounding…

机器学习 · 计算机科学 2026-02-18 Konstantin Hess , Dennis Frauen , Valentyn Melnychuk , Stefan Feuerriegel

Counterfactual learning has become promising for understanding and modeling causality in complex and dynamic systems. This paper presents a novel method for counterfactual learning in the context of multivariate time series analysis and…

机器学习 · 计算机科学 2026-03-03 Gianlucca Zuin , Adriano Veloso

In a clinical trial, the random allocation aims to balance prognostic factors between arms, preventing true confounders. However, residual differences due to chance may introduce near-confounders. Adjusting on prognostic factors is…

统计方法学 · 统计学 2024-11-18 Joe de Keizer , Rémi Lenain , Raphaël Porcher , Sarah Zoha , Arthur Chatton , Yohann Foucher

The g-formula can be used to estimate causal effects of sustained treatment strategies using observational data under the identifying assumptions of consistency, positivity, and exchangeability. The non-iterative conditional expectation…

机器学习 · 统计学 2024-10-30 Sophia M Rein , Jing Li , Miguel Hernan , Andrew Beam

Estimating counterfactual outcomes over time from observational data is relevant for many applications (e.g., personalized medicine). Yet, state-of-the-art methods build upon simple long short-term memory (LSTM) networks, thus rendering…

机器学习 · 计算机科学 2022-06-06 Valentyn Melnychuk , Dennis Frauen , Stefan Feuerriegel

Data-driven decision making frequently relies on predicting counterfactual outcomes. In practice, researchers commonly train counterfactual prediction models on a source dataset to inform decisions on a possibly separate target population.…

机器学习 · 统计学 2026-04-07 Keith Barnatchez , Kevin P. Josey , Rachel C. Nethery , Giovanni Parmigiani

Identifying when to give treatments to patients and how to select among multiple treatments over time are important medical problems with a few existing solutions. In this paper, we introduce the Counterfactual Recurrent Network (CRN), a…

机器学习 · 计算机科学 2020-02-12 Ioana Bica , Ahmed M. Alaa , James Jordon , Mihaela van der Schaar

Counterfactual explanation is a common class of methods to make local explanations of machine learning decisions. For a given instance, these methods aim to find the smallest modification of feature values that changes the predicted…

人工智能 · 计算机科学 2022-12-22 Victor Guyomard , Françoise Fessant , Thomas Guyet , Tassadit Bouadi , Alexandre Termier

Estimating what would be an individual's potential response to varying levels of exposure to a treatment is of high practical relevance for several important fields, such as healthcare, economics and public policy. However, existing methods…

机器学习 · 计算机科学 2020-12-11 Patrick Schwab , Lorenz Linhardt , Stefan Bauer , Joachim M. Buhmann , Walter Karlen

Graph-structured data are pervasive in the real-world such as social networks, molecular graphs and transaction networks. Graph neural networks (GNNs) have achieved great success in representation learning on graphs, facilitating various…

机器学习 · 计算机科学 2025-02-27 Zhimeng Guo , Teng Xiao , Zongyu Wu , Charu Aggarwal , Hui Liu , Suhang Wang

Machine learning is increasingly applied in high-stakes decision making that directly affect people's lives, and this leads to an increased demand for systems to explain their decisions. Explanations often take the form of counterfactuals,…

机器学习 · 计算机科学 2021-05-20 Maximilian Schleich , Zixuan Geng , Yihong Zhang , Dan Suciu

Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time.…

机器学习 · 统计学 2017-11-07 Hossein Soleimani , Adarsh Subbaswamy , Suchi Saria

Estimating the counterfactual outcome of treatment is essential for decision-making in public health and clinical science, among others. Often, treatments are administered in a sequential, time-varying manner, leading to an exponentially…

机器学习 · 统计学 2024-07-16 Shenghao Wu , Wenbin Zhou , Minshuo Chen , Shixiang Zhu

This paper introduces a simple framework of counterfactual estimation for causal inference with time-series cross-sectional data, in which we estimate the average treatment effect on the treated by directly imputing counterfactual outcomes…

统计方法学 · 统计学 2022-08-16 Licheng Liu , Ye Wang , Yiqing Xu

Estimating causal effects from spatiotemporal observational data is essential in public health, environmental science, and policy evaluation, where randomized experiments are often infeasible. Existing approaches, however, either rely on…

机器学习 · 计算机科学 2025-10-29 Miruna Oprescu , David K. Park , Xihaier Luo , Shinjae Yoo , Nathan Kallus

G-computation is a useful estimation method that can be adapted to address various biases in epidemiology. However, these adaptations may not be obvious for some complex causal structures. This challenge is an example of the much wider…

统计方法学 · 统计学 2025-08-01 Paul N Zivich , Haidong Lu

We propose an interactive methodology for generating counterfactual explanations for univariate time series data in classification tasks by leveraging 2D projections and decision boundary maps to tackle interpretability challenges. Our…

机器学习 · 计算机科学 2024-08-21 Udo Schlegel , Julius Rauscher , Daniel A. Keim
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